Improved detection of differentially represented DNA barcodes for high‐throughput clonal phenomics

por Akimov, Yevhen, Bulanova, Daria, Timonen, Sanna, Wennerberg, Krister, Aittokallio, Tero
Publicado 2020

Seed-effect modeling improves the consistency of genome-wide loss-of-function screens and identifies synthetic lethal vulnerabilities in cancer cells

por Jaiswal, Alok, Peddinti, Gopal, Akimov, Yevhen, Wennerberg, Krister, Kuznetsov, Sergey, Tang, Jing, Aittokallio, Tero
Publicado 2017

CRISPRi screening reveals regulators of tau pathology shared between exosomal and vesicle-free tau

por Polanco, Juan Carlos, Akimov, Yevhen, Fernandes, Avinash, Briner, Adam, Hand, Gabriel Rhys, van Roijen, Marloes, Balistreri, Giuseppe, Götz, Jürgen
Publicado 2022

Orphan G protein-coupled receptor GPRC5A modulates integrin β1-mediated epithelial cell adhesion

por Bulanova, Daria R., Akimov, Yevhen A., Rokka, Anne, Laajala, Teemu D., Aittokallio, Tero, Kouvonen, Petri, Pellinen, Teijo, Kuznetsov, Sergey G.
Publicado 2017

Multi‐modal meta‐analysis of cancer cell line omics profiles identifies ECHDC1 as a novel breast tumor suppressor

por Jaiswal, Alok, Gautam, Prson, Pietilä, Elina A, Timonen, Sanna, Nordström, Nora, Akimov, Yevhen, Sipari, Nina, Tanoli, Ziaurrehman, Fleischer, Thomas, Lehti, Kaisa, Wennerberg, Krister, Aittokallio, Tero
Publicado 2021

P1228: GENOME-WIDE CRISPR-CAS9 SCREENING IDENTIFIES THERAPEUTIC TARGETS FOR MATURE T-CELL MALIGNANCIES

por Timonen, Sanna, Rebecca Gasparini, Vanessa, Piekkari, Ella, Dufva, Olli, Awad, Shady, Akimov, Yevhen, von Jan, Jana, Braun, Till, Ianevski, Aleksandr, Kankainen, Matti, Klievink, Jay, Herling, Marco, Aittokallio, Tero, Mustjoki, Satu
Publicado 2023

Network pharmacology modeling identifies synergistic Aurora B and ZAK interaction in triple-negative breast cancer

por Tang, Jing, Gautam, Prson, Gupta, Abhishekh, He, Liye, Timonen, Sanna, Akimov, Yevhen, Wang, Wenyu, Szwajda, Agnieszka, Jaiswal, Alok, Turei, Denes, Yadav, Bhagwan, Kankainen, Matti, Saarela, Jani, Saez-Rodriguez, Julio, Wennerberg, Krister, Aittokallio, Tero
Publicado 2019

Chemical, Physical and Biological Triggers of Evolutionary Conserved Bcl-xL-Mediated Apoptosis

por Ianevski, Aleksandr, Kulesskiy, Evgeny, Krpina, Klara, Lou, Guofeng, Aman, Yahyah, Bugai, Andrii, Aasumets, Koit, Akimov, Yevhen, Bulanova, Daria, Gildemann, Kiira, Arutyunyan, Albert F., Susova, Olga Yu., Zhuze, Alexei L., Ji, Ping, Wang, Wei, Holien, Toril, Bugge, Marit, Zusinaite, Eva, Oksenych, Valentyn, Lysvand, Hilde, Gerhold, Joachim M., Bjørås, Magnar, Johansen, Pål, Waage, Anders, Heckman, Caroline A., Fang, Evandro F., Kainov, Denis E.
Publicado 2020

Antiviral Properties of Chemical Inhibitors of Cellular Anti-Apoptotic Bcl-2 Proteins

por Bulanova, Daria, Ianevski, Aleksandr, Bugai, Andrii, Akimov, Yevhen, Kuivanen, Suvi, Paavilainen, Henrik, Kakkola, Laura, Nandania, Jatin, Turunen, Laura, Ohman, Tiina, Ala-Hongisto, Hanna, Pesonen, Hanna M., Kuisma, Marika S., Honkimaa, Anni, Walton, Emma L., Oksenych, Valentyn, Lorey, Martina B., Guschin, Dmitry, Shim, Jungmin, Kim, Jinhee, Than, Thoa T., Chang, So Young, Hukkanen, Veijo, Kulesskiy, Evgeny, Marjomaki, Varpu S., Julkunen, Ilkka, Nyman, Tuula A., Matikainen, Sampsa, Saarela, Jani S., Sane, Famara, Hober, Didier, Gabriel, Gülsah, De Brabander, Jef K., Martikainen, Miika, Windisch, Marc P., Min, Ji-Young, Bruzzone, Roberto, Aittokallio, Tero, Vähä-Koskela, Markus, Vapalahti, Olli, Pulk, Arto, Velagapudi, Vidya, Kainov, Denis E.
Publicado 2017