Access to Chiral Diamine Derivatives through Stereoselective Cu-Catalyzed Reductive Coupling of Imines and Allenamides

por Agrawal, Toolika, Martin, Robert T., Collins, Stephen, Wilhelm, Zachary, Edwards, Mytia D., Gutierrez, Osvaldo, Sieber, Joshua D.
Publicado 2021

Expanding Access to Remdesivir via an Improved Pyrrolotriazine Synthesis: Supply Centered Synthesis

por Paymode, Dinesh J., Cardoso, Flavio S. P., Agrawal, Toolika, Tomlin, John W., Cook, Daniel W., Burns, Justina M., Stringham, Rodger W., Sieber, Joshua D., Gupton, B. Frank, Snead, David R.
Publicado 2020

Practical and Scalable Two-Step Process for 6-(2-Fluoro-4-nitrophenyl)-2-oxa-6-azaspiro[3.3]heptane: A Key Intermediate of the Potent Antibiotic Drug Candidate TBI-223

por Cardoso, Flavio S.P., Kadam, Appasaheb L., Nelson, Ryan C., Tomlin, John W., Dahal, Dipendra, Kuehner, Christopher S., Gudvangen, Gard, Arduengo, Anthony J., Burns, Justina M., Aleshire, Sarah L., Snead, David R., Qu, Fengrui, Belmore, Ken, Ahmad, Saeed, Agrawal, Toolika, Sieber, Joshua D., Donsbach, Kai Oliver
Publicado 2023

Development of a Practical Synthesis of the 8-FDC Fragment of OPC-167832

por Gopalsamuthiram, Vijayagopal, Ho, Dang Binh, Peck, Cheryl L., Natarajan, Vasudevan, Agrawal, Toolika, Burns, Justina M., Bachert, John, Cook, Daniel W., Stringham, Rodger W., Nelson, Ryan, Ahmad, Saeed, Gupton, B. Frank, Snead, David R., McQuade, D. Tyler, Vaidyanathan, Rajappa, Donsbach, Kai, Sieber, Joshua D.
Publicado 2022