Skeletal muscle PGC-1α1 reroutes kynurenine metabolism to increase energy efficiency and fatigue-resistance

por Agudelo, Leandro Z., Ferreira, Duarte M. S., Dadvar, Shamim, Cervenka, Igor, Ketscher, Lars, Izadi, Manizheh, Zhengye, Liu, Furrer, Regula, Handschin, Christoph, Venckunas, Tomas, Brazaitis, Marius, Kamandulis, Sigitas, Lanner, Johanna T., Ruas, Jorge L.
Publicado 2019

Neurturin is a PGC-1α1-controlled myokine that promotes motor neuron recruitment and neuromuscular junction formation

por Mills, Richard, Taylor-Weiner, Hermes, Correia, Jorge C., Agudelo, Leandro Z., Allodi, Ilary, Kolonelou, Christina, Martinez-Redondo, Vicente, Ferreira, Duarte M.S., Nichterwitz, Susanne, Comley, Laura H., Lundin, Vanessa, Hedlund, Eva, Ruas, Jorge L., Teixeira, Ana I.
Publicado 2017

Bioenergetic cues shift FXR splicing towards FXRα2 to modulate hepatic lipolysis and fatty acid metabolism

por Correia, Jorge C., Massart, Julie, de Boer, Jan Freark, Porsmyr-Palmertz, Margareta, Martínez-Redondo, Vicente, Agudelo, Leandro Z., Sinha, Indranil, Meierhofer, David, Ribeiro, Vera, Björnholm, Marie, Sauer, Sascha, Dahlman-Wright, Karin, Zierath, Juleen R., Groen, Albert K., Ruas, Jorge L.
Publicado 2015

Single-cell dissection of the obesity-exercise axis in adipose-muscle tissues implies a critical role for mesenchymal stem cells

por Yang, Jiekun, Vamvini, Maria, Nigro, Pasquale, Ho, Li-Lun, Galani, Kyriakitsa, Alvarez, Marcus, Tanigawa, Yosuke, Renfro, Ashley, Carbone, Nicholas P., Laakso, Markku, Agudelo, Leandro Z., Pajukanta, Päivi, Hirshman, Michael F., Middelbeek, Roeland J.W., Grove, Kevin, Goodyear, Laurie J., Kellis, Manolis
Publicado 2022

LIM and cysteine-rich domains 1 (LMCD1) regulates skeletal muscle hypertrophy, calcium handling, and force

por Ferreira, Duarte M. S., Cheng, Arthur J., Agudelo, Leandro Z., Cervenka, Igor, Chaillou, Thomas, Correia, Jorge C., Porsmyr-Palmertz, Margareta, Izadi, Manizheh, Hansson, Alicia, Martínez-Redondo, Vicente, Valente-Silva, Paula, Pettersson-Klein, Amanda T., Estall, Jennifer L., Robinson, Matthew M., Nair, K. Sreekumaran, Lanner, Johanna T., Ruas, Jorge L.
Publicado 2019

Distinct metabolic programs established in the thymus control effector functions of γδ T cell subsets in tumor microenvironments

por Lopes, Noella, McIntyre, Claire, Martin, Stefania, Raverdeau, Mathilde, Sumaria, Nital, Kohlgruber, Ayano C., Fiala, Gina J., Agudelo, Leandro, Dyck, Lydia, Kane, Harry, Douglas, Aaron, Cunningham, Stephen, Prendeville, Hannah, Loftus, Roisin, Carmody, Colleen, Pierre, Philippe, Kellis, Manolis, Brenner, Michael, Argüello, Rafael J., Silva-Santos, Bruno, Pennington, Daniel J., Lynch, Lydia
Publicado 2021