Inventing new medicines: The FGF21 story()

por Kharitonenkov, Alexei, Adams, Andrew C.
Publicado 2013

FGF21 Requires βklotho to Act In Vivo

por Adams, Andrew C., Cheng, Christine C., Coskun, Tamer, Kharitonenkov, Alexei
Publicado 2012

Fibroblast Growth Factor 21 Is Not Required for the Reductions in Circulating Insulin-Like Growth Factor-1 or Global Cell Proliferation Rates in Response to Moderate Calorie Restri...

por Thompson, Airlia C. S., Bruss, Matthew D., Nag, Nitish, Kharitonenkov, Alexei, Adams, Andrew C., Hellerstein, Marc K.
Publicado 2014

Neutralizing monoclonal antibodies for treatment of COVID-19

por Taylor, Peter C., Adams, Andrew C., Hufford, Matthew M., de la Torre, Inmaculada, Winthrop, Kevin, Gottlieb, Robert L.
Publicado 2021

Fibroblast growth factor 21 has no direct role in regulating fertility in female mice

por Singhal, Garima, Douris, Nicholas, Fish, Alan J., Zhang, Xinyao, Adams, Andrew C., Flier, Jeffrey S., Pissios, Pavlos, Maratos-Flier, Eleftheria
Publicado 2016

Reduced adiposity attenuates FGF21 mediated metabolic improvements in the Siberian hamster

por Lewis, Jo E., Samms, Ricardo J., Cooper, Scott, Luckett, Jeni C., Perkins, Alan C., Adams, Andrew C., Tsintzas, Kostas, Ebling, Francis J. P.
Publicado 2017

Fundamentals of FGF19 & FGF21 Action In Vitro and In Vivo

por Adams, Andrew C., Coskun, Tamer, Irizarry Rovira, Armando R., Schneider, Michael A., Raches, David W., Micanovic, Radmila, Bina, Holly A., Dunbar, James D., Kharitonenkov, Alexei
Publicado 2012

LY2405319, an Engineered FGF21 Variant, Improves the Metabolic Status of Diabetic Monkeys

por Adams, Andrew C., Halstead, Carolyn A., Hansen, Barbara C., Irizarry, Armando R., Martin, Jennifer A., Myers, Sharon R., Reynolds, Vincent L., Smith, Holly W., Wroblewski, Victor J., Kharitonenkov, Alexei
Publicado 2013

Fibroblast Growth Factor 21 (FGF21) Protects against High Fat Diet Induced Inflammation and Islet Hyperplasia in Pancreas

por Singhal, Garima, Fisher, ffolliott Martin, Chee, Melissa J., Tan, Tze Guan, El Ouaamari, Abdelfattah, Adams, Andrew C., Najarian, Robert, Kulkarni, Rohit N., Benoist, Christophe, Flier, Jeffrey S., Maratos-Flier, Eleftheria
Publicado 2016

The anti-obesity effect of FGF19 does not require UCP1-dependent thermogenesis

por Antonellis, Patrick J., Droz, Brian A., Cosgrove, Richard, O'Farrell, Libbey S., Coskun, Tamer, Perfield, James W., Bauer, Steven, Wade, Mark, Chouinard, Tara E., Brozinick, Joseph T., Adams, Andrew C., Samms, Ricardo J.
Publicado 2019

Serum FGF21 levels are associated with brown adipose tissue activity in humans

por Hanssen, Mark J.W., Broeders, Evie, Samms, Ricardo J., Vosselman, Maarten J., van der Lans, Anouk A.J.J., Cheng, Christine C., Adams, Andrew C., van Marken Lichtenbelt, Wouter D., Schrauwen, Patrick
Publicado 2015

Antibody-Mediated Targeting of the FGFR1c Isoform Increases Glucose Uptake in White and Brown Adipose Tissue in Male Mice

por Lewis, Jo E., Samms, Ricardo J., Cooper, Scott, Luckett, Jeni C., Perkins, Alan C., Dunbar, James D., Smith, Dennis P., Emmerson, Paul J., Adams, Andrew C., Ebling, Francis J. P., Tsintzas, Kostas
Publicado 2017

Whole-body and adipose tissue-specific mechanisms underlying the metabolic effects of fibroblast growth factor 21 in the Siberian hamster

por Lewis, Jo E., Monnier, Chloe, Marshall, Hayley, Fowler, Maxine, Green, Rebecca, Cooper, Scott, Chiotellis, Aristeidis, Luckett, Jeni, Perkins, Alan C., Coskun, Tamer, Adams, Andrew C., Samms, Ricardo J., Ebling, Francis J.P., Tsintzas, Kostas
Publicado 2019

The Promyelocytic Leukemia Protein Is Upregulated in Conditions of Obesity and Liver Steatosis

por Carracedo, Arkaitz, Rousseau, Déborah, Douris, Nicholas, Fernández-Ruiz, Sonia, Martín-Martín, Natalia, Weiss, Dror, Webster, Kaitlyn, Adams, Andrew C., Vazquez-Chantada, Mercedes, Martinez-Chantar, Maria L., Anty, Rodolphe, Tran, Albert, Maratos-Flier, Eleftheria, Gual, Philippe, Pandolfi, Pier Paolo
Publicado 2015

