Design, Synthesis and Pharmacological Evaluation of 2-(3-BenzoyI-4-Hydroxy-1,1-Dioxido-2H-Benzo[e][1,2]thiazin-2-yI)-N-(2-Bromophenyl) Acetamide as Antidiabetic Agent

por Rashid, Fatima, Ahmad, Matloob, Ashfaq, Usman Ali, Al-Mutairi, Aamal A, Al-Hussain, Sami A
Publicado 2022

Synthesis and Antimicrobial, Anticancer and Anti-Oxidant Activities of Novel 2,3-Dihydropyrido[2,3-d]pyrimidine-4-one and Pyrrolo[2,1-b][1,3]benzothiazole Derivatives via Microwave...

por Al-Mutairi, Aamal A., Hafez, Hend N., El-Gazzar, Abdel-Rhaman B. A., Mohamed, Marwa Y. A.
Publicado 2022

Synthesis and Structure Insights of Two Novel Broad-Spectrum Antibacterial Candidates Based on (E)-N′-[(Heteroaryl)methylene]adamantane-1-carbohydrazides

por Al-Wahaibi, Lamya H., Alvarez, Natalia, Blacque, Olivier, Veiga, Nicolás, Al-Mutairi, Aamal A., El-Emam, Ali A.
Publicado 2020

Mechanistic Analysis of Chemically Diverse Bromodomain-4 Inhibitors Using Balanced QSAR Analysis and Supported by X-ray Resolved Crystal Structures

por Zaki, Magdi E. A., Al-Hussain, Sami A., Al-Mutairi, Aamal A., Masand, Vijay H., Samad, Abdul, Jawarkar, Rahul D.
Publicado 2022

Syntheses and crystal structures of two adamantyl-substituted 1,2,4-triazole-5-thione N-Mannich bases

por Al-Alshaikh, Monirah A., Al-Mutairi, Aamal A., Ghabbour, Hazem A., El-Emam, Ali A., Abdelbaky, Mohammed S. M., Garcia-Granda, Santiago
Publicado 2017

Crystallographic and Theoretical Exploration of Weak Hydrogen Bonds in Arylmethyl N′-(adamantan-1-yl)piperidine-1-carbothioimidates and Molecular Docking Analysis

por Al-Mutairi, Aamal A., Alagappan, Kowsalya, Blacque, Olivier, Al-Alshaikh, Monirah A., El-Emam, Ali A., Percino, M. Judith, Thamotharan, Subbiah
Publicado 2021

Synthesis, Antimicrobial, and Anti-Proliferative Activities of Novel 4-(Adamantan-1-yl)-1-arylidene-3-thiosemicarbazides, 4-Arylmethyl N′-(Adamantan-1-yl)piperidine-1-carbothioimid...

por Al-Mutairi, Aamal A., Al-Alshaikh, Monirah A., Al-Omary, Fatmah A. M., Hassan, Hanan M., El-Mahdy, Areej M., El-Emam, Ali A.
Publicado 2019

Pharmacophore Synergism in Diverse Scaffold Clinches in Aurora Kinase B

por Masand, Vijay H., Al-Hussain, Sami A., Rathore, Mithilesh M., Thakur, Sumer D., Akasapu, Siddhartha, Samad, Abdul, Al-Mutairi, Aamal A., Zaki, Magdi E. A.
Publicado 2022

In-silico studies to recognize repurposing therapeutics toward arginase-I inhibitors as a potential onco-immunomodulators

por Zaki, Magdi E. A., Al-Hussain, Sami A., Al-Mutairi, Aamal A., Samad, Abdul, Ghosh, Arabinda, Chaudhari, Somdatta, Khatale, Pravin N., Ajmire, Prashant, Jawarkar, Rahul D.
Publicado 2023

QSAR Evaluations to Unravel the Structural Features in Lysine-Specific Histone Demethylase 1A Inhibitors for Novel Anticancer Lead Development Supported by Molecular Docking, MD Si...

por Jawarkar, Rahul D., Bakal, Ravindra L., Mukherjee, Nobendu, Ghosh, Arabinda, Zaki, Magdi E. A., AL-Hussain, Sami A., Al-Mutairi, Aamal A., Samad, Abdul, Gandhi, Ajaykumar, Masand, Vijay H.
Publicado 2022

Quantitative analysis of hydrogen and chalcogen bonds in two pyrimidine-5-carbonitrile derivatives, potential DHFR inhibitors: an integrated crystallographic and theoretical study

por Al-Wahaibi, Lamya H., Chakraborty, Kushumita, Al-Shaalan, Nora H., Syed Majeed, Mohamed Yehya Annavi, Blacque, Olivier, Al-Mutairi, Aamal A., El-Emam, Ali A., Percino, M. Judith, Thamotharan, Subbiah
Publicado 2020

QSAR, Molecular Docking, MD Simulation and MMGBSA Calculations Approaches to Recognize Concealed Pharmacophoric Features Requisite for the Optimization of ALK Tyrosine Kinase Inhib...

por Jawarkar, Rahul D., Sharma, Praveen, Jain, Neetesh, Gandhi, Ajaykumar, Mukerjee, Nobendu, Al-Mutairi, Aamal A., Zaki, Magdi E. A., Al-Hussain, Sami A., Samad, Abdul, Masand, Vijay H., Ghosh, Arabinda, Bakal, Ravindra L.
Publicado 2022

Scrophularia peyronii Post. from Jordan: Chemical Composition of Essential Oil and Phytochemical Profiling of Crude Extracts and Their In Vitro Antioxidant Activity

por Al-Dalahmeh, Yousef, Almahmoud, Sondos Abdullah J., Al-Bataineh, Nezar, Alghzawi, Taqwa A., Alhamzani, Abdulrahman G., Al-Mutairi, Aamal A., Al-Jaber, Hala I., Abu Orabi, Sultan T., Bataineh, Tareq T., Al-Sheraideh, Mohammed S., Al-Qudah, Mahmoud A.
Publicado 2023