The Bidirectional Relationship Between Cancer Epigenetics and Metabolism

por Izzo, Luke T., Affronti, Hayley C., Wellen, Kathryn E.
Publicado 2020

Dynamic patterns of DNA methylation in the normal prostate epithelial differentiation program are targets of aberrant methylation in prostate cancer

por Long, Mark D., Dhiman, Vineet K., Affronti, Hayley C., Hu, Qiang, Liu, Song, Smiraglia, Dominic J.
Publicado 2021

JAZF1: A Metabolic Regulator of Sensitivity to a Polyamine-Targeted Therapy

por Rosario, Spencer R., Jacobi, Justine J., Long, Mark D., Affronti, Hayley C., Rowsam, Aryn M., Smiraglia, Dominic J.
Publicado 2023

Metastatic phenotype in CWR22 prostate cancer xenograft following castration

por Seedhouse, Steven J., Affronti, Hayley C., Karasik, Ellen, Gillard, Bryan M., Azabdaftari, Gissou, Smiraglia, Dominic J., Foster, Barbara A.
Publicado 2015

The essential role of methylthioadenosine phosphorylase in prostate cancer

por Bistulfi, Gaia, Affronti, Hayley C., Foster, Barbara A., Karasik, Ellen, Gillard, Bryan, Morrison, Carl, Mohler, James, Phillips, James G., Smiraglia, Dominic J.
Publicado 2016

Glutamine deprivation triggers NAGK-dependent hexosamine salvage

por Campbell, Sydney, Mesaros, Clementina, Izzo, Luke, Affronti, Hayley, Noji, Michael, Schaffer, Bethany E, Tsang, Tiffany, Sun, Kathryn, Trefely, Sophie, Kruijning, Salisa, Blenis, John, Blair, Ian A, Wellen, Kathryn E
Publicado 2021

Adipocyte ACLY Facilitates Dietary Carbohydrate Handling to Maintain Metabolic Homeostasis in Females

por Fernandez, Sully, Viola, John M., Torres, AnnMarie, Wallace, Martina, Trefely, Sophie, Zhao, Steven, Affronti, Hayley C., Gengatharan, Jivani M., Guertin, David A., Snyder, Nathaniel W., Metallo, Christian M., Wellen, Kathryn E.
Publicado 2019

Dietary folate levels alter the kinetics and molecular mechanism of prostate cancer recurrence in the CWR22 model

por Affronti, Hayley C., Long, Mark D., Rosario, Spencer R., Gillard, Bryan M., Karasik, Ellen, Boerlin, Christoph S., Pellerite, Anthony J., Foster, Barbara A., Attwood, Kristopher, Pili, Roberto, Wilton, John H., Campbell, Moray J., Smiraglia, Dominic J.
Publicado 2017

Reduced NCOR2 expression accelerates androgen deprivation therapy failure in prostate cancer

por Long, Mark D., Jacobi, Justine J., Singh, Prashant K., Llimos, Gerard, Wani, Sajad A., Rowsam, Aryn M., Rosario, Spencer R., Hoogstraat, Marlous, Linder, Simon, Kirk, Jason, Affronti, Hayley C., Bergman, Andries, Zwart, Wilbert, Campbell, Moray J., Smiraglia, Dominic J.
Publicado 2021

Acetylcarnitine shuttling links mitochondrial metabolism to histone acetylation and lipogenesis

por Izzo, Luke T., Trefely, Sophie, Demetriadou, Christina, Drummond, Jack M., Mizukami, Takuya, Kuprasertkul, Nina, Farria, Aimee T., Nguyen, Phuong T. T., Murali, Nivitha, Reich, Lauren, Kantner, Daniel S., Shaffer, Joshua, Affronti, Hayley, Carrer, Alessandro, Andrews, Andrew, Capell, Brian C., Snyder, Nathaniel W., Wellen, Kathryn E.
Publicado 2023

Internally ratiometric fluorescent sensors for evaluation of intracellular GTP levels and distribution

por Bianchi-Smiraglia, Anna, Rana, Mitra S., Foley, Colleen E., Paul, Leslie M., Lipchick, Brittany C., Moparthy, Sudha, Moparthy, Kalyana, Fink, Emily E., Bagati, Archis, Hurley, Edward, Affronti, Hayley C., Bakin, Andrei V., Kandel, Eugene S., Smiraglia, Dominic J., Feltri, Maria Laura, Sousa, Rui, Nikiforov, Mikhail A.
Publicado 2017

Pharmacological polyamine catabolism upregulation with methionine salvage pathway inhibition as an effective prostate cancer therapy

por Affronti, Hayley C., Rowsam, Aryn M., Pellerite, Anthony J., Rosario, Spencer R., Long, Mark D., Jacobi, Justine J., Bianchi-Smiraglia, Anna, Boerlin, Christoph S., Gillard, Bryan M., Karasik, Ellen, Foster, Barbara A., Moser, Michael, Wilton, John H., Attwood, Kristopher, Nikiforov, Mikhail A., Azabdaftari, Gissou, Pili, Roberto, Phillips, James G., Casero, Robert A., Smiraglia, Dominic J.
Publicado 2020

Lactate supports a metabolic-epigenetic link in macrophage polarization

por Noe, Jordan T., Rendon, Beatriz E., Geller, Anne E., Conroy, Lindsey R., Morrissey, Samantha M., Young, Lyndsay E.A., Bruntz, Ronald C., Kim, Eun J., Wise-Mitchell, Ashley, Barbosa de Souza Rizzo, Mariana, Relich, Eric R., Baby, Becca V., Johnson, Lance A., Affronti, Hayley C., McMasters, Kelly M., Clem, Brian F., Gentry, Matthew S., Yan, Jun, Wellen, Kathryn E., Sun, Ramon C., Mitchell, Robert A.
Publicado 2021