Alteration of the unfolded protein response modifies neurodegeneration in a mouse model of Marinesco–Sjögren syndrome

por Zhao, Lihong, Rosales, Christine, Seburn, Kevin, Ron, David, Ackerman, Susan L.
Publicado 2010

Defects in translation-dependent quality control pathways lead to convergent molecular and neurodevelopmental pathology

por Terrey, Markus, Adamson, Scott I, Chuang, Jeffrey H, Ackerman, Susan L
Publicado 2021

Activation of GCN2 kinase by ribosome stalling links translation elongation with translation initiation

por Ishimura, Ryuta, Nagy, Gabor, Dotu, Ivan, Chuang, Jeffrey H, Ackerman, Susan L
Publicado 2016

The Clp1 R140H mutation alters tRNA metabolism and mRNA 3′ processing in mouse models of pontocerebellar hypoplasia

por Monaghan, Caitlin E., Adamson, Scott I., Kapur, Mridu, Chuang, Jeffrey H., Ackerman, Susan L.
Publicado 2021

Regulation of ex-translational activities is the primary function of the multi-tRNA synthetase complex

por Cui, Haissi, Kapur, Mridu, Diedrich, Jolene K, Yates, John R, Ackerman, Susan L, Schimmel, Paul
Publicado 2020

GTPBP1 resolves paused ribosomes to maintain neuronal homeostasis

por Terrey, Markus, Adamson, Scott I, Gibson, Alana L, Deng, Tianda, Ishimura, Ryuta, Chuang, Jeffrey H, Ackerman, Susan L
Publicado 2020

Correction: GTPBP1 resolves paused ribosomes to maintain neuronal homeostasis

por Terrey, Markus, Adamson, Scott I, Gibson, Alana L, Deng, Tianda, Ishimura, Ryuta, Chuang, Jeffrey H, Ackerman, Susan L
Publicado 2021

Unc5C and DCC act downstream of Ctip2 and Satb2 and contribute to corpus callosum formation

por Srivatsa, Swathi, Parthasarathy, Srinivas, Britanova, Olga, Bormuth, Ingo, Donahoo, Amber-Lee, Ackerman, Susan L., Richards, Linda J., Tarabykin, Victor
Publicado 2014

Analysis of Expression Pattern and Genetic Deletion of Netrin5 in the Developing Mouse

por Garrett, Andrew M., Jucius, Thomas J., Sigaud, Liam P. R., Tang, Fu-Lei, Xiong, Wen-Cheng, Ackerman, Susan L., Burgess, Robert W.
Publicado 2016

Structural basis for impaired 5′ processing of a mutant tRNA associated with defects in neuronal homeostasis

por Lai, Lien B., Lai, Stella M., Szymanski, Eric S., Kapur, Mridu, Choi, Edric K., Al-Hashimi, Hashim M., Ackerman, Susan L., Gopalan, Venkat
Publicado 2022

A Deficiency of Ceramide Biosynthesis Causes Cerebellar Purkinje Cell Neurodegeneration and Lipofuscin Accumulation

por Zhao, Lihong, Spassieva, Stefka D., Jucius, Thomas J., Shultz, Leonard D., Shick, H. Elizabeth, Macklin, Wendy B., Hannun, Yusuf A., Obeid, Lina M., Ackerman, Susan L.
Publicado 2011

Synergistic integration of Netrin and ephrin axon guidance signals by spinal motor neurons

por Poliak, Sebastian, Morales, Daniel, Croteau, Louis-Philippe, Krawchuk, Dayana, Palmesino, Elena, Morton, Susan, Cloutier, Jean-François, Charron, Frederic, Dalva, Matthew B, Ackerman, Susan L, Kao, Tzu-Jen, Kania, Artur
Publicado 2015

ANKRD16 prevents neuron loss caused by an editing-defective tRNA synthetase

por Vo, My-Nuong, Terrey, Markus, Lee, Jeong Woong, Roy, Bappaditya, Moresco, James J., Sun, Litao, Fu, Hongjun, Liu, Qi, Weber, Thomas G., Yates, John R., Fredrick, Kurt, Schimmel, Paul, Ackerman, Susan L.
Publicado 2018

Endothelial Unc5B controls blood-brain barrier integrity

por Boyé, Kevin, Geraldo, Luiz Henrique, Furtado, Jessica, Pibouin-Fragner, Laurence, Poulet, Mathilde, Kim, Doyeun, Nelson, Bryce, Xu, Yunling, Jacob, Laurent, Maissa, Nawal, Agalliu, Dritan, Claesson-Welsh, Lena, Ackerman, Susan L., Eichmann, Anne
Publicado 2022

Seryl-tRNA synthetase promotes translational readthrough by mRNA binding and involvement of the selenocysteine incorporation machinery

por Liu, Ze, Wang, Justin, Shi, Yi, Yee, Brian A, Terrey, Markus, Zhang, Qian, Lee, Jenq-Chang, Lin, Kuo-I, Wang, Andrew H-J, Ackerman, Susan L, Yeo, Gene W, Cui, Haissi, Yang, Xiang-Lei
Publicado 2023