CRISPR-Cas9 Library Screening Identifies Novel Molecular Vulnerabilities in KMT2A-Rearranged Acute Lymphoblastic Leukemia

por Schneider, Pauline, Wander, Priscilla, Arentsen-Peters, Susan T. C. J. M., Vrenken, Kirsten S., Rockx-Brouwer, Dedeke, Adriaanse, Fabienne R. S., Hoeve, Veerle, Paassen, Irene, Drost, Jarno, Pieters, Rob, Stam, Ronald W.
Publicado 2023

Modelling acquired resistance to DOT1L inhibition exhibits the adaptive potential of KMT2A-rearranged acute lymphoblastic leukemia

por Schneider, Pauline, Crump, Nicholas T., Arentsen-Peters, Susan T.C.J.M., Smith, Alastair L., Hagelaar, Rico, Adriaanse, Fabienne R.S., Bos, Romy S., de Jong, Anja, Nierkens, Stefan, Koopmans, Bianca, Milne, Thomas A., Pieters, Rob, Stam, Ronald W.
Publicado 2023

A convergent malignant phenotype in B-cell acute lymphoblastic leukemia involving the splicing factor SRRM1

por Closa, Adria, Reixachs-Solé, Marina, Fuentes-Fayos, Antonio C, Hayer, Katharina E, Melero, Juan L, Adriaanse, Fabienne R S, Bos, Romy S, Torres-Diz, Manuel, Hunger, Stephen P, Roberts, Kathryn G, Mullighan, Charles G, Stam, Ronald W, Thomas-Tikhonenko, Andrei, Castaño, Justo P, Luque, Raúl M, Eyras, Eduardo
Publicado 2022