Arginine Metabolism in Myeloid Cells Shapes Innate and Adaptive Immunity

por Rodriguez, Paulo C., Ochoa, Augusto C., Al-Khami, Amir A.
Publicado 2017

A Quantitative Increase in Regulatory T Cells Controls Development of Vitiligo

por Chatterjee, Shilpak, Eby, Jonathan, Al-Khami, Amir A., Soloshchenko, Myroslawa, Kang, Hee-Kap, Kaur, Navtej, Naga, Osama, Murali, Anuradha, Nishimura, Michael I., Le Poole, I. Caroline, Mehrotra, Shikhar
Publicado 2013

Inhibition of fatty acid oxidation modulates immunosuppressive functions of myeloid-derived suppressor cells and enhances cancer therapies

por Al-Khami, Amir A, Hossain, Fokhrul, Wyczechowska, Dorota, Hernandez, Claudia, Zheng, Liqin, Reiss, Krzystoff, Del Valle, Luis, Trillo-Tinoco, Jimena, Maj, Tomasz, Zou, Weiping, Rodriguez, Paulo C, Ochoa, Augusto C
Publicado 2015

PARP-1 Is Critical for Recruitment of Dendritic Cells to the Lung in a Mouse Model of Asthma but Dispensable for Their Differentiation and Function

por Echeverri Tirado, Laura C., Ghonim, Mohamed A., Wang, Jeffrey, Al-Khami, Amir A., Wyczechowska, Dorota, Luu, Hanh H., Kim, Hogyoung, Sanchez-Pino, Maria Dulfary, Yélamos, José, Yassin, Lina M., Boulares, A. Hamid
Publicado 2019

Targeting PARP-1 with metronomic therapy modulates MDSC suppressive function and enhances anti-PD-1 immunotherapy in colon cancer

por Ghonim, Mohamed A, Ibba, Salome V, Tarhuni, Abdelmetalab F, Errami, Youssef, Luu, Hanh H, Dean, Matthew J, El-Bahrawy, Ali H, Wyczechowska, Dorota, Benslimane, Ilyes A, Del Valle, Luis, Al-Khami, Amir A, Ochoa, Augusto C, Boulares, A Hamid
Publicado 2021

PARP inhibition by olaparib or gene knockout blocks asthma-like manifestation in mice by modulating CD4(+) T cell function

por Ghonim, Mohamed A, Pyakurel, Kusma, Ibba, Salome V, Al-Khami, Amir A, Wang, Jeffrey, Rodriguez, Paulo, Rady, Hamada F, El-Bahrawy, Ali H, Lammi, Matthew R, Mansy, Moselhy S, Al-Ghareeb, Kamel, Ramsay, Alistair, Ochoa, Augusto, Naura, Amarjit S, Boulares, A Hamid
Publicado 2015

Combinatorial immunotherapy induces tumor-infiltrating CD8(+) T cells with distinct functional, migratory, and stem-like properties

por Van Braeckel-Budimir, Natalija, Dolina, Joseph Samuel, Wei, Jie, Wang, Xiao, Chen, Shih-Hsun, Santiago, Pamela, Tu, Guanghuan, Micci, Luca, Al-Khami, Amir A, Pfister, Sophia, Ram, Sripad, Sundar, Purnima, Thomas, Graham, Long, Hua, Yang, Wenjing, Potluri, Shobha, Salek-Ardakani, Shahram
Publicado 2021

PARP is activated in human asthma and its inhibition by olaparib blocks house dust mite-induced disease in mice

por Ghonim, Mohamed A., Pyakurel, Kusma, Ibba, Salome V., Wang, Jeffrey, Rodriguez, Paulo, Al-Khami, Amir A., Lammi, Matthew R., Kim, Hogyoung, Zea, Arnold H., Davis, Christian, Okpechi, Samuel, Wyczechowska, Dorota, Al-Ghareeb, Kamel, Mansy, Moselhy S., Ochoa, Augusto, Naura, Amarjit S., Boulares, A. Hamid
Publicado 2015

Increased inflammatory low-density neutrophils in severe obesity and effect of bariatric surgery: Results from case-control and prospective cohort studies

por Sanchez-Pino, Maria Dulfary, Richardson, William S., Zabaleta, Jovanny, Puttalingaiah, Ramesh Thylur, Chapple, Andrew G., Liu, Jiao, Kim, Yonghyan, Ponder, Michelle, DeArmitt, Randi, Baiamonte, Lyndsey Buckner, Wyczechowska, Dorota, Zheng, Liqin, Al-Khami, Amir A., Garai, Jone, Martini, Rachel, Davis, Melissa, Gorham, Jessica Koller, Wooldridge, James B., Rodriguez, Paulo C., Miele, Lucio, Ochoa, Augusto C.
Publicado 2022

Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity

por Chakraborty, Paramita, Vaena, Silvia G., Thyagarajan, Krishnamurthy, Chatterjee, Shilpak, Al-Khami, Amir, Selvam, Shanmugam Panneer, Nguyen, Hung, Kang, Inhong, Wyatt, Megan W., Baliga, Uday, Hedley, Zachariah, Ngang, Rose N., Guo, Beichu, Beeson, Gyda C., Husain, Shahid, Paulos, Chrystal M., Beeson, Craig C., Zilliox, Michael J., Hill, Elizabeth G., Mehrotra, Meenal, Yu, Xue-Zhong, Ogretmen, Besim, Mehrotra, Shikhar
Publicado 2019