What causes amyotrophic lateral sclerosis?

por Martin, Sarah, Al Khleifat, Ahmad, Al-Chalabi, Ammar
Publicado 2017

A standard operating procedure for King’s ALS clinical staging

por Balendra, Rubika, Al Khleifat, Ahmad, Fang, Ton, Al-Chalabi, Ammar
Publicado 2019

DNAscan2: a versatile, scalable, and user-friendly analysis pipeline for human next-generation sequencing data

por Marriott, Heather, Kabiljo, Renata, Al Khleifat, Ahmad, Dobson, Richard J, Al-Chalabi, Ammar, Iacoangeli, Alfredo
Publicado 2023

Does genetic anticipation occur in familial Alexander disease?

por Hunt, Camille K., Al Khleifat, Ahmad, Burchill, Ella, Ederle, Joerg, Al-Chalabi, Ammar, Sreedharan, Jemeen
Publicado 2021

Stage at which riluzole treatment prolongs survival in patients with amyotrophic lateral sclerosis: a retrospective analysis of data from a dose-ranging study

por Fang, Ton, Al Khleifat, Ahmad, Meurgey, Jacques-Henri, Jones, Ashley, Leigh, P Nigel, Bensimon, Gilbert, Al-Chalabi, Ammar
Publicado 2018

VariantSurvival: a tool to identify genotype–treatment response

por Krannich, Thomas, Sarrias, Marina Herrera, Ben Aribi, Hiba, Shokrof, Moustafa, Iacoangeli, Alfredo, Al-Chalabi, Ammar, Sedlazeck, Fritz J., Busby, Ben, Al Khleifat, Ahmad
Publicado 2023

An assessment of bioinformatics tools for the detection of human endogenous retroviral insertions in short-read genome sequencing data

por Bowles, Harry, Kabiljo, Renata, Al Khleifat, Ahmad, Jones, Ashley, Quinn, John P., Dobson, Richard J. B., Swanson, Chad M., Al-Chalabi, Ammar, Iacoangeli, Alfredo
Publicado 2023

Comparison of the King’s and MiToS staging systems for ALS

por Fang, Ton, Al Khleifat, Ahmad, Stahl, Daniel R, Lazo La Torre, Claudia, Murphy, Caroline, Young, Carolyn, Shaw, Pamela J, Leigh, P Nigel, Al-Chalabi, Ammar
Publicado 2017

Harnessing Transcriptomic Signals for Amyotrophic Lateral Sclerosis to Identify Novel Drugs and Enhance Risk Prediction

por Pain, Oliver, Jones, Ashley, Al Khleifat, Ahmad, Agarwal, Devika, Hramyka, Dzmitry, Karoui, Hajer, Kubica, Jędrzej, Llewellyn, David J., Ranson, Janice M., Yao, Zhi, Iacoangeli, Alfredo, Al-Chalabi, Ammar
Publicado 2023

RetroSnake: A modular pipeline to detect human endogenous retroviruses in genome sequencing data

por Kabiljo, Renata, Bowles, Harry, Marriott, Heather, Jones, Ashley R., Bouton, Clement R., Dobson, Richard J.B., Quinn, John P., Al Khleifat, Ahmad, Swanson, Chad M., Al-Chalabi, Ammar, Iacoangeli, Alfredo
Publicado 2022

UK case control study of smoking and risk of amyotrophic lateral sclerosis

por Opie-Martin, Sarah, Jones, Ashley, Iacoangeli, Alfredo, Al-Khleifat, Ahmad, Oumar, Mohamed, Shaw, Pamela J., Shaw, Chris E., Morrison, Karen E., Wootton, Robyn E., Davey-Smith, George, Pearce, Neil, Al-Chalabi, Ammar
Publicado 2020

ALSgeneScanner: a pipeline for the analysis and interpretation of DNA sequencing data of ALS patients

por Iacoangeli, Alfredo, Al Khleifat, Ahmad, Sproviero, William, Shatunov, Aleksey, Jones, Ashley R., Opie-Martin, Sarah, Naselli, Ersilia, Topp, Simon D., Fogh, Isabella, Hodges, Angela, Dobson, Richard J., Newhouse, Stephen J., Al-Chalabi, Ammar
Publicado 2019

