Aryl hydrocarbon receptor/cytochrome P450 1A1 pathway mediates breast cancer stem cells expansion through PTEN inhibition and β-Catenin and Akt activation

por Al-Dhfyan, Abdullah, Alhoshani, Ali, Korashy, Hesham M.
Publicado 2017

Erratum to: Aryl hydrocarbon receptor/cytochrome P450 1A1 pathway mediates breast cancer stem cells expansion through PTEN inhibition and β-Catenin and Akt activation

por Al-Dhfyan, Abdullah, Alhoshani, Ali, Korashy, Hesham M.
Publicado 2017

Targeting Cancer Stem Cells with Novel 4-(4-Substituted phenyl)-5-(3,4,5-trimethoxy/3,4-dimethoxy)-benzoyl-3,4-dihydropyrimidine-2(1H)-one/thiones

por Bhat, Mashooq Ahmad, Al-Dhfyan, Abdullah, Al-Omar, Mohamed A.
Publicado 2016

Schiff bases of indoline-2,3-dione (isatin) with potential antiproliferative activity

por Aboul-Fadl, Tarek, Radwan, Awwad A, Attia, Mohamed I, Al-Dhfyan, Abdullah, Abdel-Aziz, Hatem A
Publicado 2012

Lead Optimization of 2-Cyclohexyl-N-[(Z)-(3-methoxyphenyl/3-hydroxyphenyl) methylidene]hydrazinecarbothioamides for Targeting the HER-2 Overexpressed Breast Cancer Cell Line SKBr-3

por Bhat, Mashooq A., Al-Dhfyan, Abdullah, Naglah, Ahmed M., Ali Khan, Azmat, Al-Omar, Mohamed A.
Publicado 2015

ChCl: Gly (DESs) Promote Environmentally Benign Synthesis of Xanthene Derivatives and Their Antitubercular Activity

por Bhat, Mashooq A., Naglah, Ahmed M., Akber Ansari, Siddique, Al-Tuwajiria, Hanaa M., Al-Dhfyan, Abdullah
Publicado 2021

Synthesis, Crystal Study, and Anti-Proliferative Activity of Some 2-Benzimidazolylthioacetophenones towards Triple-Negative Breast Cancer MDA-MB-468 Cells as Apoptosis-Inducing Age...

por Abdel-Aziz, Hatem A., Eldehna, Wagdy M., Ghabbour, Hazem, Al-Ansary, Ghada H., Assaf, Areej M., Al-Dhfyan, Abdullah
Publicado 2016

In vivo and in vitro studies evaluating the chemopreventive effect of metformin on the aryl hydrocarbon receptor-mediated breast carcinogenesis

por Alhoshani, Ali, Alotaibi, Moureq, As Sobeai, Homood M., Alharbi, Naif, Alhazzani, Khalid, Al-Dhfyan, Abdullah, Alanazi, Fawaz E., Korashy, Hesham M.
Publicado 2021

Crosstalk between aryl hydrocarbon receptor (AhR) and BCL-2 pathways suggests the use of AhR antagonist to maintain normal differentiation state of mammary epithelial cells during...

por Al-Dhfyan, Abdullah, Alaiya, Ayodele, Al-Mohanna, Falah, Attwa, Mohamed W, AlAsmari, Abdullah F, Bakheet, Saleh A, Korashy, Hesham M.
Publicado 2022

Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies

por Alanazi, Fawaz E., As Sobeai, Homood M., Alhazzani, Khalid, Al-Dhfyan, Abdullah, Alshammari, Musaad A, Alotaibi, Moureq, Al-hosaini, Khaled, Korashy, Hesham M., Alhoshani, Ali
Publicado 2022

Synthesis and in vitro anti-proliferative activity of some novel isatins conjugated with quinazoline/phthalazine hydrazines against triple-negative breast cancer MDA-MB-231 cells a...

por Eldehna, Wagdy M., Almahli, Hadia, Al-Ansary, Ghada H., Ghabbour, Hazem A., Aly, Mohamed H., Ismael, Omnia E., Al-Dhfyan, Abdullah, Abdel-Aziz, Hatem A.
Publicado 2017

Synthesis, anticancer and apoptosis-inducing activities of quinazoline–isatin conjugates: epidermal growth factor receptor-tyrosine kinase assay and molecular docking studies

por El-Azab, Adel S., Al-Dhfyan, Abdullah, Abdel-Aziz, Alaa A.-M., Abou-Zeid, Laila A., Alkahtani, Hamad M., Al-Obaid, Abdulrahman M., Al-Gendy, Manal A.
Publicado 2017

Cancer stem cells CD133 inhibition and cytotoxicity of certain 3-phenylthiazolo[3,2-a]benzimidazoles: design, direct synthesis, crystal study and in vitro biological evaluation

por Al-Ansary, Ghada H., Eldehna, Wagdy M., Ghabbour, Hazem A., Al-Rashood, Sara T. A., Al-Rashood, Khalid A., Eladwy, Radwa A., Al-Dhfyan, Abdullah, Kabil, Maha M., Abdel-Aziz, Hatem A.
Publicado 2017