Metabolism of a Bioorthogonal PET Tracer Candidate [(19)F/(18)F]SiFA-Tetrazine in Mouse Liver Microsomes: Biotransformation Pathways and Defluorination Investigated by UHPLC-HRMS

por Otaru, Sofia, Niemikoski, Hanna, Sarparanta, Mirkka, Airaksinen, Anu J.
Publicado 2020

Evaluation of Organo [(18)F]Fluorosilicon Tetrazine as a Prosthetic Group for the Synthesis of PET Radiotracers

por Otaru, Sofia, Imlimthan, Surachet, Sarparanta, Mirkka, Helariutta, Kerttuli, Wähälä, Kristiina, Airaksinen, Anu J.
Publicado 2020

Radiolabelling of peptides with tetrazine ligation based on the inverse electron-demand Diels–Alder reaction: rapid, catalyst-free and mild conversion of 1,4-dihydropyridazines to...

por Otaru, Sofia, Martinmäki, Tatu, Kuurne, Iida, Paulus, Andreas, Helariutta, Kerttuli, Sarparanta, Mirkka, Airaksinen, Anu J.
Publicado 2023

Site-Specific (111)In-Radiolabeling of Dual-PEGylated Porous Silicon Nanoparticles and Their In Vivo Evaluation in Murine 4T1 Breast Cancer Model

por Lumen, Dave, Näkki, Simo, Imlimthan, Surachet, Lambidis, Elisavet, Sarparanta, Mirkka, Xu, Wujun, Lehto, Vesa-Pekka, Airaksinen, Anu J.
Publicado 2019

Development of (68)Ga-Labeled Hepatitis E Virus Nanoparticles for Targeted Drug Delivery and Diagnostics with PET

por Lambidis, Elisavet, Chen, Chun-Chieh, Baikoghli, Mo, Imlimthan, Surachet, Khng, You Cheng, Sarparanta, Mirkka, Cheng, R. Holland, Airaksinen, Anu J.
Publicado 2022

SPECT/CT Imaging of hNIS -Expression after Intravenous Delivery of an Oncolytic Adenovirus and (131)I

por Rajecki, Maria, Sarparanta, Mirkka, Hakkarainen, Tanja, Tenhunen, Mikko, Diaconu, Iulia, Kuhmonen, Venla, Kairemo, Kalevi, Kanerva, Anna, Airaksinen, Anu J., Hemminki, Akseli
Publicado 2012

Oncolytic adenovirus improves anti-tumor efficacy of adoptive T cell therapy by breaking tumor-induced immunosuppression and peripheral tolerance

por Tähtinen, Siri, Grönberg-Vähä-Koskela, Susanna, Lumen, Dave, Merisalo-Soikkeli, Maiju, Siurala, Mikko, Airaksinen, Anu J, Vähä-Koskela, Markus, Hemminki, Akseli
Publicado 2015

Porous Silicon as a Platform for Radiation Theranostics Together with a Novel RIB-Based Radiolanthanoid

por Jakobsson, Ulrika, Mäkilä, Ermei, Airaksinen, Anu J, Alanen, Osku, Etilé, Asenath, Köster, Ulli, Ranjan, Sanjeev, Salonen, Jarno, Santos, Hélder A, Helariutta, Kerttuli
Publicado 2019

Porous Silicon as a Platform for Radiation Theranostics Together with a Novel RIB-Based Radiolanthanoid

por Jakobsson, Ulrika, Mäkilä, Ermei, Airaksinen, Anu J., Alanen, Osku, Etilé, Asenath, Köster, Ulli, Ranjan, Sanjeev, Salonen, Jarno, Santos, Hélder A., Helariutta, Kerttuli
Publicado 2019

Pretargeting of internalizing trastuzumab and cetuximab with a (18)F-tetrazine tracer in xenograft models

por Keinänen, Outi, Fung, Kimberly, Pourat, Jacob, Jallinoja, Vilma, Vivier, Delphine, Pillarsetty, NagaVara Kishore, Airaksinen, Anu J., Lewis, Jason S., Zeglis, Brian M., Sarparanta, Mirkka
Publicado 2017

In Vivo Imaging of [60]Fullerene-Based Molecular Spherical Nucleic Acids by Positron Emission Tomography

por Äärelä, Antti, Auchynnikava, Tatsiana, Moisio, Olli, Liljenbäck, Heidi, Andriana, Putri, Iqbal, Imran, Lehtimäki, Jyrki, Rajander, Johan, Salo, Harri, Roivainen, Anne, Airaksinen, Anu J., Virta, Pasi
Publicado 2023

