A retrospective examination of the US Food and Drug Administration’s clinical pharmacology reviews of oncology biologics for potential use of therapeutic drug monitoring

por Fleisher, Brett, Ait-Oudhia, Sihem
Publicado 2017

Current advances in biomarkers for targeted therapy in triple-negative breast cancer

por Fleisher, Brett, Clarke, Charlotte, Ait-Oudhia, Sihem
Publicado 2016

Mechanisms, monitoring, and management of tyrosine kinase inhibitors–associated cardiovascular toxicities

por Chaar, Maher, Kamta, Jeff, Ait-Oudhia, Sihem
Publicado 2018

In vitro to clinical translational pharmacokinetic/pharmacodynamic modeling of doxorubicin (DOX) and dexrazoxane (DEX) interactions: Safety assessment and optimization

por Mody, Hardik, Vaidya, Tanaya R., Ait-Oudhia, Sihem
Publicado 2023

Application of Pharmacokinetic and Pharmacodynamic Analysis to the Development of Liposomal Formulations for Oncology

por Ait-Oudhia, Sihem, Mager, Donald E., Straubinger, Robert M.
Publicado 2014

Understanding the role of PD-L1/PD1 pathway blockade and autophagy in cancer therapy

por Robainas, Marianela, Otano, Rafael, Bueno, Stephen, Ait-Oudhia, Sihem
Publicado 2017

Anticancer and cardio-protective effects of liposomal doxorubicin in the treatment of breast cancer

por Franco, Yesenia L, Vaidya, Tanaya R, Ait-Oudhia, Sihem
Publicado 2018

Chloroquine sensitizes MDA-MB-231 cells to osimertinib through autophagy–apoptosis crosstalk pathway

por Fleisher, Brett, Mody, Hardik, Werkman, Carolin, Ait-Oudhia, Sihem
Publicado 2019

In vitro to Clinical Translation of Combinatorial Effects of Doxorubicin and Abemaciclib in Rb-Positive Triple Negative Breast Cancer: A Systems-Based Pharmacokinetic/Pharmacodynam...

por Fleisher, Brett, Lezeau, Jovin, Werkman, Carolin, Jacobs, Brehanna, Ait-Oudhia, Sihem
Publicado 2021

Pharmacodynamic Modeling to Evaluate the Impact of Cimetidine, an OCT2 Inhibitor, on the Anticancer Effects of Cisplatin

por Mody, Hardik, Vaidya, Tanaya R., Lesko, Lawrence J., Ait-Oudhia, Sihem
Publicado 2022

In vitro to clinical translation of combinatorial effects of doxorubicin and dexrazoxane in breast cancer: a mechanism-based pharmacokinetic/pharmacodynamic modeling approach

por Mody, Hardik, Vaidya, Tanaya R., Lezeau, Jovin, Taha, Kareem, Ait-Oudhia, Sihem
Publicado 2023

Advancing Cancer Therapy with Present and Emerging Immuno-Oncology Approaches

por Kamta, Jeff, Chaar, Maher, Ande, Anusha, Altomare, Deborah A., Ait-Oudhia, Sihem
Publicado 2017

Pharmacodynamic Modeling of Cell Cycle Effects for Gemcitabine and Trabectedin Combinations in Pancreatic Cancer Cells

por Miao, Xin, Koch, Gilbert, Ait-Oudhia, Sihem, Straubinger, Robert M., Jusko, William J.
Publicado 2016

Utility of a Novel Three-Dimensional and Dynamic (3DD) Cell Culture System for PK/PD Studies: Evaluation of a Triple Combination Therapy at Overcoming Anti-HER2 Treatment Resistanc...

por Ande, Anusha, Vaidya, Tanaya R., Tran, Bao N., Vicchiarelli, Michael, Brown, Ashley N., Ait-Oudhia, Sihem
Publicado 2018

Population pharmacokinetic analysis of the P2X3‐receptor antagonist gefapixant

por Chawla, Akshita, Largajolli, Anna, Hussain, Azher, Kleijn, Huub, Ait‐Oudhia, Sihem, Anton, Judith, Krishna Ananthula, Hari, Nussbaum, Jesse, La Rosa, Carmen, Gheyas, Ferdous
Publicado 2023