Single-molecule analysis of a molecular disassemblase reveals the mechanism of Hsc70-driven clathrin uncoating

por Böcking, Till, Aguet, François, Harrison, Stephen C., Kirchhausen, Tomas
Publicado 2011

Local clustering of transferrin receptors promotes clathrin-coated pit initiation

por Liu, Allen P., Aguet, François, Danuser, Gaudenz, Schmid, Sandra L.
Publicado 2010

Phosphatidylinositol-(4,5)-bisphosphate regulates clathrin-coated pit initiation, stabilization, and size

por Antonescu, Costin N., Aguet, François, Danuser, Gaudenz, Schmid, Sandra L.
Publicado 2011

A vast resource of allelic expression data spanning human tissues

por Castel, Stephane E., Aguet, François, Mohammadi, Pejman, Ardlie, Kristin G., Lappalainen, Tuuli
Publicado 2020

A scalable unified framework of total and allele-specific counts for cis-QTL, fine-mapping, and prediction

por Liang, Yanyu, Aguet, François, Barbeira, Alvaro N., Ardlie, Kristin, Im, Hae Kyung
Publicado 2021

Modified penetrance of coding variants by cis-regulatory variation contributes to disease risk

por Castel, Stephane E., Cervera, Alejandra, Mohammadi, Pejman, Aguet, François, Reverter, Ferran, Wolman, Aaron, Guigo, Roderic, Iossifov, Ivan, Vasileva, Ana, Lappalainen, Tuuli
Publicado 2018

Scaling computational genomics to millions of individuals with GPUs

por Taylor-Weiner, Amaro, Aguet, François, Haradhvala, Nicholas J., Gosai, Sager, Anand, Shankara, Kim, Jaegil, Ardlie, Kristin, Van Allen, Eliezer M., Getz, Gad
Publicado 2019

Transcription factor regulation of eQTL activity across individuals and tissues

por Flynn, Elise D., Tsu, Athena L., Kasela, Silva, Kim-Hellmuth, Sarah, Aguet, Francois, Ardlie, Kristin G., Bussemaker, Harmen J., Mohammadi, Pejman, Lappalainen, Tuuli
Publicado 2022

Fine‐mapping and QTL tissue‐sharing information improves the reliability of causal gene identification

por Barbeira, Alvaro N., Melia, Owen J., Liang, Yanyu, Bonazzola, Rodrigo, Wang, Gao, Wheeler, Heather E., Aguet, François, Ardlie, Kristin G., Wen, Xiaoquan, Im, Hae K.
Publicado 2020

Placental RNA sequencing implicates IGFBP1 in insulin sensitivity during pregnancy and in gestational diabetes

por Hivert, Marie-France, White, Frederique, Allard, Catherine, James, Kaitlyn, Majid, Sana, Aguet, François, Ardlie, Kristin, Edlow, Andrea, Florez, Jose, Bouchard, Luigi, Jacques, Pierre-Etienne, Karumanchi, S., Powe, Camille
Publicado 2023

sn-spMF: matrix factorization informs tissue-specific genetic regulation of gene expression

por He, Yuan, Chhetri, Surya B., Arvanitis, Marios, Srinivasan, Kaushik, Aguet, François, Ardlie, Kristin G., Barbeira, Alvaro N., Bonazzola, Rodrigo, Im, Hae Kyung, Brown, Christopher D., Battle, Alexis
Publicado 2020

Leveraging supervised learning for functionally informed fine-mapping of cis-eQTLs identifies an additional 20,913 putative causal eQTLs

por Wang, Qingbo S., Kelley, David R., Ulirsch, Jacob, Kanai, Masahiro, Sadhuka, Shuvom, Cui, Ran, Albors, Carlos, Cheng, Nathan, Okada, Yukinori, Aguet, Francois, Ardlie, Kristin G., MacArthur, Daniel G., Finucane, Hilary K.
Publicado 2021

Massively-parallel single nucleus RNA-seq with DroNc-seq

por Habib, Naomi, Avraham-Davidi, Inbal, Basu, Anindita, Burks, Tyler, Shekhar, Karthik, Hofree, Matan, Choudhury, Sourav R., Aguet, François, Gelfand, Ellen, Ardlie, Kristin, Weitz, David A, Rozenblatt-Rosen, Orit, Zhang, Feng, Regev, Aviv
Publicado 2017

