MCPIP-1-Mediated Immunosuppression of Neutrophils Exacerbates Acute Bacterial Peritonitis and Liver Injury

por Lin, Jian, Lu, Zhanjun, Li, Gengfeng, Zhang, Cui, Lu, Huiying, Gao, Sheng, Zhu, Ruixin, Huang, Hailiang, Aden, Konrad, Wang, Jianhua, Cong, Yingzi, Wu, Huili, Liu, Zhanju
Publicado 2022

Distinct Longitudinal Changes in Immunoglobulin G N-Glycosylation Associate with Therapy Response in Chronic Inflammatory Diseases

por Štambuk, Jerko, Vučković, Frano, Habazin, Siniša, Hanić, Maja, Novokmet, Mislav, Nikolaus, Susanna, Tran, Florian, Schreiber, Stefan, Franke, Andre, Rosenstiel, Philip, Lauc, Gordan, Aden, Konrad, Pezer, Marija
Publicado 2022

Amino acid auxotrophies in human gut bacteria are linked to higher microbiome diversity and long-term stability

por Starke, Svenja, Harris, Danielle M. M., Zimmermann, Johannes, Schuchardt, Sven, Oumari, Mhmd, Frank, Derk, Bang, Corinna, Rosenstiel, Philip, Schreiber, Stefan, Frey, Norbert, Franke, Andre, Aden, Konrad, Waschina, Silvio
Publicado 2023

EP1272: DIETARY LIPIDS FUEL METABOLIC ENTERITIS IN CROHN'S DISEASE

por Schwärzler, Julian, Mayr, Lisa, Grabherr, Felix, Niederreiter, Lukas, Philipp, Maureen, Enrich, Barbara, Koch, Robert, Effenberger, Maria, Aden, Konrad, Rosenstiel, Philip, Blumberg, Richard S., Kaser, Arthur, Tilg, Herbert, Adolph, Timon E.
Publicado 2022

The SYSCID map: a graphical and computational resource of molecular mechanisms across rheumatoid arthritis, systemic lupus erythematosus and inflammatory bowel disease

por Acencio, Marcio Luis, Ostaszewski, Marek, Mazein, Alexander, Rosenstiel, Philip, Aden, Konrad, Mishra, Neha, Andersen, Vibeke, Sidiropoulos, Prodromos, Banos, Aggelos, Filia, Anastasia, Rahmouni, Souad, Finckh, Axel, Gu, Wei, Schneider, Reinhard, Satagopam, Venkata
Publicado 2023

NOD2 Influences Trajectories of Intestinal Microbiota Recovery After Antibiotic Perturbation

por Moltzau Anderson, Jacqueline, Lipinski, Simone, Sommer, Felix, Pan, Wei-Hung, Boulard, Olivier, Rehman, Ateequr, Falk-Paulsen, Maren, Stengel, Stephanie T., Aden, Konrad, Häsler, Robert, Bharti, Richa, Künzel, Sven, Baines, John F., Chamaillard, Mathias, Rosenstiel, Philip
Publicado 2020

Nitrogen-15 dynamic nuclear polarization of nicotinamide derivatives in biocompatible solutions

por Peters, Josh P., Brahms, Arne, Janicaud, Vivian, Anikeeva, Maria, Peschke, Eva, Ellermann, Frowin, Ferrari, Arianna, Hellmold, Dana, Held-Feindt, Janka, Kim, Na-mi, Meiser, Johannes, Aden, Konrad, Herges, Rainer, Hövener, Jan-Bernd, Pravdivtsev, Andrey N.
Publicado 2023

Uncoupling of mucosal gene regulation, mRNA splicing and adherent microbiota signatures in inflammatory bowel disease

por Häsler, Robert, Sheibani-Tezerji, Raheleh, Sinha, Anupam, Barann, Matthias, Rehman, Ateequr, Esser, Daniela, Aden, Konrad, Knecht, Carolin, Brandt, Berenice, Nikolaus, Susanna, Schäuble, Sascha, Kaleta, Christoph, Franke, Andre, Fretter, Christoph, Müller, Werner, Hütt, Marc-Thorsten, Krawczak, Michael, Schreiber, Stefan, Rosenstiel, Philip
Publicado 2017

