Regulation of CD4(+) T Cell Signaling and Immunological Synapse by Protein Tyrosine Phosphatases: Molecular Mechanisms in Autoimmunity

por Castro-Sánchez, Patricia, Aguilar-Sopeña, Oscar, Alegre-Gómez, Sergio, Ramirez-Munoz, Rocio, Roda-Navarro, Pedro
Publicado 2019

Bispecific Antibody Format and the Organization of Immunological Synapses in T Cell-Redirecting Strategies for Cancer Immunotherapy

por Carrasco-Padilla, Carlos, Hernaiz-Esteban, Alicia, Álvarez-Vallina, Luis, Aguilar-Sopeña, Oscar, Roda-Navarro, Pedro
Publicado 2022

Effect of Pharmacological Inhibition of the Catalytic Activity of Phosphatases of Regenerating Liver in Early T Cell Receptor Signaling Dynamics and IL-2 Production

por Aguilar-Sopeña, Oscar, Hernández-Pérez, Sara, Alegre-Gómez, Sergio, Castro-Sánchez, Patricia, Iglesias-Ceacero, Alba, Lazo, John S., Roda-Navarro, Pedro
Publicado 2020

Fast Diffusion Sustains Plasma Membrane Accumulation of Phosphatase of Regenerating Liver-1

por Castro-Sánchez, Patricia, Hernández-Pérez, Sara, Aguilar-Sopeña, Oscar, Ramírez-Muñoz, Rocia, Rodríguez-Perales, Sandra, Torres-Ruiz, Raúl, Roda-Navarro, Pedro
Publicado 2020

Synapse topology and downmodulation events determine the functional outcome of anti-CD19 T cell-redirecting strategies

por Ramírez-Fernández, Ángel, Aguilar-Sopeña, Óscar, Díez-Alonso, Laura, Segura-Tudela, Alejandro, Domínguez-Alonso, Carmen, Roda-Navarro, Pedro, Álvarez-Vallina, Luis, Blanco, Belén
Publicado 2022

Phosphatase of Regenerating Liver-1 (PRL-1) Regulates Actin Dynamics During Immunological Synapse Assembly and T Cell Effector Function

por Castro-Sánchez, Patricia, Ramirez-Munoz, Rocío, Martín-Cófreces, Noa B., Aguilar-Sopeña, Oscar, Alegre-Gomez, Sergio, Hernández-Pérez, Sara, Reyes, Raquel, Zeng, Qi, Cabañas, Carlos, Sánchez-Madrid, Francisco, Roda-Navarro, Pedro
Publicado 2018

Trispecific T-cell engagers for dual tumor-targeting of colorectal cancer

por Tapia-Galisteo, Antonio, Sánchez Rodríguez, Íñigo, Aguilar-Sopeña, Oscar, Harwood, Seandean Lykke, Narbona, Javier, Ferreras Gutierrez, Mariola, Navarro, Rocío, Martín-García, Laura, Corbacho, Cesáreo, Compte, Marta, Lacadena, Javier, Blanco, Francisco J., Chames, Patrick, Roda-Navarro, Pedro, Álvarez-Vallina, Luis, Sanz, Laura
Publicado 2022

Overcoming CAR-Mediated CD19 Downmodulation and Leukemia Relapse with T Lymphocytes Secreting Anti-CD19 T-cell Engagers

por Blanco, Belén, Ramírez-Fernández, Ángel, Bueno, Clara, Argemí-Muntadas, Lidia, Fuentes, Patricia, Aguilar-Sopeña, Óscar, Gutierrez-Agüera, Francisco, Zanetti, Samanta Romina, Tapia-Galisteo, Antonio, Díez-Alonso, Laura, Segura-Tudela, Alejandro, Castellà, Maria, Marzal, Berta, Betriu, Sergi, Harwood, Seandean L., Compte, Marta, Lykkemark, Simon, Erce-Llamazares, Ainhoa, Rubio-Pérez, Laura, Jiménez-Reinoso, Anaïs, Domínguez-Alonso, Carmen, Neves, Maria, Morales, Pablo, Paz-Artal, Estela, Guedan, Sonia, Sanz, Laura, Toribio, María L., Roda-Navarro, Pedro, Juan, Manel, Menéndez, Pablo, Álvarez-Vallina, Luis
Publicado 2022