Drug repurposing and human parasitic protozoan diseases

por Andrews, Katherine T., Fisher, Gillian, Skinner-Adams, Tina S.
Publicado 2014

Activity of bromodomain protein inhibitors/binders against asexual-stage Plasmodium falciparum parasites

por Chua, Ming Jang, Robaa, Dina, Skinner-Adams, Tina S., Sippl, Wolfgang, Andrews, Katherine T.
Publicado 2018

An ELISA method to assess HDAC inhibitor-induced alterations to P. falciparum histone lysine acetylation

por Hesping, Eva, Skinner-Adams, Tina S., Fisher, Gillian M., Kurz, Thomas, Andrews, Katherine T.
Publicado 2020

Comparison of Plasmodium falciparum transfection methods

por Skinner-Adams, Tina S, Lawrie, Paula M, Hawthorne, Paula L, Gardiner, Donald L, Trenholme, Katharine R
Publicado 2003

Abstracts of the 2022 48th Annual NATAS Conference

por Adams, Tina, Schoch, Karl F., Pelczar, Elizabeth, Xia, Han, Hu, Xiao, Reynaud, Sara, Sauerbrunn, Stephen
Publicado 2022

A novel in vitro image-based assay identifies new drug leads for giardiasis

por Hart, Christopher J.S., Munro, Taylah, Andrews, Katherine T., Ryan, John H., Riches, Andrew G., Skinner-Adams, Tina S.
Publicado 2017

An image-based Pathogen Box screen identifies new compounds with anti-Giardia activity and highlights the importance of assay choice in phenotypic drug discovery

por Tiash, Snigdha, Saunders, Jake, Hart, Christopher J.S., Ryan, John H., Riches, Andrew G., Skinner-Adams, Tina S.
Publicado 2020

Synthesis and Antiplasmodial Evaluation of Analogues Based on the Tricyclic Core of Thiaplakortones A–D

por Schwartz, Brett D., Coster, Mark J., Skinner-Adams, Tina S., Andrews, Katherine T., White, Jonathan M., Davis, Rohan A.
Publicado 2015

Abstracts of the 2023 49th Annual NATAS Conference

por LaVan, David, Yi, Feng, Adams, Tina, Tao, Ran, Pelczar, Elizabeth, Xia, Han, Hu, Xiao, Sauerbrunn, Stephen, Matisons, Janis
Publicado 2023

A Subset Screen of the Compounds Australia Scaffold Library Identifies 7-Acylaminodibenzoxazepinones as Potent and Selective Hits for Anti-Giardia Drug Discovery

por Hart, Christopher J. S., Riches, Andrew G., Tiash, Snigdha, Clapper, Erin, Ramu, Soumya, Zuegg, Johannes, Ryan, John H., Skinner-Adams, Tina S.
Publicado 2022

Profiling the anti-protozoal activity of anti-cancer HDAC inhibitors against Plasmodium and Trypanosoma parasites

por Engel, Jessica A., Jones, Amy J., Avery, Vicky M., Sumanadasa, Subathdrage D.M., Ng, Susanna S., Fairlie, David P., Adams, Tina S., Andrews, Katherine T.
Publicado 2015

Erratum to “Profiling the anti-protozoal activity of anti-cancer HDAC inhibitors against Plasmodium and Trypanosoma parasites” [Int. J. Parasitol. Drugs Drug Res. 5 (2015) 117–126]...

por Engel, Jessica A., Jones, Amy J., Avery, Vicky M., Sumanadasa, Subathdrage D.M., Ng, Susanna S., Fairlie, David P., Skinner-Adams, Tina, Andrews, Katherine T.
Publicado 2016

Fingerprinting the Substrate Specificity of M1 and M17 Aminopeptidases of Human Malaria, Plasmodium falciparum

por Poreba, Marcin, McGowan, Sheena, Skinner-Adams, Tina S., Trenholme, Katharine R., Gardiner, Donald L., Whisstock, James C., To, Joyce, Salvesen, Guy S., Dalton, John P., Drag, Marcin
Publicado 2012

