Bayesian inference of origin firing time distributions, origin interference and licencing probabilities from Next Generation Sequencing data

por Bazarova, Alina, Nieduszynski, Conrad A, Akerman, Ildem, Burroughs, Nigel J
Publicado 2019

βlinc1 encodes a long noncoding RNA that regulates islet β-cell formation and function

por Arnes, Luis, Akerman, Ildem, Balderes, Dina A., Ferrer, Jorge, Sussel, Lori
Publicado 2016

Peripheral blood mononuclear cells preferentially activate 11-oxygenated androgens

por Schiffer, Lina, Bossey, Alicia, Kempegowda, Punith, Taylor, Angela E, Akerman, Ildem, Scheel-Toellner, Dagmar, Storbeck, Karl-Heinz, Arlt, Wiebke
Publicado 2021

Neonatal diabetes mutations disrupt a chromatin pioneering function that activates the human insulin gene

por Akerman, Ildem, Maestro, Miguel Angel, De Franco, Elisa, Grau, Vanessa, Flanagan, Sarah, García-Hurtado, Javier, Mittler, Gerhard, Ravassard, Philippe, Piemonti, Lorenzo, Ellard, Sian, Hattersley, Andrew T., Ferrer, Jorge
Publicado 2021

A predictable conserved DNA base composition signature defines human core DNA replication origins

por Akerman, Ildem, Kasaai, Bahar, Bazarova, Alina, Sang, Pau Biak, Peiffer, Isabelle, Artufel, Marie, Derelle, Romain, Smith, Gabrielle, Rodriguez-Martinez, Marta, Romano, Manuela, Kinet, Sandrina, Tino, Peter, Theillet, Charles, Taylor, Naomi, Ballester, Benoit, Méchali, Marcel
Publicado 2020

Prolyl-4-hydroxylase 3 maintains β cell glucose metabolism during fatty acid excess in mice

por Nasteska, Daniela, Cuozzo, Federica, Viloria, Katrina, Johnson, Elspeth M., Thakker, Alpesh, Bany Bakar, Rula, Westbrook, Rebecca L., Barlow, Jonathan P., Hoang, Monica, Joseph, Jamie W., Lavery, Gareth G., Akerman, Ildem, Cantley, James, Hodson, Leanne, Tennant, Daniel A., Hodson, David J.
Publicado 2021

PDX1(LOW) MAFA(LOW) β-cells contribute to islet function and insulin release

por Nasteska, Daniela, Fine, Nicholas H. F., Ashford, Fiona B., Cuozzo, Federica, Viloria, Katrina, Smith, Gabrielle, Dahir, Aisha, Dawson, Peter W. J., Lai, Yu-Chiang, Bastidas-Ponce, Aimée, Bakhti, Mostafa, Rutter, Guy A., Fiancette, Remi, Nano, Rita, Piemonti, Lorenzo, Lickert, Heiko, Zhou, Qiao, Akerman, Ildem, Hodson, David J.
Publicado 2021

Systemic and adipocyte transcriptional and metabolic dysregulation in idiopathic intracranial hypertension

por Westgate, Connar S.J., Botfield, Hannah F., Alimajstorovic, Zerin, Yiangou, Andreas, Walsh, Mark, Smith, Gabrielle, Singhal, Rishi, Mitchell, James L., Grech, Olivia, Markey, Keira A., Hebenstreit, Daniel, Tennant, Daniel A., Tomlinson, Jeremy W., Mollan, Susan P., Ludwig, Christian, Akerman, Ildem, Lavery, Gareth G., Sinclair, Alexandra J.
Publicado 2021

Author Correction: PDX1(LOW) MAFA(LOW) β-cells contribute to islet function and insulin release

por Nasteska, Daniela, Fine, Nicholas H. F., Ashford, Fiona B., Cuozzo, Federica, Viloria, Katrina, Smith, Gabrielle, Dahir, Aisha, Dawson, Peter W. J., Lai, Yu-Chiang, Bastidas-Ponce, Aimée, Bakhti, Mostafa, Rutter, Guy A., Fiancette, Remi, Nano, Rita, Piemonti, Lorenzo, Lickert, Heiko, Zhou, Qiao, Akerman, Ildem, Hodson, David J.
Publicado 2021

Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD(+) Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures

por Elhassan, Yasir S., Kluckova, Katarina, Fletcher, Rachel S., Schmidt, Mark S., Garten, Antje, Doig, Craig L., Cartwright, David M., Oakey, Lucy, Burley, Claire V., Jenkinson, Ned, Wilson, Martin, Lucas, Samuel J.E., Akerman, Ildem, Seabright, Alex, Lai, Yu-Chiang, Tennant, Daniel A., Nightingale, Peter, Wallis, Gareth A., Manolopoulos, Konstantinos N., Brenner, Charles, Philp, Andrew, Lavery, Gareth G.
Publicado 2019

Argonaute2 Mediates Compensatory Expansion of the Pancreatic β Cell

por Tattikota, Sudhir G., Rathjen, Thomas, McAnulty, Sarah J., Wessels, Hans-Hermann, Akerman, Ildem, van de Bunt, Martijn, Hausser, Jean, Esguerra, Jonathan L.S., Musahl, Anne, Pandey, Amit K., You, Xintian, Chen, Wei, Herrera, Pedro L., Johnson, Paul R., O’Carroll, Donal, Eliasson, Lena, Zavolan, Mihaela, Gloyn, Anna L., Ferrer, Jorge, Shalom-Feuerstein, Ruby, Aberdam, Daniel, Poy, Matthew N.
Publicado 2014

Human Pancreatic β Cell lncRNAs Control Cell-Specific Regulatory Networks

por Akerman, Ildem, Tu, Zhidong, Beucher, Anthony, Rolando, Delphine M.Y., Sauty-Colace, Claire, Benazra, Marion, Nakic, Nikolina, Yang, Jialiang, Wang, Huan, Pasquali, Lorenzo, Moran, Ignasi, Garcia-Hurtado, Javier, Castro, Natalia, Gonzalez-Franco, Roser, Stewart, Andrew F., Bonner, Caroline, Piemonti, Lorenzo, Berney, Thierry, Groop, Leif, Kerr-Conte, Julie, Pattou, Francois, Argmann, Carmen, Schadt, Eric, Ravassard, Philippe, Ferrer, Jorge
Publicado 2017

Vitamin-D-Binding Protein Contributes to the Maintenance of α Cell Function and Glucagon Secretion

por Viloria, Katrina, Nasteska, Daniela, Briant, Linford J.B., Heising, Silke, Larner, Dean P., Fine, Nicholas H.F., Ashford, Fiona B., da Silva Xavier, Gabriela, Ramos, Maria Jiménez, Hasib, Annie, Cuozzo, Federica, Manning Fox, Jocelyn E., MacDonald, Patrick E., Akerman, Ildem, Lavery, Gareth G., Flaxman, Christine, Morgan, Noel G., Richardson, Sarah J., Hewison, Martin, Hodson, David J.
Publicado 2020

Pancreatic islet enhancer clusters enriched in type 2 diabetes risk–associated variants

por Pasquali, Lorenzo, Gaulton, Kyle J., Rodríguez-Seguí, Santiago A., Mularoni, Loris, Miguel-Escalada, Irene, Akerman, İldem, Tena, Juan J., Morán, Ignasi, Gómez-Marín, Carlos, van de Bunt, Martijn, Ponsa-Cobas, Joan, Castro, Natalia, Nammo, Takao, Cebola, Inês, García-Hurtado, Javier, Maestro, Miguel Angel, Pattou, François, Piemonti, Lorenzo, Berney, Thierry, Gloyn, Anna L., Ravassard, Philippe, Skarmeta, José Luis Gómez, Müller, Ferenc, McCarthy, Mark I., Ferrer, Jorge
Publicado 2014