Structural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralization

por Sun, Siyang, Xiang, Ye, Akahata, Wataru, Holdaway, Heather, Pal, Pankaj, Zhang, Xinzheng, Diamond, Michael S, Nabel, Gary J, Rossmann, Michael G
Publicado 2013

Reassessing therapeutic antibodies for neglected and tropical diseases

por Hooft van Huijsduijnen, Rob, Kojima, Somei, Carter, Dee, Okabe, Hisafumi, Sato, Akihide, Akahata, Wataru, Wells, Timothy N. C., Katsuno, Kei
Publicado 2020

A VLP vaccine for epidemic Chikungunya virus protects non-human primates against infection

por Akahata, Wataru, Yang, Zhi-yong, Andersen, Hanne, Sun, Siyang, Holdaway, Heather A., Kong, Wing-Pui, Lewis, Mark G., Higgs, Stephen, Rossmann, Michael G., Rao, Srinivas, Nabel, Gary J.
Publicado 2010

Development of a Novel Virus-Like Particle Vaccine Platform That Mimics the Immature Form of Alphavirus

por Urakami, Akane, Sakurai, Atsuko, Ishikawa, Momoko, Yap, Moh Lan, Flores-Garcia, Yevel, Haseda, Yasunari, Aoshi, Taiki, Zavala, Fidel P., Rossmann, Michael G., Kuno, Sachiko, Ueno, Ryuji, Akahata, Wataru
Publicado 2017

Development of a Highly Protective Combination Monoclonal Antibody Therapy against Chikungunya Virus

por Pal, Pankaj, Dowd, Kimberly A., Brien, James D., Edeling, Melissa A., Gorlatov, Sergey, Johnson, Syd, Lee, Iris, Akahata, Wataru, Nabel, Gary J., Richter, Mareike K. S., Smit, Jolanda M., Fremont, Daved H., Pierson, Theodore C., Heise, Mark T., Diamond, Michael S.
Publicado 2013

saRNA vaccine expressing membrane-anchored RBD elicits broad and durable immunity against SARS-CoV-2 variants of concern

por Komori, Mai, Nogimori, Takuto, Morey, Amber L., Sekida, Takashi, Ishimoto, Keiko, Hassett, Matthew R., Masuta, Yuji, Ode, Hirotaka, Tamura, Tomokazu, Suzuki, Rigel, Alexander, Jeff, Kido, Yasutoshi, Matsuda, Kenta, Fukuhara, Takasuke, Iwatani, Yasumasa, Yamamoto, Takuya, Smith, Jonathan F., Akahata, Wataru
Publicado 2023

Safety and immunogenicity of SARS-CoV-2 self-amplifying RNA vaccine expressing an anchored RBD: A randomized, observer-blind phase 1 study

por Akahata, Wataru, Sekida, Takashi, Nogimori, Takuto, Ode, Hirotaka, Tamura, Tomokazu, Kono, Kaoru, Kazami, Yoko, Washizaki, Ayaka, Masuta, Yuji, Suzuki, Rigel, Matsuda, Kenta, Komori, Mai, Morey, Amber L., Ishimoto, Keiko, Nakata, Misako, Hasunuma, Tomoko, Fukuhara, Takasuke, Iwatani, Yasumasa, Yamamoto, Takuya, Smith, Jonathan F., Sato, Nobuaki
Publicado 2023