Prdx4 limits caspase‐1 activation and restricts inflammasome‐mediated signaling by extracellular vesicles

por Lipinski, Simone, Pfeuffer, Steffen, Arnold, Philipp, Treitz, Christian, Aden, Konrad, Ebsen, Henriette, Falk‐Paulsen, Maren, Gisch, Nicolas, Fazio, Antonella, Kuiper, Jan, Luzius, Anne, Billmann‐Born, Susanne, Schreiber, Stefan, Nuñez, Gabriel, Beer, Hans‐Dietmar, Strowig, Till, Lamkanfi, Mohamed, Tholey, Andreas, Rosenstiel, Philip
Publicado 2019

Microbiomarkers in inflammatory bowel diseases: caveats come with caviar

por Sommer, Felix, Rühlemann, Malte Christoph, Bang, Corinna, Höppner, Marc, Rehman, Ateequr, Kaleta, Christoph, Schmitt-Kopplin, Phillippe, Dempfle, Astrid, Weidinger, Stephan, Ellinghaus, Eva, Krauss-Etschmann, Susanne, Schmidt-Arras, Dirk, Aden, Konrad, Schulte, Dominik, Ellinghaus, David, Schreiber, Stefan, Tholey, Andreas, Rupp, Jan, Laudes, Matthias, Baines, John F, Rosenstiel, Philip, Franke, Andre
Publicado 2017

Signatures of TOP1 transcription-associated mutagenesis in cancer and germline

por Reijns, Martin A. M., Parry, David A., Williams, Thomas C., Nadeu, Ferran, Hindshaw, Rebecca L., Rios Szwed, Diana O., Nicholson, Michael D., Carroll, Paula, Boyle, Shelagh, Royo, Romina, Cornish, Alex J., Xiang, Hang, Ridout, Kate, Schuh, Anna, Aden, Konrad, Palles, Claire, Campo, Elias, Stankovic, Tatjana, Taylor, Martin S., Jackson, Andrew P.
Publicado 2022

Publisher Correction: Signatures of TOP1 transcription-associated mutagenesis in cancer and germline

por Reijns, Martin A. M., Parry, David A., Williams, Thomas C., Nadeu, Ferran, Hindshaw, Rebecca L., Rios Szwed, Diana O., Nicholson, Michael D., Carroll, Paula, Boyle, Shelagh, Royo, Romina, Cornish, Alex J., Xiang, Hang, Ridout, Kate, Schuh, Anna, Aden, Konrad, Palles, Claire, Campo, Elias, Stankovic, Tatjana, Taylor, Martin S., Jackson, Andrew P.
Publicado 2022

Longitudinal multi-omics analysis identifies early blood-based predictors of anti-TNF therapy response in inflammatory bowel disease

por Mishra, Neha, Aden, Konrad, Blase, Johanna I., Baran, Nathan, Bordoni, Dora, Tran, Florian, Conrad, Claudio, Avalos, Diana, Jaeckel, Charlot, Scherer, Michael, Sørensen, Signe B., Overgaard, Silja H., Schulte, Berenice, Nikolaus, Susanna, Rey, Guillaume, Gasparoni, Gilles, Lyons, Paul A., Schultze, Joachim L., Walter, Jörn, Andersen, Vibeke, Dermitzakis, Emmanouil T., Schreiber, Stefan, Rosenstiel, Philip
Publicado 2022

SETDB1 is required for intestinal epithelial differentiation and the prevention of intestinal inflammation

por Južnić, Lea, Peuker, Kenneth, Strigli, Anne, Brosch, Mario, Herrmann, Alexander, Häsler, Robert, Koch, Michael, Matthiesen, Liz, Zeissig, Yvonne, Löscher, Britt-Sabina, Nuber, Alexander, Schotta, Gunnar, Neumeister, Volker, Chavakis, Triantafyllos, Kurth, Thomas, Lesche, Mathias, Dahl, Andreas, von Mässenhausen, Anne, Linkermann, Andreas, Schreiber, Stefan, Aden, Konrad, Rosenstiel, Philip C, Franke, Andre, Hampe, Jochen, Zeissig, Sebastian
Publicado 2021

ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS–STING

por Aden, Konrad, Tran, Florian, Ito, Go, Sheibani-Tezerji, Raheleh, Lipinski, Simone, Kuiper, Jan W., Tschurtschenthaler, Markus, Saveljeva, Svetlana, Bhattacharyya, Joya, Häsler, Robert, Bartsch, Kareen, Luzius, Anne, Jentzsch, Marlene, Falk-Paulsen, Maren, Stengel, Stephanie T., Welz, Lina, Schwarzer, Robin, Rabe, Björn, Barchet, Winfried, Krautwald, Stefan, Hartmann, Gunther, Pasparakis, Manolis, Blumberg, Richard S., Schreiber, Stefan, Kaser, Arthur, Rosenstiel, Philip
Publicado 2018

