Genomic structure of nucleotide diversity among Lyon rat models of metabolic syndrome

por Ma, Man Chun John, Atanur, Santosh S, Aitman, Timothy J, Kwitek, Anne E
Publicado 2014

JunD/AP1 regulatory network analysis during macrophage activation in a rat model of crescentic glomerulonephritis

por Srivastava, Prashant K, Hull, Richard P, Behmoaras, Jacques, Petretto, Enrico, Aitman, Timothy J
Publicado 2013

Performance evaluation of Sanger sequencing for the diagnosis of primary hyperoxaluria and comparison with targeted next generation sequencing

por Williams, Emma L, Bagg, Eleanor A L, Mueller, Michael, Vandrovcova, Jana, Aitman, Timothy J, Rumsby, Gill
Publicado 2015

Inherited Thoracic Aortic Disease: New Insights and Translational Targets

por Fletcher, Alexander J., Syed, Maaz B.J., Aitman, Timothy J., Newby, David E., Walker, Niki L.
Publicado 2020

Integrated genomic approaches to identification of candidate genes underlying metabolic and cardiovascular phenotypes in the spontaneously hypertensive rat

por Morrissey, Catherine, Grieve, Ian C., Heinig, Matthias, Atanur, Santosh, Petretto, Enrico, Pravenec, Michal, Hubner, Norbert, Aitman, Timothy J.
Publicado 2011

Experimental crescentic glomerulonephritis: a new bicongenic rat model

por D’Souza, Zelpha, McAdoo, Stephen P., Smith, Jennifer, Pusey, Charles D., Cook, H. Terence, Behmoaras, Jacques, Aitman, Timothy J.
Publicado 2013

Resequencing the susceptibility gene, ITGAM, identifies two functionally deleterious rare variants in systemic lupus erythematosus cases

por Roberts, Amy L, Thomas, Ellen RA, Bhosle, Shriram, Game, Laurence, Obraztsova, Olga, Aitman, Timothy J, Vyse, Timothy J, Rhodes, Benjamin
Publicado 2014

AP-1 Transcription Factor JunD Confers Protection from Accelerated Nephrotoxic Nephritis and Control Podocyte-Specific Vegfa Expression

por Cook, H. Terence, Tarzi, Ruth, D'Souza, Zelpha, Laurent, Gaelle, Lin, Wei-Chou, Aitman, Timothy J., Mechta-Grigoriou, Fatima, Behmoaras, Jacques
Publicado 2011

Role of Novel Rat-specific Fc Receptor in Macrophage Activation Associated with Crescentic Glomerulonephritis

por Page, Theresa H., D'Souza, Zelpha, Nakanishi, Satoshi, Serikawa, Tadao, Pusey, Charles D., Aitman, Timothy J., Cook, H. Terence, Behmoaras, Jacques
Publicado 2012

Genome-Wide Co-Expression Analysis in Multiple Tissues

por Grieve, Ian C., Dickens, Nicholas J., Pravenec, Michal, Kren, Vladimir, Hubner, Norbert, Cook, Stuart A., Aitman, Timothy J., Petretto, Enrico, Mangion, Jonathan
Publicado 2008

Genetic, physiological and comparative genomic studies of hypertension and insulin resistance in the spontaneously hypertensive rat

por Coan, Philip M., Hummel, Oliver, Garcia Diaz, Ana, Barrier, Marjorie, Alfazema, Neza, Norsworthy, Penny J., Pravenec, Michal, Petretto, Enrico, Hübner, Norbert, Aitman, Timothy J.
Publicado 2017

De novo mutations in autosomal recessive congenital malformations

por Black, Holly A., Parry, David, Atanur, Santosh S., Ross, David, Rose, Elaine, Russell, Helen, Stock, Sarah, Warner, Jon, Porteous, Mary, Aitman, Timothy J., Evans, Margaret J.
Publicado 2016

Acute Presentation and Persistent Glomerulonephritis Following Streptococcal Infection in a Patient With Heterozygous Complement Factor H–Related Protein 5 Deficiency

por Vernon, Katherine A., Goicoechea de Jorge, Elena, Hall, Angela E., Fremeaux-Bacchi, Veronique, Aitman, Timothy J., Cook, H. Terence, Hangartner, Robert, Koziell, Ania, Pickering, Matthew C.
Publicado 2012

Combined ChIP-Seq and transcriptome analysis identifies AP-1/JunD as a primary regulator of oxidative stress and IL-1β synthesis in macrophages

por Hull, Richard P, Srivastava, Prashant K, D’Souza, Zelpha, Atanur, Santosh S, Mechta-Grigoriou, Fatima, Game, Laurence, Petretto, Enrico, Cook, H Terence, Aitman, Timothy J, Behmoaras, Jacques
Publicado 2013

Systematic biases in DNA copy number originate from isolation procedures

por van Heesch, Sebastiaan, Mokry, Michal, Boskova, Veronika, Junker, Wade, Mehon, Rajdeep, Toonen, Pim, de Bruijn, Ewart, Shull, James D, Aitman, Timothy J, Cuppen, Edwin, Guryev, Victor
Publicado 2013

New Insights into the Genetic Control of Gene Expression using a Bayesian Multi-tissue Approach

por Petretto, Enrico, Bottolo, Leonardo, Langley, Sarah R., Heinig, Matthias, McDermott-Roe, Chris, Sarwar, Rizwan, Pravenec, Michal, Hübner, Norbert, Aitman, Timothy J., Cook, Stuart A., Richardson, Sylvia
Publicado 2010

Absolute measurement of the tissue origins of cell-free DNA in the healthy state and following paracetamol overdose

por Laurent, Danny, Semple, Fiona, Starkey Lewis, Philip J., Rose, Elaine, Black, Holly A., Coe, Jennifer, Forbes, Stuart J., Arends, Mark J., Dear, James W., Aitman, Timothy J.
Publicado 2020

Heritability and Tissue Specificity of Expression Quantitative Trait Loci

por Petretto, Enrico, Mangion, Jonathan, Dickens, Nicholas J, Cook, Stuart A, Kumaran, Mande K, Lu, Han, Fischer, Judith, Maatz, Henrike, Kren, Vladimir, Pravenec, Michal, Hubner, Norbert, Aitman, Timothy J
Publicado 2006

Identification and biochemical analysis of a novel APOB mutation that causes autosomal dominant hypercholesterolemia

por Thomas, Ellen R A, Atanur, Santosh S, Norsworthy, Penny J, Encheva, Vesela, Snijders, Ambrosius P, Game, Laurence, Vandrovcova, Jana, Siddiq, Afshan, Seed, Mary, Soutar, Anne K, Aitman, Timothy J
Publicado 2013

Changes in the Coding and Non-coding Transcriptome and DNA Methylome that Define the Schwann Cell Repair Phenotype after Nerve Injury

por Arthur-Farraj, Peter J., Morgan, Claire C., Adamowicz, Martyna, Gomez-Sanchez, Jose A., Fazal, Shaline V., Beucher, Anthony, Razzaghi, Bonnie, Mirsky, Rhona, Jessen, Kristjan R., Aitman, Timothy J.
Publicado 2017