Effect of clinically approved HDAC inhibitors on Plasmodium, Leishmania and Schistosoma parasite growth

por Chua, Ming Jang, Arnold, Megan S.J., Xu, Weijun, Lancelot, Julien, Lamotte, Suzanne, Späth, Gerald F., Prina, Eric, Pierce, Raymond J., Fairlie, David P., Skinner-Adams, Tina S., Andrews, Katherine T.
Publicado 2016

Histone deacetylase inhibitor AR-42 and achiral analogues kill malaria parasites in vitro and in mice

por Chua, Ming Jang, Tng, Jiahui, Hesping, Eva, Fisher, Gillian M., Goodman, Christopher D., Skinner-Adams, Tina, Do, Darren, Lucke, Andrew J., Reid, Robert C., Fairlie, David P., Andrews, Katherine T.
Publicado 2021

Thieno[3,2-b]pyrrole 5-carboxamides as potent and selective inhibitors of Giardia duodenalis

por Hart, Christopher JS., Riches, Andrew G., Tiash, Snigdha, Abraham, Rebecca, Fayd’Herbe, Keely, Joch, Ellis, Zulfiqar, Bilal, Sykes, Melissa L., Avery, Vicky M., Šlapeta, Jan, Abraham, Sam, Ryan, John H., Skinner-Adams, Tina S.
Publicado 2023

The Frequency of Malaria Is Similar among Women Receiving either Lopinavir/Ritonavir or Nevirapine-based Antiretroviral Treatment

por Skinner-Adams, Tina S., Butterworth, Alice S., Porter, Kimberly A., D'Amico, Ronald, Sawe, Fred, Shaffer, Doug, Siika, Abraham, Hosseinipour, Mina C., Stringer, Elizabeth, Currier, Judith S., Chipato, Tsungai, Salata, Robert, Lockman, Shahin, Eron, Joseph J., Meshnick, Steven R., McCarthy, James S.
Publicado 2012

Cyclization-blocked proguanil as a strategy to improve the antimalarial activity of atovaquone

por Skinner-Adams, Tina S., Fisher, Gillian M., Riches, Andrew G., Hutt, Oliver E., Jarvis, Karen E., Wilson, Tony, von Itzstein, Mark, Chopra, Pradeep, Antonova-Koch, Yevgeniya, Meister, Stephan, Winzeler, Elizabeth A., Clarke, Mary, Fidock, David A., Burrows, Jeremy N., Ryan, John H., Andrews, Katherine T.
Publicado 2019

The Key Glycolytic Enzyme Phosphofructokinase Is Involved in Resistance to Antiplasmodial Glycosides

por Fisher, Gillian M., Cobbold, Simon A., Jezewski, Andrew, Carpenter, Emma F., Arnold, Megan, Cowell, Annie N., Tjhin, Erick T., Saliba, Kevin J., Skinner-Adams, Tina S., Lee, Marcus C. S., Odom John, Audrey, Winzeler, Elizabeth A., McConville, Malcolm J., Poulsen, Sally-Ann, Andrews, Katherine T.
Publicado 2020

Fragment-Based Screening of a Natural Product Library against 62 Potential Malaria Drug Targets Employing Native Mass Spectrometry

por Vu, Hoan, Pedro, Liliana, Mak, Tin, McCormick, Brendan, Rowley, Jessica, Liu, Miaomiao, Di Capua, Angela, Williams-Noonan, Billy, Pham, Ngoc B., Pouwer, Rebecca, Nguyen, Bao, Andrews, Katherine T., Skinner-Adams, Tina, Kim, Jessica, Hol, Wim G. J., Hui, Raymond, Crowther, Gregory J., Van Voorhis, Wesley C., Quinn, Ronald J.
Publicado 2018