Multitissue H3K27ac profiling of GTEx samples links epigenomic variation to disease

por Hou, Lei, Xiong, Xushen, Park, Yongjin, Boix, Carles, James, Benjamin, Sun, Na, He, Liang, Patel, Aman, Zhang, Zhizhuo, Molinie, Benoit, Van Wittenberghe, Nicholas, Steelman, Scott, Nusbaum, Chad, Aguet, François, Ardlie, Kristin G., Kellis, Manolis
Publicado 2023

Single cell characterization of myeloma and its precursor conditions reveals transcriptional signatures of early tumorigenesis

por Boiarsky, Rebecca, Haradhvala, Nicholas J., Alberge, Jean-Baptiste, Sklavenitis-Pistofidis, Romanos, Mouhieddine, Tarek H., Zavidij, Oksana, Shih, Ming-Chieh, Firer, Danielle, Miller, Mendy, El-Khoury, Habib, Anand, Shankara K., Aguet, François, Sontag, David, Ghobrial, Irene M., Getz, Gad
Publicado 2022

Membrane dynamics of dividing cells imaged by lattice light-sheet microscopy

por Aguet, François, Upadhyayula, Srigokul, Gaudin, Raphaël, Chou, Yi-ying, Cocucci, Emanuele, He, Kangmin, Chen, Bi-Chang, Mosaliganti, Kishore, Pasham, Mithun, Skillern, Wesley, Legant, Wesley R., Liu, Tsung-Li, Findlay, Greg, Marino, Eric, Danuser, Gaudenz, Megason, Sean, Betzig, Eric, Kirchhausen, Tom
Publicado 2016

The landscape of expression and alternative splicing variation across human traits

por García-Pérez, Raquel, Ramirez, Jose Miguel, Ripoll-Cladellas, Aida, Chazarra-Gil, Ruben, Oliveros, Winona, Soldatkina, Oleksandra, Bosio, Mattia, Rognon, Paul Joris, Capella-Gutierrez, Salvador, Calvo, Miquel, Reverter, Ferran, Guigó, Roderic, Aguet, François, Ferreira, Pedro G., Ardlie, Kristin G., Melé, Marta
Publicado 2022

Impact of admixture and ancestry on eQTL analysis and GWAS colocalization in GTEx

por Gay, Nicole R., Gloudemans, Michael, Antonio, Margaret L., Abell, Nathan S., Balliu, Brunilda, Park, YoSon, Martin, Alicia R., Musharoff, Shaila, Rao, Abhiram S., Aguet, François, Barbeira, Alvaro N., Bonazzola, Rodrigo, Hormozdiari, Farhad, Ardlie, Kristin G., Brown, Christopher D., Im, Hae Kyung, Lappalainen, Tuuli, Wen, Xiaoquan, Montgomery, Stephen B.
Publicado 2020

Genetic Analysis in UK Biobank Links Insulin Resistance and Transendothelial Migration Pathways to Coronary Artery Disease

por Klarin, Derek, Zhu, Qiuyu Martin, Emdin, Connor A., Chaffin, Mark, Horner, Steven, McMillan, Brian J., Leed, Alison, Weale, Michael E., Spencer, Chris C. A., Aguet, François, Segrè, Ayellet V., Ardlie, Kristin G., Khera, Amit V., Kaushik, Virendar K., Natarajan, Pradeep, Consortium, CARDIoGRAMplusC4D, Kathiresan, Sekar
Publicado 2017

Landscape of X chromosome inactivation across human tissues

por Tukiainen, Taru, Villani, Alexandra-Chloé, Yen, Angela, Rivas, Manuel A., Marshall, Jamie L., Satija, Rahul, Aguirre, Matt, Gauthier, Laura, Fleharty, Mark, Kirby, Andrew, Cummings, Beryl B., Castel, Stephane E., Karczewski, Konrad J., Aguet, François, Byrnes, Andrea, Lappalainen, Tuuli, Regev, Aviv, Ardlie, Kristin G., Hacohen, Nir, MacArthur, Daniel G.
Publicado 2017