Structural and dynamic changes in P-Rex1 upon activation by PIP(3) and inhibition by IP(4)

por Ravala, Sandeep K., Adame-Garcia, Sendi Rafael, Li, Sheng, Chen, Chun-Liang, Cianfrocco, Michael A., Gutkind, J. Silvio, Cash, Jennifer N., Tesmer, John J. G.
Publicado 2023

Focal Adhesion Kinase (FAK)-Hippo/YAP transduction signaling mediates the stimulatory effects exerted by S100A8/A9-RAGE system in triple-negative breast cancer (TNBC)

por Rigiracciolo, Damiano Cosimo, Nohata, Nijiro, Lappano, Rosamaria, Cirillo, Francesca, Talia, Marianna, Adame-Garcia, Sendi Rafael, Arang, Nadia, Lubrano, Simone, De Francesco, Ernestina Marianna, Belfiore, Antonino, Gutkind, J. Silvio, Maggiolini, Marcello
Publicado 2022

Gαs is dispensable for β-arrestin coupling but dictates GRK selectivity and is predominant for gene expression regulation by β2-adrenergic receptor

por Burghi, Valeria, Paradis, Justine S., Officer, Adam, Adame-Garcia, Sendi Rafael, Wu, Xingyu, Matthees, Edda S.F., Barsi-Rhyne, Benjamin, Ramms, Dana J., Clubb, Lauren, Acosta, Monica, Tamayo, Pablo, Bouvier, Michel, Inoue, Asuka, von Zastrow, Mark, Hoffmann, Carsten, Gutkind, J. Silvio
Publicado 2023