Synthesis and In Vitro Anticancer Activity of Novel 4-Aryl-3-(4-methoxyphenyl)-1-phenyl-1H-pyrazolo[3,4-b]pyridines Arrest Cell Cycle and Induce Cell Apoptosis by Inhibiting CDK2 a...

por Almansour, Basma S., Binjubair, Faizah A., Abdel-Aziz, Alaa A.-M., Al-Rashood, Sara T.
Publicado 2023

Identification of a New Potential SARS-COV-2 RNA-Dependent RNA Polymerase Inhibitor via Combining Fragment-Based Drug Design, Docking, Molecular Dynamics, and MM-PBSA Calculations

por El Hassab, Mahmoud A., Shoun, Aly A., Al-Rashood, Sara T., Al-Warhi, Tarfah, Eldehna, Wagdy M.
Publicado 2020

Marine-Inspired Bis-indoles Possessing Antiproliferative Activity against Breast Cancer; Design, Synthesis, and Biological Evaluation

por Eldehna, Wagdy M., Hassan, Ghada S., Al-Rashood, Sara T., Alkahtani, Hamad M., A. Almehizia, Abdulrahman, Al-Ansary, Ghada H.
Publicado 2020

Novel oxindole/benzofuran hybrids as potential dual CDK2/GSK-3β inhibitors targeting breast cancer: design, synthesis, biological evaluation, and in silico studies

por Eldehna, Wagdy M., Al-Rashood, Sara T., Al-Warhi, Tarfah, Eskandrani, Razan O., Alharbi, Amal, El Kerdawy, Ahmed M.
Publicado 2020

In silico identification of novel SARS-COV-2 2′-O-methyltransferase (nsp16) inhibitors: structure-based virtual screening, molecular dynamics simulation and MM-PBSA approaches

por El Hassab, Mahmoud A., Ibrahim, Tamer M., Al-Rashood, Sara T., Alharbi, Amal, Eskandrani, Razan O., Eldehna, Wagdy M.
Publicado 2021

GC/MS Analysis of Essential Oil and Enzyme Inhibitory Activities of Syzygium cumini (Pamposia) Grown in Egypt: Chemical Characterization and Molecular Docking Studies

por El-Nashar, Heba A. S., Eldehna, Wagdy M., Al-Rashood, Sara T., Alharbi, Amal, Eskandrani, Razan O., Aly, Shaza H.
Publicado 2021

New Thiazolyl-Pyrazoline Derivatives as Potential Dual EGFR/HER2 Inhibitors: Design, Synthesis, Anticancer Activity Evaluation and In Silico Study

por Fakhry, Mariam M., Mattar, Amr A., Alsulaimany, Marwa, Al-Olayan, Ebtesam M., Al-Rashood, Sara T., Abdel-Aziz, Hatem A.
Publicado 2023

Phytonutrients, Colorant Pigments, Phytochemicals, and Antioxidant Potential of Orphan Leafy Amaranthus Species

por Sarker, Umakanta, Rabbani, Md. Golam, Oba, Shinya, Eldehna, Wagdy M., Al-Rashood, Sara T., Mostafa, Nada M., Eldahshan, Omayma A.
Publicado 2022

Fenticonazole nitrate loaded trans-novasomes for effective management of tinea corporis: design characterization, in silico study, and exploratory clinical appraisal

por Albash, Rofida, Ragaie, Maha H., Hassab, Mahmoud A. El, El-Haggar, Radwan, Eldehna, Wagdy M., Al-Rashood, Sara T., Mosallam, Shaimaa
Publicado 2022

Novel 3-(6-methylpyridin-2-yl)coumarin-based chalcones as selective inhibitors of cancer-related carbonic anhydrases IX and XII endowed with anti-proliferative activity

por Tawfik, Haytham O., Shaldam, Moataz A., Nocentini, Alessio, Salem, Rofaida, Almahli, Hadia, Al-Rashood, Sara T., Supuran, Claudiu T., Eldehna, Wagdy M.
Publicado 2022

The Antioxidant and Enzyme Inhibitory Potential of n-Hexane-Extracted Oils Obtained from Three Egyptian Cultivars of the Golden Dewdrop Duranta erecta Linn. Supported by Their GC-M...