C9orf72 intermediate expansions of 24–30 repeats are associated with ALS

por Iacoangeli, Alfredo, Al Khleifat, Ahmad, Jones, Ashley R., Sproviero, William, Shatunov, Aleksey, Opie-Martin, Sarah, Morrison, Karen E., Shaw, Pamela J., Shaw, Christopher E., Fogh, Isabella, Dobson, Richard J., Newhouse, Stephen J., Al-Chalabi, Ammar
Publicado 2019

The impact of age on genetic testing decisions in amyotrophic lateral sclerosis

por Mehta, Puja R, Iacoangeli, Alfredo, Opie-Martin, Sarah, van Vugt, Joke J F A, Al Khleifat, Ahmad, Bredin, Andrea, Ossher, Lynn, Andersen, Peter M, Hardiman, Orla, Mehta, Arpan R, Fratta, Pietro, Talbot, Kevin, Al-Chalabi, Ammar
Publicado 2022

Younger age of onset in familial amyotrophic lateral sclerosis is a result of pathogenic gene variants, rather than ascertainment bias

por Mehta, Puja R, Jones, Ashley R, Opie-Martin, Sarah, Shatunov, Aleksey, Iacoangeli, Alfredo, Al Khleifat, Ahmad, Smith, Bradley N, Topp, Simon, Morrison, Karen E, Shaw, Pamela J, Shaw, Christopher E, Morgan, Sarah, Pittman, Alan, Al-Chalabi, Ammar
Publicado 2019

Telomere length is greater in ALS than in controls: a whole genome sequencing study

por Al Khleifat, Ahmad, Iacoangeli, Alfredo, Shatunov, Aleksey, Fang, Ton, Sproviero, William, Jones, Ashley R., Opie-Martin, Sarah, Morrison, Karen E., Shaw, Pamela J., Shaw, Christopher E., Powell, John F., Dobson, Richard, Newhouse, Steven J., Al-Chalabi, Ammar
Publicado 2019

Harnessing the potential of machine learning and artificial intelligence for dementia research

por Ranson, Janice M., Bucholc, Magda, Lyall, Donald, Newby, Danielle, Winchester, Laura, Oxtoby, Neil P., Veldsman, Michele, Rittman, Timothy, Marzi, Sarah, Skene, Nathan, Al Khleifat, Ahmad, Foote, Isabelle F., Orgeta, Vasiliki, Kormilitzin, Andrey, Lourida, Ilianna, Llewellyn, David J.
Publicado 2023

Artificial Intelligence for Dementia Research Methods Optimization

por Bucholc, Magda, James, Charlotte, Al Khleifat, Ahmad, Badhwar, AmanPreet, Clarke, Natasha, Dehsarvi, Amir, Madan, Christopher R., Marzi, Sarah J., Shand, Cameron, Schilder, Brian M., Tamburin, Stefano, Tantiangco, Hanz M., Lourida, Ilianna, Llewellyn, David J., Ranson, Janice M.
Publicado 2023

Molecular dynamics analysis of superoxide dismutase 1 mutations suggests decoupling between mechanisms underlying ALS onset and progression

por Kalia, Munishikha, Miotto, Mattia, Ness, Deborah, Opie-Martin, Sarah, Spargo, Thomas P., Di Rienzo, Lorenzo, Biagini, Tommaso, Petrizzelli, Francesco, Al Khleifat, Ahmad, Kabiljo, Renata, Mazza, Tommaso, Ruocco, Giancarlo, Milanetti, Edoardo, Dobson, Richard JB, Al-Chalabi, Ammar, Iacoangeli, Alfredo
Publicado 2023

A comprehensive analysis of rare genetic variation in amyotrophic lateral sclerosis in the UK

por Morgan, Sarah, Shatunov, Aleksey, Sproviero, William, Jones, Ashley R., Shoai, Maryam, Hughes, Deborah, Al Khleifat, Ahmad, Malaspina, Andrea, Morrison, Karen E., Shaw, Pamela J., Shaw, Christopher E., Sidle, Katie, Orrell, Richard W., Fratta, Pietro, Hardy, John, Pittman, Alan, Al-Chalabi, Ammar
Publicado 2017