Fibroblast growth factor 21 (FGF21) is robustly induced by ethanol and has a protective role in ethanol associated liver injury

por Desai, Bhavna N., Singhal, Garima, Watanabe, Mikiko, Stevanovic, Darko, Lundasen, Thomas, Fisher, ffolliott M., Mather, Marie L., Vardeh, Hilde G., Douris, Nicholas, Adams, Andrew C., Nasser, Imad A., FitzGerald, Garret A., Flier, Jeffrey S., Skarke, Carsten, Maratos-Flier, Eleftheria
Publicado 2017

CMPF, a Metabolite Formed Upon Prescription Omega-3-Acid Ethyl Ester Supplementation, Prevents and Reverses Steatosis

por Prentice, Kacey J., Wendell, Stacy G., Liu, Ying, Eversley, Judith A., Salvatore, Sonia R., Mohan, Haneesha, Brandt, Sydney L., Adams, Andrew C., Serena Wang, X., Wei, David, FitzGerald, Garret A., Durham, Timothy B., Hammond, Craig D., Sloop, Kyle W., Skarke, Carsten, Schopfer, Francisco J., Wheeler, Michael B.
Publicado 2017

SARS-CoV-2 Neutralizing Antibody LY-CoV555 in Outpatients with Covid-19

por Chen, Peter, Nirula, Ajay, Heller, Barry, Gottlieb, Robert L., Boscia, Joseph, Morris, Jason, Huhn, Gregory, Cardona, Jose, Mocherla, Bharat, Stosor, Valentina, Shawa, Imad, Adams, Andrew C., Van Naarden, Jacob, Custer, Kenneth L., Shen, Lei, Durante, Michael, Oakley, Gerard, Schade, Andrew E., Sabo, Janelle, Patel, Dipak R., Klekotka, Paul, Skovronsky, Daniel M.
Publicado 2020

Bamlanivimab plus Etesevimab in Mild or Moderate Covid-19

por Dougan, Michael, Nirula, Ajay, Azizad, Masoud, Mocherla, Bharat, Gottlieb, Robert L., Chen, Peter, Hebert, Corey, Perry, Russell, Boscia, Joseph, Heller, Barry, Morris, Jason, Crystal, Chad, Igbinadolor, Awawu, Huhn, Gregory, Cardona, Jose, Shawa, Imad, Kumar, Princy, Adams, Andrew C., Van Naarden, Jacob, Custer, Kenneth L., Durante, Michael, Oakley, Gerard, Schade, Andrew E., Holzer, Timothy R., Ebert, Philip J., Higgs, Richard E., Kallewaard, Nicole L., Sabo, Janelle, Patel, Dipak R., Dabora, Matan C., Klekotka, Paul, Shen, Lei, Skovronsky, Daniel M.
Publicado 2021

A Randomized, Placebo-Controlled Clinical Trial of Bamlanivimab and Etesevimab Together in High-Risk Ambulatory Patients With COVID-19 and Validation of the Prognostic Value of Per...

por Dougan, Michael, Azizad, Masoud, Mocherla, Bharat, Gottlieb, Robert L, Chen, Peter, Hebert, Corey, Perry, Russell, Boscia, Joseph, Heller, Barry, Morris, Jason, Crystal, Chad, Igbinadolor, Awawu, Huhn, Gregory, Cardona, Jose, Shawa, Imad, Kumar, Princy, Blomkalns, Andra, Adams, Andrew C, Van Naarden, Jacob, Custer, Kenneth L, Knorr, Jack, Oakley, Gerard, Schade, Andrew E, Holzer, Timothy R, Ebert, Philip J, Higgs, Richard E, Sabo, Janelle, Patel, Dipak R, Dabora, Matan C, Williams, Mark, Klekotka, Paul, Shen, Lei, Skovronsky, Daniel M, Nirula, Ajay
Publicado 2021

The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates

por Jones, Bryan E., Brown-Augsburger, Patricia L., Corbett, Kizzmekia S., Westendorf, Kathryn, Davies, Julian, Cujec, Thomas P., Wiethoff, Christopher M., Blackbourne, Jamie L., Heinz, Beverly A., Foster, Denisa, Higgs, Richard E., Balasubramaniam, Deepa, Wang, Lingshu, Zhang, Yi, Yang, Eun Sung, Bidshahri, Roza, Kraft, Lucas, Hwang, Yuri, Žentelis, Stefanie, Jepson, Kevin R., Goya, Rodrigo, Smith, Maia A., Collins, David W., Hinshaw, Samuel J., Tycho, Sean A., Pellacani, Davide, Xiang, Ping, Muthuraman, Krithika, Sobhanifar, Solmaz, Piper, Marissa H., Triana, Franz J., Hendle, Jorg, Pustilnik, Anna, Adams, Andrew C., Berens, Shawn J., Baric, Ralph S., Martinez, David R., Cross, Robert W., Geisbert, Thomas W., Borisevich, Viktoriya, Abiona, Olubukola, Belli, Hayley M., de Vries, Maren, Mohamed, Adil, Dittmann, Meike, Samanovic, Marie I., Mulligan, Mark J., Goldsmith, Jory A., Hsieh, Ching-Lin, Johnson, Nicole V., Wrapp, Daniel, McLellan, Jason S., Barnhart, Bryan C., Graham, Barney S., Mascola, John R., Hansen, Carl L., Falconer, Ester
Publicado 2021