Immunotherapy and Immunochemotherapy in Visceral Leishmaniasis: Promising Treatments for this Neglected Disease

por Roatt, Bruno Mendes, Aguiar-Soares, Rodrigo Dian de Oliveira, Coura-Vital, Wendel, Ker, Henrique Gama, Moreira, Nádia das Dores, Vitoriano-Souza, Juliana, Giunchetti, Rodolfo Cordeiro, Carneiro, Cláudia Martins, Reis, Alexandre Barbosa
Publicado 2014

Prevalence and Factors Associated with Leishmania infantum Infection of Dogs from an Urban Area of Brazil as Identified by Molecular Methods

por Coura-Vital, Wendel, Marques, Marcos José, Veloso, Vanja Maria, Roatt, Bruno Mendes, Aguiar-Soares, Rodrigo Dian de Oliveira, Reis, Levi Eduardo Soares, Braga, Samuel Leôncio, Morais, Maria Helena Franco, Reis, Alexandre Barbosa, Carneiro, Mariângela
Publicado 2011

Liver infusion tryptose (LIT): the best choice for growth, viability, and infectivity of Leishmania infantum parasites

por Costa, Ana Flávia Pereira, de Brito, Rory Cristiane Fortes, Carvalho, Lívia Mendes, Cardoso, Jamille Mirelle de Oliveira, Vieira, Paula Melo de Abreu, Reis, Alexandre Barbosa, Aguiar-Soares, Rodrigo Dian de Oliveira, Roatt, Bruno Mendes
Publicado 2020

Heterologous vaccine therapy associated with half course of Miltefosine promote activation of the proinflammatory response with control of splenic parasitism in a hamster model of...

por Carvalho, Lívia Mendes, Ferreira, Francielle Carvalho, Gusmão, Miriã Rodrigues, Costa, Ana Flávia Pereira, de Brito, Rory Cristiane Fortes, Aguiar-Soares, Rodrigo Dian de Oliveira, Reis, Alexandre Barbosa, Cardoso, Jamille Mirelle de Oliveira, Carneiro, Cláudia Martins, Roatt, Bruno Mendes
Publicado 2021

Phase I and II Clinical Trial Comparing the LBSap, Leishmune(®), and Leish-Tec(®) Vaccines against Canine Visceral Leishmaniasis

por Aguiar-Soares, Rodrigo Dian de Oliveira, Roatt, Bruno Mendes, Mathias, Fernando Augusto Siqueira, Reis, Levi Eduardo Soares, Cardoso, Jamille Mirelle de Oliveira, de Brito, Rory Cristiane Fortes, Ker, Henrique Gama, Corrêa-Oliveira, Rodrigo, Giunchetti, Rodolfo Cordeiro, Reis, Alexandre Barbosa
Publicado 2020

The Use of an Adjuvant System Improves Innate and Adaptive Immune Response When Associated with a Leishmania (Viannia) braziliensis Antigen in a Vaccine Candidate against L. (Leish...

por Mathias, Fernando Augusto Siqueira, Ostolin, Thais Lopes Valentim Di Paschoale, Reis, Levi Eduardo Soares, Cardoso, Jamille Mirelle de Oliveira, De Brito, Rory Cristiane Fortes, Aguiar Soares, Rodrigo Dian de Oliveira, Roatt, Bruno Mendes, Vieira, Paula Melo de Abreu, Reis, Alexandre Barbosa
Publicado 2023

Performance of LBSap Vaccine after Intradermal Challenge with L. infantum and Saliva of Lu. longipalpis: Immunogenicity and Parasitological Evaluation

por Roatt, Bruno Mendes, Aguiar-Soares, Rodrigo Dian de Oliveira, Vitoriano-Souza, Juliana, Coura-Vital, Wendel, Braga, Samuel Leôncio, Corrêa-Oliveira, Rodrigo, Martins-Filho, Olindo Assis, Teixeira-Carvalho, Andréa, de Lana, Marta, Gontijo, Nelder Figueiredo, Marques, Marcos José, Giunchetti, Rodolfo Cordeiro, Reis, Alexandre Barbosa
Publicado 2012

Synthetic Peptides Elicit Strong Cellular Immunity in Visceral Leishmaniasis Natural Reservoir and Contribute to Long-Lasting Polyfunctional T-Cells in BALB/c Mice

por De Brito, Rory Cristiane Fortes, Cardoso, Jamille Mirelle de Oliveira, Reis, Levi Eduardo Soares, Mathias, Fernando Augusto Siqueira, Aguiar-Soares, Rodrigo Dian de Oliveira, Teixeira-Carvalho, Andréa, Roatt, Bruno Mendes, Corrêa-Oliveira, Rodrigo, Ruiz, Jeronimo Conceição, Resende, Daniela de Melo, Reis, Alexandre Barbosa
Publicado 2019

