Dual-Target Mycobacterium tuberculosis Inhibition: Insights into the Molecular Mechanism of Antifolate Drugs

por Ramharack, Pritika, Salifu, Elliasu Y., Agoni, Clement
Publicado 2023

Allosteric inhibition induces an open WPD-loop: a new avenue towards glioblastoma therapy

por Agoni, Clement, Ramharack, Pritika, Soliman, Mahmoud E. S.
Publicado 2018

Modelling the Transitioning of SARS-CoV-2 nsp3 and nsp4 Lumenal Regions towards a More Stable State on Complex Formation

por Klatte, Nele, Shields, Denis C., Agoni, Clement
Publicado 2022

Repurposing antiviral phytochemicals from the leaf extracts of Spondias mombin (Linn) towards the identification of potential SARSCOV-2 inhibitors

por Boadu, Akwasi, Agoni, Clement, Karpoormath, Rajshekhar, Soliman, Mahmoud, Nlooto, Manimbulu
Publicado 2022

Identification of potential SARS-CoV-2 inhibitors from South African medicinal plant extracts using molecular modelling approaches

por Dwarka, Depika, Agoni, Clement, Mellem, John Jason, Soliman, Mahmoud E, Baijnath, Himansu
Publicado 2020

Assessment of urogenital schistosomiasis among basic school children in selected communities along major rivers in the central region of Ghana

por Duah, Evans, Kenu, Ernest, Adela, Edward Morkporkpor, Halm, Hilda Adjoa, Agoni, Clement, Kumi, Ransford Oduro
Publicado 2021

Normal Non-HDL Cholesterol, Low Total Cholesterol, and HDL Cholesterol Levels in Sickle Cell Disease Patients in the Steady State: A Case-Control Study of Tema Metropolis

por Ephraim, Richard K. D., Adu, Patrick, Ake, Edem, Agbodzakey, Hope, Adoba, Prince, Cudjoe, Obed, Agoni, Clement
Publicado 2016

Artificial Intelligence, Machine Learning, and Big Data for Ebola Virus Drug Discovery

por Kwofie, Samuel K., Adams, Joseph, Broni, Emmanuel, Enninful, Kweku S., Agoni, Clement, Soliman, Mahmoud E. S., Wilson, Michael D.
Publicado 2023

Characterization of the binding of MRTX1133 as an avenue for the discovery of potential KRAS(G12D) inhibitors for cancer therapy

por Issahaku, Abdul Rashid, Mukelabai, Namutula, Agoni, Clement, Rudrapal, Mithun, Aldosari, Sahar M., Almalki, Sami G., Khan, Johra
Publicado 2022

Cell-Penetrating Milk-Derived Peptides with a Non-Inflammatory Profile

por Agoni, Clement, Stavropoulos, Ilias, Kirwan, Anna, Mysior, Margharitha M., Holton, Therese, Kranjc, Tilen, Simpson, Jeremy C., Roche, Helen M., Shields, Denis C.
Publicado 2023

Influenza Viruses: Harnessing the Crucial Role of the M2 Ion-Channel and Neuraminidase toward Inhibitor Design

por Mtambo, Sphamadla E., Amoako, Daniel G., Somboro, Anou M., Agoni, Clement, Lawal, Monsurat M., Gumede, Nelisiwe S., Khan, Rene B., Kumalo, Hezekiel M.
Publicado 2021

Replacement of Chalcone-Ethers with Chalcone-Thioethers as Potent and Highly Selective Monoamine Oxidase-B Inhibitors and Their Protein-Ligand Interactions

por Mathew, Bijo, Oh, Jong Min, Khames, Ahmed, Abdelgawad, Mohamed A., Rangarajan, T. M., Nath, Lekshmi R., Agoni, Clement, Soliman, Mahmoud E. S., Mathew, Githa Elizabeth, Kim, Hoon
Publicado 2021

Novel Sunifiram-carbamate hybrids as potential dual acetylcholinesterase inhibitor and NMDAR co-agonist: simulation-guided analogue design and pharmacological screening

por Agha, Khalid A., Abo-Dya, Nader E., Issahaku, Abdul Rashid, Agoni, Clement, Soliman, Mahmoud E. S., Abdel-Aal, Eatedal H., Abdel-Samii, Zakaria K., Ibrahim, Tarek S.
Publicado 2022

Conjugated Dienones from Differently Substituted Cinnamaldehyde as Highly Potent Monoamine Oxidase-B Inhibitors: Synthesis, Biochemistry, and Computational Chemistry

por Mathew, Bijo, Oh, Jong Min, Abdelgawad, Mohamed A., Khames, Ahmed, Ghoneim, Mohammed M., Kumar, Sunil, Nath, Lekshmi R., Sudevan, Sachithra Thazhathuveedu, Parambi, Della Grace Thomas, Agoni, Clement, Soliman, Mahmoud E. S., Kim, Hoon
Publicado 2022