Embryonic Stem Cell (ES)-Specific Enhancers Specify the Expression Potential of ES Genes in Cancer

por Aran, Dvir, Abu-Remaileh, Monther, Levy, Revital, Meron, Nurit, Toperoff, Gidon, Edrei, Yifat, Bergman, Yehudit, Hellman, Asaf
Publicado 2016

Ferroptosis regulation by the NGLY1/NFE2L1 pathway

por Forcina, Giovanni C., Pope, Lauren, Murray, Magdalena, Dong, Wentao, Abu-Remaileh, Monther, Bertozzi, Carolyn R., Dixon, Scott J.
Publicado 2022

WWOX somatic ablation in skeletal muscles alters glucose metabolism

por Abu-Remaileh, Muhannad, Abu-Remaileh, Monther, Akkawi, Rania, Knani, Ibrahim, Udi, Shiran, Pacold, Micheal E., Tam, Joseph, Aqeilan, Rami I.
Publicado 2019

Lysosomal cathepsin D mediates endogenous mucin glycodomain catabolism in mammals

por Pedram, Kayvon, Laqtom, Nouf N., Shon, D. Judy, Di Spiezio, Alessandro, Riley, Nicholas M., Saftig, Paul, Abu-Remaileh, Monther, Bertozzi, Carolyn R.
Publicado 2022

De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes

por Epsztejn-Litman, Silvina, Feldman, Nirit, Abu-Remaileh, Monther, Shufaro, Yoel, Gerson, Ariela, Ueda, Jun, Deplus, Rachel, Fuks, François, Shinkai, Yoichi, Cedar, Howard, Bergman, Yehudit
Publicado 2008

An SPNS1-dependent lysosomal lipid transport pathway that enables cell survival under choline limitation

por Scharenberg, Samantha G., Dong, Wentao, Ghoochani, Ali, Nyame, Kwamina, Levin-Konigsberg, Roni, Krishnan, Aswini R., Rawat, Eshaan S., Spees, Kaitlyn, Bassik, Michael C., Abu-Remaileh, Monther
Publicado 2023

Golgi-IP, a tool for multimodal analysis of Golgi molecular content

por Fasimoye, Rotimi, Dong, Wentao, Nirujogi, Raja S., Rawat, Eshaan S., Iguchi, Miharu, Nyame, Kwamina, Phung, Toan K., Bagnoli, Enrico, Prescott, Alan R., Alessi, Dario R., Abu-Remaileh, Monther
Publicado 2023

Aberrant DNA Methylation in ES Cells

por Ludwig, Guy, Nejman, Deborah, Hecht, Merav, Orlanski, Shari, Abu-Remaileh, Monther, Yanuka, Ofra, Sandler, Oded, Marx, Amichai, Roberts, Douglas, Benvenisty, Nissim, Bergman, Yehudit, Mendelsohn, Monica, Cedar, Howard
Publicado 2014

Histidine catabolism is a major determinant of methotrexate sensitivity

por Kanarek, Naama, Keys, Heather R., Cantor, Jason R., Lewis, Caroline A., Chan, Sze Ham, Kunchok, Tenzin, Abu-Remaileh, Monther, Freinkman, Elizaveta, Schweitzer, Lawrence D., Sabatini, David M.
Publicado 2018

Carnitine octanoyltransferase is important for the assimilation of exogenous acetyl-L-carnitine into acetyl-CoA in mammalian cells

por Hsu, Jake, Fatuzzo, Nina, Weng, Nielson, Michno, Wojciech, Dong, Wentao, Kienle, Maryline, Dai, Yuqin, Pasca, Anca, Abu-Remaileh, Monther, Rasgon, Natalie, Bigio, Benedetta, Nasca, Carla, Khosla, Chaitan
Publicado 2022

Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing bisphosphonates

por Yu, Zhou, Surface, Lauren E, Park, Chong Yon, Horlbeck, Max A, Wyant, Gregory A, Abu-Remaileh, Monther, Peterson, Timothy R, Sabatini, David M, Weissman, Jonathan S, O'Shea, Erin K
Publicado 2018

CNS Repopulation by Hematopoietic-Derived Microglia-Like Cells Corrects Progranulin deficiency

por Colella, Pasqualina, Sayana, Ruhi, Suarez-Nieto, Maria Valentina, Sarno, Jolanda, Nyame, Kwamina, Xiong, Jian, Vera, Luisa Natalia Pimentel, Basurto, Jessica Arozqueta, Corbo, Marco, Limaye, Anay, Davis, Kara Lynn, Abu-Remaileh, Monther, Gomez-Ospina, Natalia
Publicado 2023

KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1

por Wolfson, Rachel L., Chantranupong, Lynne, Wyant, Gregory A., Gu, Xin, Orozco, Jose M., Shen, Kuang, Condon, Kendall J., Petri, Sabrina, Kedir, Jibril, Scaria, Sonia M., Abu-Remaileh, Monther, Frankel, Wayne N., Sabatini, David M.
Publicado 2017

