Intrinsic DNA topology as a prioritization metric in genomic fine-mapping studies

por Ainsworth, Hannah C, Howard, Timothy D, Langefeld, Carl D
Publicado 2020

Adaptive Evolution of the FADS Gene Cluster within Africa

por Mathias, Rasika A., Fu, Wenqing, Akey, Joshua M., Ainsworth, Hannah C., Torgerson, Dara G., Ruczinski, Ingo, Sergeant, Susan, Barnes, Kathleen C., Chilton, Floyd H.
Publicado 2012

Gut dysbiosis and the clinical spectrum in anti-Ro positive mothers of children with neonatal lupus

por Clancy, Robert M., Marion, Miranda C., Ainsworth, Hannah C., Chang, Miao, Howard, Timothy D., Izmirly, Peter M., Masson, Mala, Buyon, Jill P., Langefeld, Carl D.
Publicado 2022

LTC(4) synthase polymorphism modifies efficacy of botanical seed oil combination in asthma

por Kazani, Shamsah, Arm, Jonathan P, Boyce, Joshua, Chhay, Heng, Dutile, Stefanie, Wechsler, Michael E, Govindarajulu, Usha, Ivester, Priscilla, Ainsworth, Hannah C, Sergeant, Susan, Chilton, Floyd H, Israel, Elliot
Publicado 2014

Allele-specific methylation in the FADS genomic region in DNA from human saliva, CD4+ cells, and total leukocytes

por Rahbar, Elaheh, Waits, Charlotte Mae K., Kirby, Edward H., Miller, Leslie R., Ainsworth, Hannah C., Cui, Tao, Sergeant, Susan, Howard, Timothy D., Langefeld, Carl D., Chilton, Floyd H.
Publicado 2018

Uncovering the DNA methylation landscape in key regulatory regions within the FADS cluster

por Rahbar, Elaheh, Ainsworth, Hannah C., Howard, Timothy D., Hawkins, Gregory A., Ruczinski, Ingo, Mathias, Rasika, Seeds, Michael C., Sergeant, Susan, Hixson, James E., Herrington, David M., Langefeld, Carl D., Chilton, Floyd H.
Publicado 2017

Comparison of different gene addition strategies to modify placental derived-mesenchymal stromal cells to produce FVIII

por Ramamurthy, Ritu M., Rodriguez, Martin, Ainsworth, Hannah C., Shields, Jordan, Meares, Diane, Bishop, Colin, Farland, Andrew, Langefeld, Carl D., Atala, Anthony, Doering, Christopher B., Spencer, H. Trent, Porada, Christopher D., Almeida-Porada, Graça
Publicado 2022

DNA Methylation in an Enhancer Region of the FADS Cluster Is Associated with FADS Activity in Human Liver

por Howard, Timothy D., Mathias, Rasika A., Seeds, Michael C., Herrington, David M., Hixson, James E., Shimmin, Lawrence C., Hawkins, Greg A., Sellers, Matthew, Ainsworth, Hannah C., Sergeant, Susan, Miller, Leslie R., Chilton, Floyd H.
Publicado 2014

Single-cell expression quantitative trait loci (eQTL) analysis of SLE-risk loci in lupus patient monocytes

por Ghodke-Puranik, Yogita, Jin, Zhongbo, Zimmerman, Kip D., Ainsworth, Hannah C., Fan, Wei, Jensen, Mark A., Dorschner, Jessica M., Vsetecka, Danielle M., Amin, Shreyasee, Makol, Ashima, Ernste, Floranne, Osborn, Thomas, Moder, Kevin, Chowdhary, Vaidehi, Langefeld, Carl D., Niewold, Timothy B.
Publicado 2021

Nucleic Acid-Sensing and Interferon-Inducible Pathways Show Differential Methylation in MZ Twins Discordant for Lupus and Overexpression in Independent Lupus Samples: Implications...

por Marion, Miranda C., Ramos, Paula S., Bachali, Prathyusha, Labonte, Adam C., Zimmerman, Kip D., Ainsworth, Hannah C., Heuer, Sarah E., Robl, Robert D., Catalina, Michelle D., Kelly, Jennifer A., Howard, Timothy D., Lipsky, Peter E., Grammer, Amrie C., Langefeld, Carl D.
Publicado 2021

