ATM in senescence

por Aird, Katherine M., Zhang, Rugang
Publicado 2015

Metabolic alterations accompanying oncogene-induced senescence

por Aird, Katherine M, Zhang, Rugang
Publicado 2014

Ataxia-Telangiectasia Mutated Modulation of Carbon Metabolism in Cancer

por Dahl, Erika S., Aird, Katherine M.
Publicado 2017

Deoxyribonucleotide Triphosphate Metabolism in Cancer and Metabolic Disease

por Buj, Raquel, Aird, Katherine M.
Publicado 2018

p16: cycling off the beaten path

por Buj, Raquel, Aird, Katherine M.
Publicado 2019

Jumonji C Demethylases in Cellular Senescence

por Leon, Kelly E., Aird, Katherine M.
Publicado 2019

53BP1: guarding the genome with a novel liquid weapon

por Tangudu, Naveen Kumar, Aird, Katherine M.
Publicado 2022

Chromatin remodeling, BRCA1, SAHF and cellular senescence

por Tu, Zhigang, Aird, Katherine M., Zhang, Rugang
Publicado 2013

Suppression of p16 alleviates the senescence-associated secretory phenotype

por Buj, Raquel, Leon, Kelly E., Anguelov, Marlyn A., Aird, Katherine M.
Publicado 2021

Loss of p16: A Bouncer of the Immunological Surveillance?

por Leon, Kelly E., Tangudu, Naveen Kumar, Aird, Katherine M., Buj, Raquel
Publicado 2021

ATM inhibition synergizes with fenofibrate in high grade serous ovarian cancer cells

por Chen, Chi-Wei, Buj, Raquel, Dahl, Erika S., Leon, Kelly E., Aird, Katherine M.
Publicado 2020

Overexpression of oncogenic H-Ras in hTERT-immortalized and SV40-transformed human cells targets replicative and specialized DNA polymerases for depletion

por Tsao, Wei-chung, Buj, Raquel, Aird, Katherine M., Sidorova, Julia M., Eckert, Kristin A.
Publicado 2021

Topoisomerase 1 cleavage complex enables pattern recognition and inflammation during senescence

por Zhao, Bo, Liu, Pingyu, Fukumoto, Takeshi, Nacarelli, Timothy, Fatkhutdinov, Nail, Wu, Shuai, Lin, Jianhuang, Aird, Katherine M., Tang, Hsin-Yao, Liu, Qin, Speicher, David W., Zhang, Rugang
Publicado 2020

DOT1L modulates the senescence-associated secretory phenotype through epigenetic regulation of IL1A

por Leon, Kelly E., Buj, Raquel, Lesko, Elizabeth, Dahl, Erika S., Chen, Chi-Wei, Tangudu, Naveen Kumar, Imamura-Kawasawa, Yuka, Kossenkov, Andrew V., Hobbs, Ryan P., Aird, Katherine M.
Publicado 2021

HMGB2 orchestrates the chromatin landscape of senescence-associated secretory phenotype gene loci

por Aird, Katherine M., Iwasaki, Osamu, Kossenkov, Andrew V., Tanizawa, Hideki, Fatkhutdinov, Nail, Bitler, Benjamin G., Le, Linh, Alicea, Gretchen, Yang, Ting-Lin, Johnson, F. Brad, Noma, Ken-ichi, Zhang, Rugang
Publicado 2016

CLIC1 and CLIC4 complement CA125 as a diagnostic biomarker panel for all subtypes of epithelial ovarian cancer

por Singha, Bipradeb, Harper, Sandra L., Goldman, Aaron R., Bitler, Benjamin G., Aird, Katherine M., Borowsky, Mark E., Cadungog, Mark G., Liu, Qin, Zhang, Rugang, Jean, Stephanie, Drapkin, Ronny, Speicher, David W.
Publicado 2018

Targeting EZH2 methyltransferase activity in ARID1A mutated cancer cells is synthetic lethal

por Biter, Benjamin G., Aird, Katherine M., Garipov, Azat, Li, Hua, Amatangelo, Michael, Kossenkov, Andrew V., Schultz, David C., Liu, Qin, Shih, Ie-Ming, Conejo-Garcia, Jose R., Speicher, David W., Zhang, Rugang
Publicado 2015

ATM inhibition drives metabolic adaptation via induction of macropinocytosis

por Huang, Zhentai, Chen, Chi-Wei, Buj, Raquel, Tangudu, Naveen Kumar, Fang, Richard S., Leon, Kelly E., Dahl, Erika S., Varner, Erika L., von Krusenstiern, Eliana, Cole, Aidan R., Snyder, Nathaniel W., Aird, Katherine M.
Publicado 2022

ATR promotes mTORC1 activation via de novo cholesterol synthesis in p16-low cancer cells

por Tangudu, Naveen Kumar, Huang, Zhentai, Fang, Richard, Buj, Raquel, Uboveja, Apoorva, Cole, Aidan R., Happe, Cassandra, Sun, Mai, Gelhaus, Stacy L., MacDonald, Matthew L., Hempel, Nadine, Snyder, Nathaniel W., Aird, Katherine M.
Publicado 2023

De novo purine metabolism is a metabolic vulnerability of cancers with low p16 expression

por Tangudu, Naveen Kumar, Buj, Raquel, Wang, Hui, Wang, Jiefei, Cole, Aidan R., Uboveja, Apoorva, Fang, Richard, Amalric, Amandine, Sajjakulnukit, Peter, Lyons, Maureen A., Cooper, Kristine, Hempel, Nadine, Snyder, Nathaniel W., Lyssiotis, Costas A., Chandran, Uma R., Aird, Katherine M.
Publicado 2023