DNA methyltransferase 3A controls intestinal epithelial barrier function and regeneration in the colon

por Fazio, Antonella, Bordoni, Dora, Kuiper, Jan W. P., Weber-Stiehl, Saskia, Stengel, Stephanie T., Arnold, Philipp, Ellinghaus, David, Ito, Go, Tran, Florian, Messner, Berith, Henning, Anna, Bernardes, Joana P., Häsler, Robert, Luzius, Anne, Imm, Simon, Hinrichsen, Finn, Franke, Andre, Huber, Samuel, Nikolaus, Susanna, Aden, Konrad, Schreiber, Stefan, Sommer, Felix, Natoli, Gioacchino, Mishra, Neha, Rosenstiel, Philip
Publicado 2022

A gut bacterial signature in blood and liver tissue characterizes cirrhosis and hepatocellular carcinoma

por Effenberger, Maria, Waschina, Silvio, Bronowski, Christina, Sturm, Gregor, Tassiello, Oronzo, Sommer, Felix, Zollner, Andreas, Watschinger, Christina, Grabherr, Felix, Gstir, Ronald, Grander, Christoph, Enrich, Barbara, Bale, Reto, Putzer, Daniel, Djanani, Angela, Moschen, Alexander R., Zoller, Heinz, Rupp, Jan, Schreiber, Stefan, Burcelin, Remy, Lass-Flörl, Cornelia, Trajanoski, Zlatko, Oberhuber, Georg, Rosenstiel, Philip, Adolph, Timon E., Aden, Konrad, Tilg, Herbert
Publicado 2023

Missense variants in NOX1 and p22phox in a case of very-early-onset inflammatory bowel disease are functionally linked to NOD2

por Lipinski, Simone, Petersen, Britt-Sabina, Barann, Matthias, Piecyk, Agnes, Tran, Florian, Mayr, Gabriele, Jentzsch, Marlene, Aden, Konrad, Stengel, Stephanie T., Klostermeier, Ulrich C., Sheth, Vrunda, Ellinghaus, David, Rausch, Tobias, Korbel, Jan O., Nothnagel, Michael, Krawczak, Michael, Gilissen, Christian, Veltman, Joris A., Forster, Michael, Forster, Peter, Lee, Clarence C., Fritscher-Ravens, Annette, Schreiber, Stefan, Franke, Andre, Rosenstiel, Philip
Publicado 2019

Epithelial RNase H2 Maintains Genome Integrity and Prevents Intestinal Tumorigenesis in Mice

por Aden, Konrad, Bartsch, Kareen, Dahl, Joseph, Reijns, Martin A.M., Esser, Daniela, Sheibani-Tezerji, Raheleh, Sinha, Anupam, Wottawa, Felix, Ito, Go, Mishra, Neha, Knittler, Katharina, Burkholder, Adam, Welz, Lina, van Es, Johan, Tran, Florian, Lipinski, Simone, Kakavand, Nassim, Boeger, Christine, Lucius, Ralph, von Schoenfels, Witigo, Schafmayer, Clemens, Lenk, Lennart, Chalaris, Athena, Clevers, Hans, Röcken, Christoph, Kaleta, Christoph, Rose-John, Stefan, Schreiber, Stefan, Kunkel, Thomas, Rabe, Björn, Rosenstiel, Philip
Publicado 2019

Selection of cross-reactive T cells by commensal and food-derived yeasts drives cytotoxic T(H)1 cell responses in Crohn’s disease

por Martini, Gabriela Rios, Tikhonova, Ekaterina, Rosati, Elisa, DeCelie, Meghan Bialt, Sievers, Laura Katharina, Tran, Florian, Lessing, Matthias, Bergfeld, Arne, Hinz, Sophia, Nikolaus, Susanna, Kümpers, Julia, Matysiak, Anna, Hofmann, Philipp, Saggau, Carina, Schneiders, Stephan, Kamps, Ann-Kristin, Jacobs, Gunnar, Lieb, Wolfgang, Maul, Jochen, Siegmund, Britta, Seegers, Barbara, Hinrichsen, Holger, Oberg, Hans-Heinrich, Wesch, Daniela, Bereswill, Stefan, Heimesaat, Markus M., Rupp, Jan, Kniemeyer, Olaf, Brakhage, Axel A., Brunke, Sascha, Hube, Bernhard, Aden, Konrad, Franke, Andre, Iliev, Iliyan D., Scheffold, Alexander, Schreiber, Stefan, Bacher, Petra
Publicado 2023