A Novel Ruthenium(II) Complex With Lapachol Induces G2/M Phase Arrest Through Aurora-B Kinase Down-Regulation and ROS-Mediated Apoptosis in Human Prostate Adenocarcinoma Cells

por De Grandis, Rone A., Oliveira, Katia M., Guedes, Adriana P. M., dos Santos, Patrick W. S., Aissa, Alexandre F., Batista, Alzir A., Pavan, Fernando R.
Publicado 2021

CR-LAAO, an L-amino acid oxidase from Calloselasma rhodostoma venom, as a potential tool for developing novel immunotherapeutic strategies against cancer

por Costa, Tássia R., Menaldo, Danilo L., Zoccal, Karina F., Burin, Sandra M., Aissa, Alexandre F., Castro, Fabíola A. de, Faccioli, Lúcia H., Greggi Antunes, Lusânia M., Sampaio, Suely V.
Publicado 2017

A non-catalytic scaffolding activity of hexokinase 2 contributes to EMT and metastasis

por Blaha, Catherine S., Ramakrishnan, Gopalakrishnan, Jeon, Sang-Min, Nogueira, Veronique, Rho, Hyunsoo, Kang, Soeun, Bhaskar, Prashanth, Terry, Alexander R., Aissa, Alexandre F., Frolov, Maxim V., Patra, Krushna C., Brooks Robey, R., Hay, Nissim
Publicado 2022

Calcium channel blockers potentiate gemcitabine chemotherapy  in pancreatic cancer

por Principe, Daniel R., Aissa, Alexandre F., Kumar, Sandeep, Pham, Thao N. D., Underwood, Patrick W., Nair, Rakesh, Ke, Rong, Rana, Basabi, Trevino, Jose G., Munshi, Hidayatullah G., Benevolenskaya, Elizaveta V., Rana, Ajay
Publicado 2022

Single-cell transcriptional changes associated with drug tolerance and response to combination therapies in cancer

por Aissa, Alexandre F., Islam, Abul B. M. M. K., Ariss, Majd M., Go, Cammille C., Rader, Alexandra E., Conrardy, Ryan D., Gajda, Alexa M., Rubio-Perez, Carlota, Valyi-Nagy, Klara, Pasquinelli, Mary, Feldman, Lawrence E., Green, Stefan J., Lopez-Bigas, Nuria, Frolov, Maxim V., Benevolenskaya, Elizaveta V.
Publicado 2021