Novel thiazolidinone-containing compounds, without the well-known sulphonamide zinc-binding group acting as human carbonic anhydrase IX inhibitors

por Güzel-Akdemir, Özlen, Angeli, Andrea, Demir, Kübra, Supuran, Claudiu T., Akdemir, Atilla
Publicado 2018

Novel Indole-Based Hydrazones as Potent Inhibitors of the α-class Carbonic Anhydrase from Pathogenic Bacterium Vibrio cholerae

por Demir-Yazıcı, Kübra, Güzel-Akdemir, Özlen, Angeli, Andrea, Supuran, Claudiu T., Akdemir, Atilla
Publicado 2020

Novel 2-indolinones containing a sulfonamide moiety as selective inhibitors of candida β-carbonic anhydrase enzyme

por Akdemir, Atilla, Angeli, Andrea, Göktaş, Füsun, Eraslan Elma, Pınar, Karalı, Nilgün, Supuran, Claudiu T.
Publicado 2019

Five- and Six-Membered Nitrogen-Containing Compounds as Selective Carbonic Anhydrase Activators

por Mollica, Adriano, Macedonio, Giorgia, Stefanucci, Azzurra, Carradori, Simone, Akdemir, Atilla, Angeli, Andrea, Supuran, Claudiu T.
Publicado 2017

Thiosemicarbazide-Substituted Coumarins as Selective Inhibitors of the Tumor Associated Human Carbonic Anhydrases IX and XII

por Gumus, Arzu, Bozdag, Murat, Akdemir, Atilla, Angeli, Andrea, Selleri, Silvia, Carta, Fabrizio, Supuran, Claudiu T.
Publicado 2022

Indole-Based Hydrazones Containing A Sulfonamide Moiety as Selective Inhibitors of Tumor-Associated Human Carbonic Anhydrase Isoforms IX and XII

por Demir-Yazıcı, Kübra, Bua, Silvia, Akgüneş, Nurgül Mutlu, Akdemir, Atilla, Supuran, Claudiu T., Güzel-Akdemir, Özlen
Publicado 2019

Development of Thiazolidinones as Fungal Carbonic Anhydrase Inhibitors

por Güzel-Akdemir, Özlen, Carradori, Simone, Grande, Rossella, Demir-Yazıcı, Kübra, Angeli, Andrea, Supuran, Claudiu T., Akdemir, Atilla
Publicado 2020

Tail-Approach-Based Design and Synthesis of Coumarin-Monoterpenes as Carbonic Anhydrase Inhibitors and Anticancer Agents

por Zengin Kurt, Belma, Celebi, Gulsen, Ozturk Civelek, Dilek, Angeli, Andrea, Akdemir, Atilla, Sonmez, Fatih, Supuran, Claudiu T.
Publicado 2023

Anti-SARS-CoV-2 and cytotoxic activity of two marine alkaloids from green alga Caulerpa cylindracea Sonder in the Dardanelles

por Erol, Ebru, Orhan, Muge Didem, Avsar, Timucin, Akdemir, Atilla, Okudan, Emine Sukran, Alim Toraman, Gulbahar Ozge, Topcu, Gulacti
Publicado 2022

Azole-Based Compounds That Are Active against Candida Biofilm: In Vitro, In Vivo and In Silico Studies

por Carradori, Simone, Ammazzalorso, Alessandra, De Filippis, Barbara, Şahin, Ahmet Fatih, Akdemir, Atilla, Orekhova, Anastasia, Bonincontro, Graziana, Simonetti, Giovanna
Publicado 2022

Fibrate-based N-acylsulphonamides targeting carbonic anhydrases: synthesis, biochemical evaluation, and docking studies

por Ammazzalorso, Alessandra, Carradori, Simone, Angeli, Andrea, Akdemir, Atilla, De Filippis, Barbara, Fantacuzzi, Marialuigia, Giampietro, Letizia, Maccallini, Cristina, Amoroso, Rosa, Supuran, Claudiu T.
Publicado 2019

Identification of novel α7 nicotinic receptor ligands by in silico screening against the crystal structure of a chimeric α7 receptor ligand binding domain

por Akdemir, Atilla, Edink, Ewald, Thompson, Andrew J., Lummis, Sarah C.R., Kooistra, Albert J., de Graaf, Chris, de Esch, Iwan J.P.
Publicado 2012

Open saccharin-based secondary sulfonamides as potent and selective inhibitors of cancer-related carbonic anhydrase IX and XII isoforms

por D’Ascenzio, Melissa, Guglielmi, Paolo, Carradori, Simone, Secci, Daniela, Florio, Rosalba, Mollica, Adriano, Ceruso, Mariangela, Akdemir, Atilla, Sobolev, Anatoly P., Supuran, Claudiu T.
Publicado 2016

New azolyl-derivatives as multitargeting agents against breast cancer and fungal infections: synthesis, biological evaluation and docking study

por Maccallini, Cristina, Gallorini, Marialucia, Sisto, Francesca, Akdemir, Atilla, Ammazzalorso, Alessandra, De Filippis, Barbara, Fantacuzzi, Marialuigia, Giampietro, Letizia, Carradori, Simone, Cataldi, Amelia, Amoroso, Rosa
Publicado 2021

Design, synthesis and biological activity of selective hCAs inhibitors based on 2-(benzylsulfinyl)benzoic acid scaffold

por Rotondi, Giulia, Guglielmi, Paolo, Carradori, Simone, Secci, Daniela, De Monte, Celeste, De Filippis, Barbara, Maccallini, Cristina, Amoroso, Rosa, Cirilli, Roberto, Akdemir, Atilla, Angeli, Andrea, Supuran, Claudiu T.
Publicado 2019

Carbonic Anhydrase Inhibitors Targeting Metabolism and Tumor Microenvironment

por Angeli, Andrea, Carta, Fabrizio, Nocentini, Alessio, Winum, Jean-Yves, Zalubovskis, Raivis, Akdemir, Atilla, Onnis, Valentina, Eldehna, Wagdy M., Capasso, Clemente, Simone, Giuseppina De, Monti, Simona Maria, Carradori, Simone, Donald, William A., Dedhar, Shoukat, Supuran, Claudiu T.
Publicado 2020

The neutralization effect of montelukast on SARS-CoV-2 is shown by multiscale in silico simulations and combined in vitro studies

por Durdagi, Serdar, Avsar, Timucin, Orhan, Muge Didem, Serhatli, Muge, Balcioglu, Bertan Koray, Ozturk, Hasan Umit, Kayabolen, Alisan, Cetin, Yuksel, Aydinlik, Seyma, Bagci-Onder, Tugba, Tekin, Saban, Demirci, Hasan, Guzel, Mustafa, Akdemir, Atilla, Calis, Seyma, Oktay, Lalehan, Tolu, Ilayda, Butun, Yasar Enes, Erdemoglu, Ece, Olkan, Alpsu, Tokay, Nurettin, Işık, Şeyma, Ozcan, Aysenur, Acar, Elif, Buyukkilic, Sehriban, Yumak, Yesim
Publicado 2022