Cytokine and nitric oxide patterns in dogs immunized with LBSap vaccine, before and after experimental challenge with Leishmania chagasi plus saliva of Lutzomyia longipalpis

por Resende, Lucilene Aparecida, Roatt, Bruno Mendes, Aguiar-Soares, Rodrigo Dian de Oliveira, Viana, Kelvinson Fernandes, Mendonça, Ludmila Zanandreis, Lanna, Mariana Ferreira, Silveira-Lemos, Denise, Corrêa-Oliveira, Rodrigo, Martins-Filho, Olindo Assis, Fujiwara, Ricardo Toshio, Carneiro, Cláudia Martins, Reis, Alexandre Barbosa, Giunchetti, Rodolfo Cordeiro
Publicado 2013

Clinical Forms of Canine Visceral Leishmaniasis in Naturally Leishmania infantum–Infected Dogs and Related Myelogram and Hemogram Changes

por Nicolato, Roney de Carvalho, de Abreu, Raquel Trópia, Roatt, Bruno Mendes, Aguiar-Soares, Rodrigo Dian de Oliveira, Reis, Levi Eduardo Soares, Carvalho, Maria das Graças, Carneiro, Cláudia Martins, Giunchetti, Rodolfo Cordeiro, Bouillet, Leoneide Erica Maduro, Lemos, Denise Silveira, Coura-Vital, Wendel, Reis, Alexandre Barbosa
Publicado 2013

LBSapSal-vaccinated dogs exhibit increased circulating T-lymphocyte subsets (CD4(+) and CD8(+)) as well as a reduction of parasitism after challenge with Leishmania infantum plus s...

por Aguiar-Soares, Rodrigo Dian de Oliveira, Roatt, Bruno Mendes, Ker, Henrique Gama, Moreira, Nádia das Dores, Mathias, Fernando Augusto Siqueira, Cardoso, Jamille Mirelle de Oliveira, Gontijo, Nelder Figueiredo, Bruna-Romero, Oscar, Teixeira-Carvalho, Andréa, Martins-Filho, Olindo Assis, Corrêa-Oliveira, Rodrigo, Giunchetti, Rodolfo Cordeiro, Reis, Alexandre Barbosa
Publicado 2014

Chimeric Vaccines Designed by Immunoinformatics-Activated Polyfunctional and Memory T cells that Trigger Protection against Experimental Visceral Leishmaniasis

por De Brito, Rory Cristiane Fortes, Ruiz, Jeronimo Conceição, Cardoso, Jamille Mirelle de Oliveira, Ostolin, Thais Lopes Valentim Di Paschoale, Reis, Levi Eduardo Soares, Mathias, Fernando Augusto Siqueira, Aguiar-Soares, Rodrigo Dian de Oliveira, Roatt, Bruno Mendes, Corrêa-Oliveira, Rodrigo, Resende, Daniela de Melo, Reis, Alexandre Barbosa
Publicado 2020

Impact of LbSapSal Vaccine in Canine Immunological and Parasitological Features before and after Leishmania chagasi-Challenge

por Resende, Lucilene Aparecida, Aguiar-Soares, Rodrigo Dian de Oliveira, Gama-Ker, Henrique, Roatt, Bruno Mendes, de Mendonça, Ludmila Zanandreis, Alves, Marina Luiza Rodrigues, da Silveira-Lemos, Denise, Corrêa-Oliveira, Rodrigo, Martins-Filho, Olindo Assis, Araújo, Márcio Sobreira Silva, Fujiwara, Ricardo Toshio, Gontijo, Nelder Figueiredo, Reis, Alexandre Barbosa, Giunchetti, Rodolfo Cordeiro
Publicado 2016

A Vaccine Therapy for Canine Visceral Leishmaniasis Promoted Significant Improvement of Clinical and Immune Status with Reduction in Parasite Burden

por Roatt, Bruno Mendes, Aguiar-Soares, Rodrigo Dian de Oliveira, Reis, Levi Eduardo Soares, Cardoso, Jamille Mirelle de Oliveira, Mathias, Fernando Augusto Siqueira, de Brito, Rory Cristiane Fortes, da Silva, Sydnei Magno, Gontijo, Nelder De Figueiredo, Ferreira, Sidney de Almeida, Valenzuela, Jesus G., Corrêa-Oliveira, Rodrigo, Giunchetti, Rodolfo Cordeiro, Reis, Alexandre Barbosa
Publicado 2017