Metabolomic architecture of obesity implicates metabolonic lactone sulfate in cardiometabolic disease

por Das, Swapan K., Ainsworth, Hannah C., Dimitrov, Latchezar, Okut, Hayrettin, Comeau, Mary E., Sharma, Neeraj, Ng, Maggie C.Y., Norris, Jill M., Chen, Yii-der I., Wagenknecht, Lynne E., Bowden, Donald W., Hsu, Fang-Chi, Taylor, Kent D., Langefeld, Carl D., Palmer, Nicholette D.
Publicado 2021

APOL1 Kidney-Risk Variants Induce Mitochondrial Fission

por Ma, Lijun, Ainsworth, Hannah C., Snipes, James A., Murea, Mariana, Choi, Young A, Langefeld, Carl D., Parks, John S., Bharadwaj, Manish S., Chou, Jeff W., Hemal, Ashok K., Petrovic, Snezana, Craddock, Ann L., Cheng, Dongmei, Hawkins, Gregory A., Miller, Lance D., Hicks, Pamela J., Saleem, Moin A., Divers, Jasmin, Molina, Anthony J.A., Freedman, Barry I.
Publicado 2020

Brief Report: The Genetic Profile of Rheumatoid Factor–Positive Polyarticular Juvenile Idiopathic Arthritis Resembles That of Adult Rheumatoid Arthritis

por Hinks, Anne, Marion, Miranda C., Cobb, Joanna, Comeau, Mary E., Sudman, Marc, Ainsworth, Hannah C., Bowes, John, Becker, Mara L., Bohnsack, John F., Haas, Johannes‐Peter, Lovell, Daniel J., Mellins, Elizabeth D., Nelson, J. Lee, Nordal, Ellen, Punaro, Marilynn, Reed, Ann M., Rose, Carlos D., Rosenberg, Alan M., Rygg, Marite, Smith, Samantha L., Stevens, Anne M., Videm, Vibeke, Wallace, Carol A., Wedderburn, Lucy R., Yarwood, Annie, Yeung, Rae S. M., Langefeld, Carl D., Thompson, Susan D., Thomson, Wendy, Prahalad, Sampath
Publicado 2018

Genetic and Clinical Predictors of Age of ESKD in Individuals With Autosomal Dominant Tubulointerstitial Kidney Disease Due to UMOD Mutations

por Kidd, Kendrah, Vylet’al, Petr, Schaeffer, Céline, Olinger, Eric, Živná, Martina, Hodaňová, Kateřina, Robins, Victoria, Johnson, Emily, Taylor, Abbigail, Martin, Lauren, Izzi, Claudia, Jorge, Sofia C., Calado, Joaquim, Torres, Rosa J., Lhotta, Karl, Steubl, Dominik, Gale, Daniel P., Gast, Christine, Gombos, Eva, Ainsworth, Hannah C., Chen, Ying Maggie, Almeida, Jorge Reis, de Souza, Cintia Fernandes, Silveira, Catarina, Raposeiro, Rita, Weller, Nelson, Conlon, Peter J., Murray, Susan L., Benson, Katherine A., Cavalleri, Gianpiero L., Votruba, Miroslav, Vrbacká, Alena, Amoroso, Antonio, Gianchino, Daniela, Caridi, Gianluca, Ghiggeri, Gian Marco, Divers, Jasmin, Scolari, Francesco, Devuyst, Olivier, Rampoldi, Luca, Kmoch, Stanislav, Bleyer, Anthony J.
Publicado 2020

