Generation of the First Structure-Based Pharmacophore Model Containing a Selective “Zinc Binding Group” Feature to Identify Potential Glyoxalase-1 Inhibitors

por Al-Balas, Qosay, Hassan, Mohammad, Al-Oudat, Buthina, Alzoubi, Hassan, Mhaidat, Nizar, Almaaytah, Ammar
Publicado 2012

Design, Synthesis and Biological Evaluation of 1,4-Benzenesulfonamide Derivatives as Glyoxalase I Inhibitors

por Audat, Suaad Abdallah, Al-Balas, Qosay Ali, Al-Oudat, Buthina Abdallah, Athamneh, Mo’ad Jamil, Bryant-Friedrich, Amanda
Publicado 2022

Identification of Human Leukotriene A4 Hydrolase Inhibitors Using Structure-Based Pharmacophore Modeling and Molecular Docking

por Audat, Suaad A., Al-Shar’i, Nizar A., Al-Oudat, Buthina A., Bryant-Friedrich, Amanda, Bedi, Mel F., Zayed, Aref L., Al-Balas, Qosay A.
Publicado 2020

Design, synthesis, and biologic evaluation of novel chrysin derivatives as cytotoxic agents and caspase-3/7 activators

por Al-Oudat, Buthina Abdallah, Alqudah, Mohammad Ali, Audat, Suaad Abdallah, Al-Balas, Qosay Ali, El-Elimat, Tamam, Hassan, Mohammad Abdelhafeez, Frhat, Islam Nawaf, Azaizeh, Marwah Mohammad
Publicado 2019

Novel Chrysin-De-Allyl PAC-1 Hybrid Analogues as Anticancer Compounds: Design, Synthesis, and Biological Evaluation

por Al-Oudat, Buthina A., Ramapuram, Hariteja, Malla, Saloni, Audat, Suaad A., Hussein, Noor, Len, Jenna M., Kumari, Shikha, Bedi, Mel F., Ashby, Charles R., Tiwari, Amit K.
Publicado 2020