Abscopal Effect in Non-injected Tumors Achieved with Cytokine-Armed Oncolytic Adenovirus

por Havunen, Riikka, Santos, João M., Sorsa, Suvi, Rantapero, Tommi, Lumen, Dave, Siurala, Mikko, Airaksinen, Anu J., Cervera-Carrascon, Victor, Tähtinen, Siri, Kanerva, Anna, Hemminki, Akseli
Publicado 2018

Development of [(18)F]AmBF(3) Tetrazine for Radiolabeling of Peptides: Preclinical Evaluation and PET Imaging of [(18)F]AmBF(3)-PEG(7)-Tyr(3)-Octreotide in an AR42J Pancreatic Carc...

por Otaru, Sofia, Paulus, Andreas, Imlimthan, Surachet, Kuurne, Iida, Virtanen, Helena, Liljenbäck, Heidi, Tolvanen, Tuula, Auchynnikava, Tatsiana, Roivainen, Anne, Helariutta, Kerttuli, Sarparanta, Mirkka, Airaksinen, Anu J.
Publicado 2022

Localized delivery of compounds into articular cartilage by using high-intensity focused ultrasound

por Nieminen, Heikki J., Lampsijärvi, Eetu, Barreto, Gonçalo, Finnilä, Mikko A. J., Salmi, Ari, Airaksinen, Anu J., Eklund, Kari K., Saarakkala, Simo, Pritzker, Kenneth P. H., Hæggström, Edward
Publicado 2019

Pretargeted PET Imaging of trans-Cyclooctene-Modified Porous Silicon Nanoparticles

por Keinänen, Outi, Mäkilä, Ermei M., Lindgren, Rici, Virtanen, Helena, Liljenbäck, Heidi, Oikonen, Vesa, Sarparanta, Mirkka, Molthoff, Carla, Windhorst, Albert D., Roivainen, Anne, Salonen, Jarno J., Airaksinen, Anu J.
Publicado 2017

Improved synthesis of [(18)F] fallypride and characterization of a Huntington’s disease mouse model, zQ175DN KI, using longitudinal PET imaging of D2/D3 receptors

por Huhtala, Tuulia, Poutiainen, Pekka, Rytkönen, Jussi, Lehtimäki, Kimmo, Parkkari, Teija, Kasanen, Iiris, Airaksinen, Anu J., Koivula, Teija, Sweeney, Patrick, Kontkanen, Outi, Wityak, John, Dominiquez, Celia, Park, Larry C.
Publicado 2019

Pretargeted PET Imaging with a TCO-Conjugated Anti-CD44v6 Chimeric mAb U36 and [(89)Zr]Zr-DFO-PEG(5)-Tz

por Lumen, Dave, Vugts, Danielle, Chomet, Marion, Imlimthan, Surachet, Sarparanta, Mirkka, Vos, Ricardo, Schreurs, Maxime, Verlaan, Mariska, Lang, Pauline A., Hippeläinen, Eero, Beaino, Wissam, Windhorst, Albert D., Airaksinen, Anu J.
Publicado 2022

Preparation and in vivo evaluation of red blood cell membrane coated porous silicon nanoparticles implanted with $^{155}$Tb

por Jakobsson, Ulrika, Mäkilä, Ermei, Rahikkala, Antti, Imlimthan, Surachet, Lampuoti, Jarkko, Ranjan, Sanjeev, Heino, Jouni, Jalkanen, Pasi, Köster, Ulli, Mizohata, Kenichiro, Santos, Hélder A., Salonen, Jarno, Airaksinen, Anu J., Sarparanta, Mirkka, Helariutta, Kerttuli
Publicado 2020

First Evaluation of [(11)C]R116301 as an In Vivo Tracer of NK1 Receptors in Man

por Wolfensberger, Saskia P. A., van Berckel, Bart N. M., Airaksinen, Anu J., Maruyama, Kaoru, Lubberink, Mark, Boellaard, Ronald, Carey, William D. H., Reddingius, Wieb, Veltman, Dick J., Windhorst, Albert D., Leysen, Josée E., Lammertsma, Adriaan A.
Publicado 2009

Addressing the Biochemical Foundations of a Glucose-Based “Trojan Horse”-Strategy to Boron Neutron Capture Therapy: From Chemical Synthesis to In Vitro Assessment

por Matović, Jelena, Järvinen, Juulia, Bland, Helena C., Sokka, Iris K., Imlimthan, Surachet, Ferrando, Ruth Mateu, Huttunen, Kristiina M., Timonen, Juri, Peräniemi, Sirpa, Aitio, Olli, Airaksinen, Anu J., Sarparanta, Mirkka, Johansson, Mikael P., Rautio, Jarkko, Ekholm, Filip S.
Publicado 2020