LC-MS/MS Estimation of the Anti-Cancer Agent Tandutinib Levels in Human Liver Microsomes: Metabolic Stability Evaluation Assay

por Attwa, Mohamed W, Abdelhameed, Ali S, Al-Shakliah, Nasser S, Kadi, Adnan A
Publicado 2020

A Validated LC–MS/MS Assay for the Simultaneous Quantification of the FDA-Approved Anticancer Mixture (Encorafenib and Binimetinib): Metabolic Stability Estimation

por Attwa, Mohamed W., Darwish, Hany W., Al-Shakliah, Nasser S., Kadi, Adnan A.
Publicado 2021

Identification and characterization of in silico, in vivo, in vitro, and reactive metabolites of infigratinib using LC-ITMS: bioactivation pathway elucidation and in silico toxicit...

por Al-Shakliah, Nasser S., Attwa, Mohamed W., Kadi, Adnan A., AlRabiah, Haitham
Publicado 2020

Development and Validation of an HPLC-UV Detection Assay for the Determination of Clonidine in Mouse Plasma and Its Application to a Pharmacokinetic Study

por AlRabiah, Haitham, Attia, Sabry M., Al-Shakliah, Nasser S., Mostafa, Gamal A. E.
Publicado 2020

In Vitro Identification of Potential Metabolites of Plinabulin (NPI 2358) in Hepatic Preparations Using Liquid Chromatography–Ion Trap Mass Spectrometry

por Al-Shakliah, Nasser S., Kadi, Adnan A., Al-Salahi, Rashad, Rahman, A. F. M. Motiur
Publicado 2022

Identification and characterization of in vivo, in vitro and reactive metabolites of vandetanib using LC–ESI–MS/MS

por Attwa, Mohamed W., Kadi, Adnan A., Darwish, Hany W., Amer, Sawsan M., Al-shakliah, Nasser S.
Publicado 2018

Profiling of in vivo, in vitro and reactive zorifertinib metabolites using liquid chromatography ion trap mass spectrometry

por Al-Shakliah, Nasser S., Kadi, Adnan A., Aljohar, Haya I., AlRabiah, Haitham, Attwa, Mohamed W.
Publicado 2022

Experimental and computational evaluation of kolliphor RH 40 as a new fluorescence enhancer in development of a micellar-based spectrofluorimetric method for determination of lapat...

por Darwish, Hany W., Bakheit, Ahmed H., Al-shakliah, Nasser S., Rahman, A. F. M. Motiur, Darwish, Ibrahim A.
Publicado 2020

A New Validated HPLC-MS/MS Method for Quantification and Pharmacokinetic Evaluation of Dovitinib, a Multi-Kinase Inhibitor, in Mouse Plasma

por AlRabiah, Haitham, Kadi, Adnan A, Aljohar, Haya I, Attwa, Mohamed W, Al-Shakliah, Nasser S, Attia, Sabry M, Mostafa, Gamal AE
Publicado 2020