Small molecule C381 targets the lysosome to reduce inflammation and ameliorate disease in models of neurodegeneration

por Vest, Ryan T., Chou, Ching-Chieh, Zhang, Hui, Haney, Michael S., Li, Lulin, Laqtom, Nouf N., Chang, Betty, Shuken, Steven, Nguyen, Andy, Yerra, Lakshmi, Yang, Andrew C., Green, Carol, Tanga, Mary, Abu-Remaileh, Monther, Bassik, Michael C., Frydman, Judith, Luo, Jian, Wyss-Coray, Tony
Publicado 2022

CYP4F2 is a human-specific determinant of circulating N-acyl amino acid levels

por Tanzo, Julia T., Li, Veronica L., Wiggenhorn, Amanda L., Moya-Garzon, Maria Dolores, Wei, Wei, Lyu, Xuchao, Dong, Wentao, Tahir, Usman A., Chen, Zsu-Zsu, Cruz, Daniel E., Deng, Shuliang, Shi, Xu, Zheng, Shuning, Guo, Yan, Sims, Mario, Abu-Remaileh, Monther, Wilson, James G., Gerszten, Robert E., Long, Jonathan Z., Benson, Mark D.
Publicado 2023

Increased lysosomal biomass is responsible for the resistance of triple-negative breast cancers to CDK4/6 inhibition

por Fassl, Anne, Brain, Christopher, Abu-Remaileh, Monther, Stukan, Iga, Butter, Deborah, Stepien, Piotr, Feit, Avery S., Bergholz, Johann, Michowski, Wojciech, Otto, Tobias, Sheng, Qing, Loo, Alice, Michael, Walter, Tiedt, Ralph, DeAngelis, Carmine, Schiff, Rachel, Jiang, Baishan, Jovanovic, Bojana, Nowak, Karolina, Ericsson, Maria, Cameron, Michael, Gray, Nathanael, Dillon, Deborah, Zhao, Jean J., Sabatini, David M., Jeselsohn, Rinath, Brown, Myles, Polyak, Kornelia, Sicinski, Piotr
Publicado 2020

APOE4/4 is linked to damaging lipid droplets in Alzheimer’s microglia

por Haney, Michael S., Pálovics, Róbert, Munson, Christy Nicole, Long, Chris, Johansson, Patrik, Yip, Oscar, Dong, Wentao, Rawat, Eshaan, West, Elizabeth, Schlachetzki, Johannes CM, Tsai, Andy, Guldner, Ian Hunter, Lamichhane, Bhawika S., Smith, Amanda, Schaum, Nicholas, Calcuttawala, Kruti, Shin, Andrew, Wang, Yung-Hua, Wang, Chengzhong, Koutsodendris, Nicole, Serrano, Geidy E, Beach, Thomas G, Reiman, Eric M, Glass, Christopher K, Abu-Remaileh, Monther, Enejder, Annika, Huang, Yadong, Wyss-Coray, Tony
Publicado 2023

High fat diet enhances stemness and tumorigenicity of intestinal progenitors

por Beyaz, Semir, Mana, Miyeko D., Roper, Jatin, Kedrin, Dmitriy, Saadatpour, Assieh, Hong, Sue-Jean, Bauer-Rowe, Khristian E., Xifaras, Michael E., Akkad, Adam, Arias, Erika, Pinello, Luca, Katz, Yarden, Shinagare, Shweta, Abu-Remaileh, Monther, Mihaylova, Maria M., Lamming, Dudley W., Dogum, Rizkullah, Guo, Guoji, Bell, George W., Selig, Martin, Nielsen, G. Petur, Gupta, Nitin, Ferrone, Cristina R., Deshpande, Vikram, Yuan, Guo-Cheng, Orkin, Stuart H., Sabatini, David M., Yilmaz, Ömer H.
Publicado 2016

A PHGDH inhibitor reveals coordination of serine synthesis and 1-carbon unit fate

por Pacold, Michael E., Brimacombe, Kyle R., Chan, Sze Ham, Rohde, Jason M., Lewis, Caroline A., Swier, Lotteke J.Y.M., Possemato, Richard, Chen, Walter W., Sullivan, Lucas B., Fiske, Brian P., Cho, Sung Won, Freinkman, Elizaveta, Birsoy, Kıvanç, Abu-Remaileh, Monther, Shaul, Yoav D., Liu, Chieh Min, Zhou, Minerva, Koh, Min Jung, Chung, Haeyoon, Davidson, Shawn M., Luengo, Alba, Wang, Amy Q., Xu, Xin, Yasgar, Adam, Liu, Li, Rai, Ganesha, Westover, Kenneth D., Vander Heiden, Matthew G., Shen, Min, Gray, Nathanael S., Boxer, Matthew B., Sabatini, David M.
Publicado 2016