Stem cells for the treatment of glioblastoma: a 20-year perspective

por Calinescu, Anda-Alexandra, Kauss, McKenzie C, Sultan, Zain, Al-Holou, Wajd N, O’Shea, Sue K
Publicado 2021

H3K27M-mutant diffuse midline glioma with extensive intratumoral microthrombi in a young adult with COVID-19-associated coagulopathy

por Pun, Matthew, Haggerty-Skeans, James, Pratt, Drew, Fudym, Yelena, Al-Holou, Wajd N., Camelo-Piragua, Sandra, Venneti, Sriram
Publicado 2020

Symptomatic CNS Radiation Necrosis Requiring Neurosurgical Resection During Treatment with Lorlatinib in ALK-Rearranged NSCLC: A Report of Two Cases

por Zhu, Viola W, Nagasaka, Misako, Kubota, Takafumi, Raval, Kunil, Robinette, Natasha, Armas, Octavio, Al-Holou, Wajd, Ou, Sai-Hong Ignatius
Publicado 2020

DDRE-19. PHASE 0/I TRIAL OF MYCOPHENOLATE MOFETIL COMBINED WITH RADIATION TO OVERCOME GLIOBLASTOMA TREATMENT RESISTANCE BY TARGETING DE-NOVO PURINE METABOLISM

por Umemura, Yoshie, Sun, Yilun, Junck, Larry, Leung, Denise, Kim, Michelle, Al-Holou, Wajd, Sagher, Oren, Heth, Jason, Lyssiotis, Costas, Marini, Bernard, Lawrence, Theodore, Wahl, Daniel
Publicado 2021

Uncovering Spatiotemporal Heterogeneity of High-Grade Gliomas: From Disease Biology to Therapeutic Implications

por Comba, Andrea, Faisal, Syed M., Varela, Maria Luisa, Hollon, Todd, Al-Holou, Wajd N., Umemura, Yoshie, Nunez, Felipe J., Motsch, Sebastien, Castro, Maria G., Lowenstein, Pedro R.
Publicado 2021

NEIM-08 A PHASE II STUDY OF MULTIPARAMETRIC MR-GUIDED HIGH DOSE ADAPTIVE RADIOTHERAPY WITH CONCURRENT TEMOZOLOMIDE IN PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA

por Kim, Michelle, Aryal, Madhava, Rosen, Benjamin, Parmar, Hemant, You, Daekeun, Junck, Larry, Leung, Denise, Umemura, Yoshie, Heth, Jason, Al-Holou, Wajd, Hollon, Todd, Wahl, Daniel, Lawrence, Theodore, Cao, Yue
Publicado 2022

LMD-09. Outcomes and symptom benefit from palliative radiotherapy for leptomeningeal disease in breast cancer patients

por Takayesu, Jamie, Sapir, Eli, Xie, Jiaheng, Sun, Yilun, Morikawa, Aki, Junck, Larry, Leung, Denise, Umemura, Yoshie, Heth, Jason, Al-Holou, Wajd, Wahl, Daniel, Lawrence, Theodore, Mayo, Charles, Hayman, James, Kim, Michelle
Publicado 2021

Generation of 3D ex vivo mouse- and patient-derived glioma explant slice model for integration of confocal time-lapse imaging and spatial analysis

por Comba, Andrea, Varela, Maria Luisa, Faisal, Syed M., Abel, Clifford C., Argento, Anna E., Al-Holou, Wajd N., Hollon, Todd C., Perelman, Jacqueline D., Dunn, Patrick J., Motsch, Sebastien, Castro, Maria G., Lowenstein, Pedro R.
Publicado 2023

MRI-Guided Stereotactic Biopsy of Murine GBM for Spatiotemporal Molecular Genomic Assessment

por Galbán, Stefanie, Al-Holou, Wajd N., Wang, Hanxiao, Welton, Amanda R., Heist, Kevin, Kathy Hu, Xin, Verhaak, Roeland GW, Zhu, Yuan, Espinoza, Carlos, Chenevert, Thomas L., Hoff, Ben A., Galbán, Craig J., Ross, Brian D.
Publicado 2017

Spatiotemporal analysis of glioma heterogeneity reveals COL1A1 as an actionable target to disrupt tumor progression

por Comba, Andrea, Faisal, Syed M., Dunn, Patrick J., Argento, Anna E., Hollon, Todd C., Al-Holou, Wajd N., Varela, Maria Luisa, Zamler, Daniel B., Quass, Gunnar L., Apostolides, Pierre F., Abel, Clifford, Brown, Christine E., Kish, Phillip E., Kahana, Alon, Kleer, Celina G., Motsch, Sebastien, Castro, Maria G., Lowenstein, Pedro R.
Publicado 2022

Subclonal evolution and expansion of spatially distinct THY1-positive cells is associated with recurrence in glioblastoma

por Al-Holou, Wajd N., Wang, Hanxiao, Ravikumar, Visweswaran, Shankar, Sunita, Oneka, Morgan, Fehmi, Ziad, Verhaak, Roel GW, Kim, Hoon, Pratt, Drew, Camelo-Piragua, Sandra, Speers, Corey, Wahl, Daniel R, Hollon, Todd, Sagher, Oren, Heth, Jason A, Muraszko, Karin M., Lawrence, Theodore S., de Carvalho, Ana C, Mikkelsen, Tom, Rao, Arvind, Rehemtulla, Alnawaz
Publicado 2023

A validated integrated clinical and molecular glioblastoma long-term survival-predictive nomogram

por Ferguson, Sherise D, Hodges, Tiffany R, Majd, Nazanin K, Alfaro-Munoz, Kristin, Al-Holou, Wajd N, Suki, Dima, de Groot, John F, Fuller, Gregory N, Xue, Lee, Li, Miao, Jacobs, Carmen, Rao, Ganesh, Colen, Rivka R, Xiu, Joanne, Verhaak, Roel, Spetzler, David, Khasraw, Mustafa, Sawaya, Raymond, Long, James P, Heimberger, Amy B
Publicado 2020

G-CSF secreted by mutant IDH1 glioma stem cells abolishes myeloid cell immunosuppression and enhances the efficacy of immunotherapy

por Alghamri, Mahmoud S., McClellan, Brandon L., Avvari, Ruthvik P., Thalla, Rohit, Carney, Stephen, Hartlage, Margaret S., Haase, Santiago, Ventosa, Maria, Taher, Ayman, Kamran, Neha, Zhang, Li, Faisal, Syed Mohd, Núñez, Felipe J., Garcia-Fabiani, María Belén, Al-Holou, Wajd N., Orringer, Daniel, Hervey-Jumper, Shawn, Heth, Jason, Patil, Parag G., Eddy, Karen, Merajver, Sofia D., Ulintz, Peter J., Welch, Joshua, Gao, Chao, Liu, Jialin, Núñez, Gabriel, Hambardzumyan, Dolores, Lowenstein, Pedro R., Castro, Maria G.
Publicado 2021