por Fayez, Shaimaa, Zengin, Gokhan, Al-Rashood, Sara T., El Hassab, Mahmoud A., Eldehna, Wagdy M., Dall’Acqua, Stefano, Eldahshan, Omayma A.
Publicado 2022

Validated Microwell-Based Spectrofluorimetric Method for Quantification of Ravidasvir (New Anti-Chronic Hepatitis C Virus-GT4) in Rat Plasma and Its Application to Pharmacokinetic...

por Hefnawy, Mohamed, Al-Shehri, Mona, Al-Rashood, Sara, Hammad, Sherif, Alanazi, Mohammed, Alsaif, Nawaf, Mohammed, Mostafa, Obaidullah, Ahmad, El-Gendy, Manal
Publicado 2020

GC/MS Profiling, Anti-Collagenase, Anti-Elastase, Anti-Tyrosinase and Anti-Hyaluronidase Activities of a Stenocarpus sinuatus Leaves Extract

por Younis, Mai M., Ayoub, Iriny M., Mostafa, Nada M., El Hassab, Mahmoud A., Eldehna, Wagdy M., Al-Rashood, Sara T., Eldahshan, Omayma A.
Publicado 2022

Antitumor properties of certain spirooxindoles towards hepatocellular carcinoma endowed with antioxidant activity

por Al-Rashood, Sara T., Hamed, Ahmed R., Hassan, Ghada S., Alkahtani, Hamad M., Almehizia, Abdulrahman A., Alharbi, Amal, Al-Sanea, Mohammad M., Eldehna, Wagdy M.
Publicado 2020

GC/MS analysis and potential synergistic effect of mandarin and marjoram oils on Helicobacter pylori

por Elkousy, Rawah H., Mostafa, Nada M., Abd-alkhalek, Ahmed M., El Hassab, Mahmoud A., Al-Rashood, Sara T., Eldehna, Wagdy M., Eldahshan, Omayma A.
Publicado 2022

In Silico Docking, Resistance Modulation and Biofilm Gene Expression in Multidrug-Resistant Acinetobacter baumannii via Cinnamic and Gallic Acids

por Abdelaziz, Neveen A., Elkhatib, Walid F., Sherif, Mahmoud M., Abourehab, Mohammed A. S., Al-Rashood, Sara T., Eldehna, Wagdy M., Mostafa, Nada M., Elleboudy, Nooran S.
Publicado 2022

Synthesis, Biological Evaluation and 2D-QSAR Study of Halophenyl Bis-Hydrazones as Antimicrobial and Antitubercular Agents

por Abdel-Aziz, Hatem A., Eldehna, Wagdy M., Fares, Mohamed, Al-Rashood, Sara T. A., Al-Rashood, Khalid A., Abdel-Aziz, Marwa M., Soliman, Dalia H.
Publicado 2015

Synthesis and in vitro anticancer activity of certain novel 1-(2-methyl-6-arylpyridin-3-yl)-3-phenylureas as apoptosis-inducing agents

por Eldehna, Wagdy M., Hassan, Ghada S., Al-Rashood, Sara T., Al-Warhi, Tarfah, Altyar, Ahmed E., Alkahtani, Hamad M., Almehizia, Abdulrahman A., Abdel-Aziz, Hatem A.
Publicado 2019

In silico identification of potential SARS COV-2 2′-O-methyltransferase inhibitor: fragment-based screening approach and MM-PBSA calculations

por El Hassab, Mahmoud A., Ibrahim, Tamer M., Shoun, Aly A., Al-Rashood, Sara T., Alkahtani, Hamad M., Alharbi, Amal, Eskandrani, Razan O., Eldehna, Wagdy M.
Publicado 2021

Chemical Constituents, Antioxidant, and Enzyme Inhibitory Activities Supported by In-Silico Study of n-Hexane Extract and Essential Oil of Guava Leaves

por Aly, Shaza H., Eldahshan, Omayma A., Al-Rashood, Sara T., Binjubair, Faizah A., El Hassab, Mahmoud A., Eldehna, Wagdy M., Dall’Acqua, Stefano, Zengin, Gokhan
Publicado 2022