Genome-wide imputation study identifies novel HLA locus for pulmonary fibrosis and potential role for auto-immunity in fibrotic idiopathic interstitial pneumonia

por Fingerlin, Tasha E., Zhang, Weiming, Yang, Ivana V., Ainsworth, Hannah C., Russell, Pamela H., Blumhagen, Rachel Z., Schwarz, Marvin I., Brown, Kevin K., Steele, Mark P., Loyd, James E., Cosgrove, Gregory P., Lynch, David A., Groshong, Steve, Collard, Harold R., Wolters, Paul J., Bradford, Williamson Z., Kossen, Karl, Seiwert, Scott D., du Bois, Roland M., Garcia, Christine Kim, Devine, Megan S., Gudmundsson, Gunnar, Isaksson, Helgi J., Kaminski, Naftali, Zhang, Yingze, Gibson, Kevin F., Lancaster, Lisa H., Maher, Toby M., Molyneaux, Philip L., Wells, Athol U., Moffatt, Miriam F., Selman, Moises, Pardo, Annie, Kim, Dong Soon, Crapo, James D., Make, Barry J., Regan, Elizabeth A., Walek, Dinesha S., Daniel, Jerry J., Kamatani, Yoichiro, Zelenika, Diana, Murphy, Elissa, Smith, Keith, McKean, David, Pedersen, Brent S., Talbert, Janet, Powers, Julia, Markin, Cheryl R., Beckman, Kenneth B., Lathrop, Mark, Freed, Brian, Langefeld, Carl D., Schwartz, David A.
Publicado 2016

Transancestral mapping and genetic load in systemic lupus erythematosus

por Langefeld, Carl D., Ainsworth, Hannah C., Graham, Deborah S. Cunninghame, Kelly, Jennifer A., Comeau, Mary E., Marion, Miranda C., Howard, Timothy D., Ramos, Paula S., Croker, Jennifer A., Morris, David L., Sandling, Johanna K., Almlöf, Jonas Carlsson, Acevedo-Vásquez, Eduardo M., Alarcón, Graciela S., Babini, Alejandra M., Baca, Vicente, Bengtsson, Anders A., Berbotto, Guillermo A., Bijl, Marc, Brown, Elizabeth E., Brunner, Hermine I., Cardiel, Mario H., Catoggio, Luis, Cervera, Ricard, Cucho-Venegas, Jorge M., Dahlqvist, Solbritt Rantapää, D’Alfonso, Sandra, Da Silva, Berta Martins, de la Rúa Figueroa, Iñigo, Doria, Andrea, Edberg, Jeffrey C., Endreffy, Emőke, Esquivel-Valerio, Jorge A., Fortin, Paul R., Freedman, Barry I., Frostegård, Johan, García, Mercedes A., de la Torre, Ignacio García, Gilkeson, Gary S., Gladman, Dafna D., Gunnarsson, Iva, Guthridge, Joel M., Huggins, Jennifer L., James, Judith A., Kallenberg, Cees G. M., Kamen, Diane L., Karp, David R., Kaufman, Kenneth M., Kottyan, Leah C., Kovács, László, Laustrup, Helle, Lauwerys, Bernard R., Li, Quan-Zhen, Maradiaga-Ceceña, Marco A., Martín, Javier, McCune, Joseph M., McWilliams, David R., Merrill, Joan T., Miranda, Pedro, Moctezuma, José F., Nath, Swapan K., Niewold, Timothy B., Orozco, Lorena, Ortego-Centeno, Norberto, Petri, Michelle, Pineau, Christian A., Pons-Estel, Bernardo A., Pope, Janet, Raj, Prithvi, Ramsey-Goldman, Rosalind, Reveille, John D., Russell, Laurie P., Sabio, José M., Aguilar-Salinas, Carlos A., Scherbarth, Hugo R., Scorza, Raffaella, Seldin, Michael F., Sjöwall, Christopher, Svenungsson, Elisabet, Thompson, Susan D., Toloza, Sergio M. A., Truedsson, Lennart, Tusié-Luna, Teresa, Vasconcelos, Carlos, Vilá, Luis M., Wallace, Daniel J., Weisman, Michael H., Wither, Joan E., Bhangale, Tushar, Oksenberg, Jorge R., Rioux, John D., Gregersen, Peter K., Syvänen, Ann-Christine, Rönnblom, Lars, Criswell, Lindsey A., Jacob, Chaim O., Sivils, Kathy L., Tsao, Betty P., Schanberg, Laura E., Behrens, Timothy W., Silverman, Earl D., Alarcón-Riquelme, Marta E., Kimberly, Robert P., Harley, John B., Wakeland, Edward K., Graham, Robert R., Gaffney, Patrick M., Vyse, Timothy J.
Publicado 2017