Aging-Induced Stem Cell Mutations as Drivers for Disease and Cancer

por Adams, Peter D., Jasper, Heinrich, Rudolph, K. Lenhard
Publicado 2015

Critical Parameters for Efficient Sonication and Improved Chromatin Immunoprecipitation of High Molecular Weight Proteins

por Pchelintsev, Nikolay A., Adams, Peter D., Nelson, David M.
Publicado 2016

Serine Metabolism Supports the Methionine Cycle and DNA/RNA Methylation through De Novo ATP Synthesis in Cancer Cells

por Maddocks, Oliver D.K., Labuschagne, Christiaan F., Adams, Peter D., Vousden, Karen H.
Publicado 2016

Cytoplasmic chromatin fragments—from mechanisms to therapeutic potential

por Miller, Karl N, Dasgupta, Nirmalya, Liu, Tianhui, Adams, Peter D, Vizioli, Maria Grazia
Publicado 2021

Senescent mouse cells fail to overtly regulate the HIRA histone chaperone and do not form robust Senescence Associated Heterochromatin Foci

por Kennedy, Alyssa L, McBryan, Tony, Enders, Greg H, Johnson, F Brad, Zhang, Rugang, Adams, Peter D
Publicado 2010

Ubinuclein-1 confers histone H3.3-specific-binding by the HIRA histone chaperone complex

por Daniel Ricketts, M, Frederick, Brian, Hoff, Henry, Tang, Yong, Schultz, David C., Singh Rai, Taranjit, Grazia Vizioli, Maria, Adams, Peter D., Marmorstein, Ronen
Publicado 2015

A Role for p53 in the Adaptation to Glutamine Starvation through the Expression of SLC1A3

por Tajan, Mylène, Hock, Andreas K., Blagih, Julianna, Robertson, Neil A., Labuschagne, Christiaan F., Kruiswijk, Flore, Humpton, Timothy J., Adams, Peter D., Vousden, Karen H.
Publicado 2018

DNMT inhibitors reverse a specific signature of aberrant promoter DNA methylation and associated gene silencing in AML

por Lund, Kirstin, Cole, John J, VanderKraats, Nathan D, McBryan, Tony, Pchelintsev, Nikolay A, Clark, William, Copland, Mhairi, Edwards, John R, Adams, Peter D
Publicado 2014

Intergenerational inheritance of high fat diet-induced cardiac lipotoxicity in Drosophila

por Guida, Maria Clara, Birse, Ryan Tyge, Dall’Agnese, Alessandra, Toto, Paula Coutinho, Diop, Soda Balla, Mai, Antonello, Adams, Peter D., Puri, Pier Lorenzo, Bodmer, Rolf
Publicado 2019

Histone chaperone HIRA deposits histone H3.3 onto foreign viral DNA and contributes to anti-viral intrinsic immunity

por Rai, Taranjit Singh, Glass, Mandy, Cole, John J., Rather, Mohammad I., Marsden, Morgan, Neilson, Matthew, Brock, Claire, Humphreys, Ian R., Everett, Roger D., Adams, Peter D.
Publicado 2017

Epigenetic aging signatures in mice livers are slowed by dwarfism, calorie restriction and rapamycin treatment

por Wang, Tina, Tsui, Brian, Kreisberg, Jason F., Robertson, Neil A., Gross, Andrew M., Yu, Michael Ku, Carter, Hannah, Brown-Borg, Holly M., Adams, Peter D., Ideker, Trey
Publicado 2017

DNMT3B Oncogenic Activity in Human Intestinal Cancer Is Not Linked to CIMP or BRAFV600E Mutation

por MacKenzie, Douglas J., Robertson, Neil A., Rather, Iqbal, Reid, Claire, Sendzikaite, Gintare, Cruickshanks, Hazel, McBryan, Tony, Hodges, Andrew, Pritchard, Catrin, Blyth, Karen, Adams, Peter D.
Publicado 2020

Profiling of transcriptional and epigenetic changes during directed endothelial differentiation of human embryonic stem cells identifies FOXA2 as a marker of early mesoderm commitm...

por Howard, Lynsey, Mackenzie, Ruth M, Pchelintsev, Nikolay A, McBryan, Tony, McClure, John D, McBride, Martin W, Kane, Nicole M, Adams, Peter D, Milligan, Graeme, Baker, Andrew H
Publicado 2013

Lysosome-mediated processing of chromatin in senescence

por Ivanov, Andre, Pawlikowski, Jeff, Manoharan, Indrani, van Tuyn, John, Nelson, David M., Rai, Taranjit Singh, Shah, Parisha P., Hewitt, Graeme, Korolchuk, Viktor I., Passos, Joao F., Wu, Hong, Berger, Shelley L., Adams, Peter D.
Publicado 2013

The histone chaperone HIRA promotes the induction of host innate immune defences in response to HSV-1 infection

por McFarlane, Steven, Orr, Anne, Roberts, Ashley P. E., Conn, Kristen L., Iliev, Victor, Loney, Colin, da Silva Filipe, Ana, Smollett, Katherine, Gu, Quan, Robertson, Neil, Adams, Peter D., Rai, Taranjit Singh, Boutell, Chris
Publicado 2019

Notch Signaling Mediates Secondary Senescence

por Teo, Yee Voan, Rattanavirotkul, Nattaphong, Olova, Nelly, Salzano, Angela, Quintanilla, Andrea, Tarrats, Nuria, Kiourtis, Christos, Müller, Miryam, Green, Anthony R., Adams, Peter D., Acosta, Juan-Carlos, Bird, Thomas G., Kirschner, Kristina, Neretti, Nicola, Chandra, Tamir
Publicado 2019

Lamin B1 depletion in senescent cells triggers large-scale changes in gene expression and the chromatin landscape

por Shah, Parisha P., Donahue, Greg, Otte, Gabriel L., Capell, Brian C., Nelson, David M., Cao, Kajia, Aggarwala, Varun, Cruickshanks, Hazel A., Rai, Taranjit Singh, McBryan, Tony, Gregory, Brian D., Adams, Peter D., Berger, Shelley L.
Publicado 2013

MLL1 is essential for the senescence-associated secretory phenotype

por Capell, Brian C., Drake, Adam M., Zhu, Jiajun, Shah, Parisha P., Dou, Zhixun, Dorsey, Jean, Simola, Daniel F., Donahue, Greg, Sammons, Morgan, Rai, Taranjit Singh, Natale, Christopher, Ridky, Todd W., Adams, Peter D., Berger, Shelley L.
Publicado 2016

Oncogene-Expressing Senescent Melanocytes Up-Regulate MHC Class II, a Candidate Melanoma Suppressor Function

por van Tuyn, John, Jaber-Hijazi, Farah, MacKenzie, Douglas, Cole, John J., Mann, Elizabeth, Pawlikowski, Jeff S., Rai, Taranjit Singh, Nelson, David M., McBryan, Tony, Ivanov, Andre, Blyth, Karen, Wu, Hong, Milling, Simon, Adams, Peter D.
Publicado 2017

Imaging-based chromatin and epigenetic age, ImAge, quantitates aging and rejuvenation

por Alvarez-Kuglen, Martin, Rodriguez, Delany, Qin, Haodong, Ninomiya, Kenta, Fiengo, Lorenzo, Farhy, Chen, Hsu, Wei-Mien, Havas, Aaron, Feng, Gen-Sheng, Roberts, Amanda J., Anderson, Rozalyn M., Serrano, Manuel, Adams, Peter D., Sharpee, Tatyana O., Terskikh, Alexey V.
Publicado 2023