Concordance of deregulated mechanisms unveiled in underpowered experiments: PTBP1 knockdown case study

por Gardeux, Vincent, Arslan, Ahmet D, Achour, Ikbel, Ho, Tsui-Ting, Beck, William T, Lussier, Yves A
Publicado 2014

Convergent downstream candidate mechanisms of independent intergenic polymorphisms between co-classified diseases implicate epistasis among noncoding elements()

por Han, Jiali, Li, Jianrong, Achour, Ikbel, Pesce, Lorenzo, Foster, Ian, Li, Haiquan, Lussier, Yves A.
Publicado 2018

Dynamic changes of RNA-sequencing expression for precision medicine: N-of-1-pathways Mahalanobis distance within pathways of single subjects predicts breast cancer survival

por Schissler, A. Grant, Gardeux, Vincent, Li, Qike, Achour, Ikbel, Li, Haiquan, Piegorsch, Walter W., Lussier, Yves A.
Publicado 2015

Flexible ordering of antibody class switch and V(D)J joining during B-cell ontogeny

por Kumar, Satyendra, Wuerffel, Robert, Achour, Ikbel, Lajoie, Bryan, Sen, Ranjan, Dekker, Job, Feeney, Ann J., Kenter, Amy L.
Publicado 2013

In Silico cancer cell versus stroma cellularity index computed from species-specific human and mouse transcriptome of xenograft models: towards accurate stroma targeting therapy as...

por Yang, Xinan, Huang, Yong, Lee, Younghee, Gardeux, Vincent, Achour, Ikbel, Regan, Kelly, Rebman, Ellen, Li, Haiquan, Lussier, Yves A
Publicado 2014

N-of-1-pathways MixEnrich: advancing precision medicine via single-subject analysis in discovering dynamic changes of transcriptomes

por Li, Qike, Schissler, A. Grant, Gardeux, Vincent, Achour, Ikbel, Kenost, Colleen, Berghout, Joanne, Li, Haiquan, Zhang, Hao Helen, Lussier, Yves A.
Publicado 2017

Analysis of aggregated cell–cell statistical distances within pathways unveils therapeutic-resistance mechanisms in circulating tumor cells

por Schissler, A. Grant, Li, Qike, Chen, James L., Kenost, Colleen, Achour, Ikbel, Billheimer, D. Dean, Li, Haiquan, Piegorsch, Walter W., Lussier, Yves A.
Publicado 2016

Network models of genome-wide association studies uncover the topological centrality of protein interactions in complex diseases

por Lee, Younghee, Li, Haiquan, Li, Jianrong, Rebman, Ellen, Achour, Ikbel, Regan, Kelly E, Gamazon, Eric R, Chen, James L, Yang, Xinan Holly, Cox, Nancy J, Lussier, Yves A
Publicado 2013

‘N-of-1-pathways’ unveils personal deregulated mechanisms from a single pair of RNA-Seq samples: towards precision medicine

por Gardeux, Vincent, Achour, Ikbel, Li, Jianrong, Maienschein-Cline, Mark, Li, Haiquan, Pesce, Lorenzo, Parinandi, Gurunadh, Bahroos, Neil, Winn, Robert, Foster, Ian, Garcia, Joe G N, Lussier, Yves A
Publicado 2014

The discriminatory cost of ICD-10-CM transition between clinical specialties: metrics, case study, and mitigating tools

por Boyd, Andrew D, Li, Jianrong ‘John’, Burton, Mike D, Jonen, Michael, Gardeux, Vincent, Achour, Ikbel, Luo, Roger Q, Zenku, Ilir, Bahroos, Neil, Brown, Stephen B, Vanden Hoek, Terry, Lussier, Yves A
Publicado 2013

Integrative genomics analyses unveil downstream biological effectors of disease-specific polymorphisms buried in intergenic regions

por Li, Haiquan, Achour, Ikbel, Bastarache, Lisa, Berghout, Joanne, Gardeux, Vincent, Li, Jianrong, Lee, Younghee, Pesce, Lorenzo, Yang, Xinan, Ramos, Kenneth S, Foster, Ian, Denny, Joshua C, Moore, Jason H, Lussier, Yves A
Publicado 2016