A killed Leishmania vaccine with sand fly saliva extract and saponin adjuvant displays immunogenicity in dogs

por Giunchetti, Rodolfo Cordeiro, Corrêa-Oliveira, Rodrigo, Martins-Filho, Olindo Assis, Teixeira-Carvalho, Andréa, Roatt, Bruno Mendes, Aguiar-Soares, Rodrigo Dian de Oliveira, Coura-Vital, Wendel, Abreu, Raquel Tropia de, Malaquias, Luiz Cosme Cotta, Gontijo, Nelder Figueiredo, Brodskyn, Cláudia, Oliveira, Camila Indiani de, Costa, Dirceu Joaquim, de Lana, Marta, Reis, Alexandre Barbosa
Publicado 2008

Multicomponent LBSap vaccine displays immunological and parasitological profiles similar to those of Leish-Tec® and Leishmune® vaccines against visceral leishmaniasis

por de Mendonça, Ludmila Zanandreis, Resende, Lucilene Aparecida, Lanna, Mariana Ferreira, Aguiar-Soares, Rodrigo Dian de Oliveira, Roatt, Bruno Mendes, Castro, Renata Alves de Oliveira e, Batista, Maurício Azevedo, Silveira-Lemos, Denise, Gomes, Juliana de Assis Silva, Fujiwara, Ricardo Toshio, Rezende, Simone Aparecida, Martins-Filho, Olindo Assis, Corrêa-Oliveira, Rodrigo, Dutra, Walderez Ornelas, Reis, Alexandre Barbosa, Giunchetti, Rodolfo Cordeiro
Publicado 2016

Kinetics of Phenotypic and Functional Changes in Mouse Models of Sponge Implants: Rational Selection to Optimize Protocols for Specific Biomolecules Screening Purposes

por Lanna, Mariana Ferreira, Resende, Lucilene Aparecida, Aguiar-Soares, Rodrigo Dian de Oliveira, de Miranda, Marina Barcelos, de Mendonça, Ludmila Zanandreis, Melo Júnior, Otoni Alves de Oliveira, Mariano, Reysla Maria da Silveira, Leite, Jaqueline Costa, Silveira, Patricia, Corrêa-Oliveira, Rodrigo, Dutra, Walderez Ornelas, Reis, Alexandre Barbosa, Martins-Filho, Olindo Assis, de Moura, Sandra Aparecida Lima, Silveira-Lemos, Denise, Giunchetti, Rodolfo Cordeiro
Publicado 2020

Corrigendum: Kinetics of Phenotypic and Functional Changes in Mouse Models of Sponge Implants: Rational Selection to Optimize Protocols for Specific Biomolecules Screening Purposes

por Lanna, Mariana Ferreira, Resende, Lucilene Aparecida, Aguiar-Soares, Rodrigo Dian de Oliveira, de Miranda, Marina Barcelos, de Mendonça, Ludmila Zanandreis, Melo Júnior, Otoni Alves de Oliveira, Mariano, Reysla Maria da Silveira, Leite, Jaqueline Costa, Silveira, Patricia, Corrêa-Oliveira, Rodrigo, Dutra, Walderez Ornelas, Reis, Alexandre Barbosa, Martins-Filho, Olindo Assis, de Moura, Sandra Aparecida Lima, Silveira-Lemos, Denise, Giunchetti, Rodolfo Cordeiro
Publicado 2021

In vitro Infectivity of Strains Isolated From Dogs Naturally Infected With Leishmania infantum Present a Distinct Pathogenic Profile in Hamsters

por Resende, Lucilene Aparecida, Aguiar-Soares, Rodrigo Dian de Oliveira, Moreira, Nádia das Dores, Ferreira, Sidney de Almeida, Lanna, Mariana Ferreira, Cardoso, Jamille Mirelle de Oliveira, Mathias, Fernando Augusto Siqueira, Coura-Vital, Wendel, Mariano, Reysla Maria da Silveira, Leite, Jaqueline Costa, Silveira, Patricia, de Carvalho, Tatiane Furtado, Santos, Renato Lima, da Silveira-Lemos, Denise, Martins-Filho, Olindo Assis, Dutra, Walderez Ornelas, Reis, Alexandre Barbosa, Giunchetti, Rodolfo Cordeiro
Publicado 2020