The Design and Development of Potent Small Molecules as Anticancer Agents Targeting EGFR TK and Tubulin Polymerization

por Ihmaid, Saleh, Ahmed, Hany E. A., Zayed, Mohamed F.
Publicado 2018

Discovery of novel phthalimide analogs: Synthesis, antimicrobial and antitubercular screening with molecular docking studies

por Rateb, Heba S., Ahmed, Hany E. A., Ahmed, Sahar, Ihmaid, Saleh, Afifi, Tarek H
Publicado 2016

Self Organizing Map-Based Classification of Cathepsin k and S Inhibitors with Different Selectivity Profiles Using Different Structural Molecular Fingerprints: Design and Applicati...

por Ihmaid, Saleh K., Ahmed, Hany E. A., Zayed, Mohamed F., Abadleh, Mohammed M.
Publicado 2016

Design, Synthesis and Cytotoxic Evaluation of Novel Chalcone Derivatives Bearing Triazolo[4,3-a]-quinoxaline Moieties as Potent Anticancer Agents with Dual EGFR Kinase and Tubulin...

por Alswah, Mohamed, Bayoumi, Ashraf H., Elgamal, Kamal, Elmorsy, Ahmed, Ihmaid, Saleh, Ahmed, Hany E. A.
Publicado 2017

Design, Synthesis, Cytotoxic Evaluation and Molecular Docking of New Fluoroquinazolinones as Potent Anticancer Agents with Dual EGFR Kinase and Tubulin Polymerization Inhibitory Ef...

por Zayed, Mohamed F., Ahmed, Sahar, Ihmaid, Saleh, Ahmed, Hany E. A., Rateb, Heba S., Ibrahim, Sabrin R. M.
Publicado 2018

Structure-activity relationships and molecular docking studies of chromene and chromene based azo chromophores: A novel series of potent antimicrobial and anticancer agents

por Afifi, Tarek H., Okasha, Rawda M., Ahmed, Hany E.A., Ilaš, Janez, Saleh, Tarek, Abd-El-Aziz, Alaa S.
Publicado 2017

Synthesis, Modelling, and Anticonvulsant Studies of New Quinazolines Showing Three Highly Active Compounds with Low Toxicity and High Affinity to the GABA-A Receptor

por Zayed, Mohamed F., Ihmaid, Saleh K., Ahmed, Hany E. A., El-Adl, Khaled, Asiri, Ahmed M., Omar, Abdelsattar M.
Publicado 2017

Design, synthesis, molecular modelling and in vitro screening of monoamine oxidase inhibitory activities of novel quinazolyl hydrazine derivatives

por Amer, Adel, Hegazi, Abdelrahman H., Alshekh, Mohammed Khalil, Ahmed, Hany E. A., Soliman, Saied M., Maniquet, Antonin, Ramsay, Rona R.
Publicado 2020

Berberine Reduces Neurotoxicity Related to Nonalcoholic Steatohepatitis in Rats

por Ghareeb, Doaa A., Khalil, Sofia, Hafez, Hani S., Bajorath, Jürgen, Ahmed, Hany E. A., Sarhan, Eman, Elwakeel, Eiman, El-Demellawy, Maha A.
Publicado 2015

Exploring structure-activity relationship of S-substituted 2-mercaptoquinazolin-4(3H)-one including 4-ethylbenzenesulfonamides as human carbonic anhydrase inhibitors

por El-Azab, Adel S., Abdel-Aziz, Alaa A.-M., Ahmed, Hany E. A., Bua, Sivia, Nocentini, Alessio, AlSaif, Nawaf A., Obaidullah, Ahmad J., Hefnawy, Mohamed M., Supuran, Claudiu T.
Publicado 2020

Introducing novel potent anticancer agents of 1H-benzo[f]chromene scaffolds, targeting c-Src kinase enzyme with MDA-MB-231 cell line anti-invasion effect

por Ahmed, Hany E. A., El-Nassag, Mohammed A. A., Hassan, Ahmed H., Okasha, Rawda M., Ihmaid, Saleh, Fouda, Ahmed M., Afifi, Tarek H., Aljuhani, Ateyatallah, El-Agrody, Ahmed M.
Publicado 2018

S-substituted 2-mercaptoquinazolin-4(3H)-one and 4-ethylbenzensulfonamides act as potent and selective human carbonic anhydrase IX and XII inhibitors

por El-Azab, Adel S., Abdel-Aziz, Alaa A.-M., Bua, Silvia, Nocentini, Alessio, AlSaif, Nawaf A., Alanazi, Mohammed M., El-Gendy, Manal A., Ahmed, Hany E. A., Supuran, Claudiu T.
Publicado 2020

Design and Synthesis of Benzene Homologues Tethered with 1,2,4-Triazole and 1,3,4-Thiadiazole Motifs Revealing Dual MCF-7/HepG2 Cytotoxic Activity with Prominent Selectivity via Hi...

por Alsehli, Mosa, Aljuhani, Ateyatallah, Ihmaid, Saleh K., El-Messery, Shahenda M., Othman, Dina I. A., El-Sayed, Abdel-Aziz A. A., Ahmed, Hany E. A., Rezki, Nadjet, Aouad, Mohamed R.
Publicado 2022

Development of Novel Class of Phenylpyrazolo[3,4-d]pyrimidine-Based Analogs with Potent Anticancer Activity and Multitarget Enzyme Inhibition Supported by Docking Studies

por Aljohani, Ahmed K. B., El Zaloa, Waheed Ali Zaki, Alswah, Mohamed, Seleem, Mohamed A., Elsebaei, Mohamed M., Bayoumi, Ashraf H., El-Morsy, Ahmed M., Almaghrabi, Mohammed, Awaji, Aeshah A., Hammad, Ali, Alsulaimany, Marwa, Ahmed, Hany E. A.
Publicado 2023

In vitro and computational investigations of novel synthetic carboxamide-linked pyridopyrrolopyrimidines with potent activity as SARS-CoV-2-M(Pro) inhibitors

por Aljuhani, Ateyatallah, Ahmed, Hany E. A., Ihmaid, Saleh K., Omar, Abdelsattar M., Althagfan, Sultan S., Alahmadi, Yaser M., Ahmad, Iqrar, Patel, Harun, Ahmed, Sahar, Almikhlafi, Mohannad A., El-Agrody, Ahmed M., Zayed, Mohamed F., Turkistani, Safaa Abdulrahman, Abulkhair, Shorouk H., Almaghrabi, Mohammed, Salama, Samir A., Al-Karmalawy, Ahmed A., Abulkhair, Hamada S.
Publicado 2022