A Randomized Phase II Study of MEDI0680 in Combination with Durvalumab versus Nivolumab Monotherapy in Patients with Advanced or Metastatic Clear-cell Renal Cell Carcinoma

por Voss, Martin H., Azad, Arun A., Hansen, Aaron R., Gray, Jhanelle E., Welsh, Sarah J., Song, Xuyang, Kuziora, Michael, Meinecke, Lina, Blando, Jorge, Achour, Ikbel, Wang, Yi, Walcott, Farzana L., Oosting, Sjoukje F.
Publicado 2022

A genome-by-environment interaction classifier for precision medicine: personal transcriptome response to rhinovirus identifies children prone to asthma exacerbations

por Gardeux, Vincent, Berghout, Joanne, Achour, Ikbel, Schissler, A Grant, Li, Qike, Kenost, Colleen, Li, Jianrong, Shang, Yuan, Bosco, Anthony, Saner, Donald, Halonen, Marilyn J, Jackson, Daniel J, Li, Haiquan, Martinez, Fernando D, Lussier, Yves A
Publicado 2017

Anti-PD-1 monoclonal antibody MEDI0680 in a phase I study of patients with advanced solid malignancies

por Naing, Aung, Infante, Jeffrey, Goel, Sanjay, Burris, Howard, Black, Chelsea, Marshall, Shannon, Achour, Ikbel, Barbee, Susannah, May, Rena, Morehouse, Chris, Pollizzi, Kristen, Song, Xuyang, Steele, Keith, Elgeioushi, Nairouz, Walcott, Farzana, Karakunnel, Joyson, LoRusso, Patricia, Weise, Amy, Eder, Joseph, Curti, Brendan, Oberst, Michael
Publicado 2019

Correction to: 33rd Annual Meeting & Pre-Conference Programs of the Society for Immunotherapy of Cancer (SITC 2018)

por Berry, Sneha, Giraldo, Nicolas, Nguyen, Peter, Green, Benjamin, Xu, Haiying, Ogurtsova, Aleksandra, Soni, Abha, Succaria, Farah, Wang, Daphne, Roberts, Charles, Stein, Julie, Engle, Elizabeth, Pardoll, Drew, Anders, Robert, Cottrell, Tricia, Taube, Janis M., Tran, Ben, Voskoboynik, Mark, Kuo, James, Bang, Yung-Lue, Chung, Hyun-Cheo, Ahn, Myung-Ju, Kim, Sang-We, Perera, Ayesh, Freeman, Daniel, Achour, Ikbel, Faggioni, Raffaella, Xiao, Feng, Ferte, Charles, Lemech, Charlotte, Meric-Bernstam, Funda, Werner, Theresa, Hodi, Stephen, Messersmith, Wells, Lewis, Nancy, Talluto, Craig, Dostalek, Mirek, Tao, Aiyang, McWhirter, Sarah, Trujillo, Damian, Luke, Jason, Xu, Chunxiao, BoMarelli, Qi, Jin, Qin, Guozhong, Yu, Huakui, Jenkins, Molly, Lo, Kin-Ming, Halle, Joern-Peter, Lan, Yan, Taylor, Matthew, Vogelzang, Nicholas, Cohn, Allen, Stepan, Daniel, Shumaker, Robert, Dutcus, Corina, Guo, Matthew, Schmidt, Emmett, Rasco, Drew, Brose, Marcia, Vogelzang, Nicholas, Di Simone, Christopher, Jain, Sharad, Richards, Donald, Encarnacion, Carlos, Rasco, Drew, Shumaker, Robert, Dutcus, Corina, Stepan, Daniel, Guo, Matthew, Schmidt, Emmett, Taylor, Matthew, Vogelzang, Nicholas, Encarnacion, Carlos, Cohn, Allen, Di Simone, Christopher, Rasco, Drew, Richards, Donald, Taylor, Matthew, Dutcus, Corina, Stepan, Daniel, Shumaker, Robert, Guo, Matthew, Schmidt, Emmett, Mier, James, An, Jeongshin, Yang, Yeun-yeoul, Lee, Won-Hee, Yang, Jinho, Kim, Jong-kyu, Kim, Hyun Goo, Paek, Se Hyun, Lee, Jun Woo, Woo, Joohyun, Kim, Jong Bin, Kwon, Hyungju, Lim, Woosung, Paik, Nam Sun, Kim, Yoon-Keun, Moon, Byung-In, Janku, Filip, Tan, David, Martin-Liberal, Juan, Takahashi, Shunji, Geva, Ravit, Gucalp, Ayca, Chen, Xueying, Subramanian, Kulandayan, Mataraza, Jennifer, Wheler, Jennifer, Bedard, Philippe
Publicado 2019