Crystal structures and Hirshfeld surface analysis of 2-(adamantan-1-yl)-5-(4-fluoro­phen­yl)-1,3,4-oxa­diazole and 2-(adamantan-1-yl)-5-(4-chloro­phen­yl)-1,3,4-oxa­diazole

por Al-Wahaibi, Lamya H., Alsfouk, Aisha, El-Emam, Ali A., Blacque, Olivier
Publicado 2019

Suppression of Cisplatin-Induced Hepatic Injury in Rats Through Alarmin High-Mobility Group Box-1 Pathway by Ganoderma lucidum: Theoretical and Experimental Study

por Hassan, Hanan M, Al-Wahaibi, Lamya H, Elmorsy, Mohammed A, Mahran, Yasmen F
Publicado 2020

One-Pot Synthesis of 1-Thia-4-azaspiro[4.4/5]alkan-3-ones via Schiff Base: Design, Synthesis, and Apoptotic Antiproliferative Properties of Dual EGFR/BRAF(V600E) Inhibitors

por Al-Wahaibi, Lamya H., El-Sheref, Essmat M., Hammouda, Mohamed M., Youssif, Bahaa G. M.
Publicado 2023

Design, Synthesis, and Biological Evaluation of Indole-2-carboxamides as Potential Multi-Target Antiproliferative Agents

por Al-Wahaibi, Lamya H., Mohammed, Anber F., Abdelrahman, Mostafa H., Trembleau, Laurent, Youssif, Bahaa G. M.
Publicado 2023

Crystal structure, Hirshfeld surface analysis and DFT studies of 5-(adamantan-1-yl)-3-[(4-chlorobenzyl)sulfanyl]-4-methyl-4H-1,2,4-triazole, a potential 11β-HSD1 inhibitor

por Al-Wahaibi, Lamya H., Joubert, Jacques, Blacque, Olivier, Al-Shaalan, Nora H., El-Emam, Ali A.
Publicado 2019

Design, Synthesis, and Antiproliferative Activity of New 5-Chloro-indole-2-carboxylate and Pyrrolo[3,4-b]indol-3-one Derivatives as Potent Inhibitors of EGFR(T790M)/BRAF(V600E) Pat...

por Al-Wahaibi, Lamya H., Mohammed, Anber F., Abdelrahman, Mostafa H., Trembleau, Laurent, Youssif, Bahaa G. M.
Publicado 2023

1,3,4-Oxadiazole N-Mannich Bases: Synthesis, Antimicrobial, and Anti-Proliferative Activities

por Al-Wahaibi, Lamya H., Mohamed, Ahmed A. B., Tawfik, Samar S., Hassan, Hanan M., El-Emam, Ali A.
Publicado 2021

Novel piperine-carboximidamide hybrids: design, synthesis, and antiproliferative activity via a multi-targeted inhibitory pathway

por Al-Wahaibi, Lamya H., Mahmoud, Mohamed A., Mostafa, Yaser A., Raslan, Ali E., Youssif, Bahaa G. M.
Publicado 2022

Adamantane-Isothiourea Hybrid Derivatives: Synthesis, Characterization, In Vitro Antimicrobial, and In Vivo Hypoglycemic Activities

por Al-Wahaibi, Lamya H., Hassan, Hanan M., Abo-Kamar, Amal M., Ghabbour, Hazem A., El-Emam, Ali A.
Publicado 2017

Synthesis and Structure Insights of Two Novel Broad-Spectrum Antibacterial Candidates Based on (E)-N′-[(Heteroaryl)methylene]adamantane-1-carbohydrazides

por Al-Wahaibi, Lamya H., Alvarez, Natalia, Blacque, Olivier, Veiga, Nicolás, Al-Mutairi, Aamal A., El-Emam, Ali A.
Publicado 2020

Design, Synthesis, Biological Evaluation, and Computational Studies of Novel Tri-Aryl Imidazole-Benzene Sulfonamide Hybrids as Promising Selective Carbonic Anhydrase IX and XII Inh...

por Al-Wahaibi, Lamya H., Youssif, Bahaa G. M., Taher, Ehab S., Abdelazeem, Ahmed H., Abdelhamid, Antar A., Marzouk, Adel A.
Publicado 2021

Synthesis and Biological Evaluation of Indole-2-Carboxamides with Potent Apoptotic Antiproliferative Activity as EGFR/CDK2 Dual Inhibitors

por Al-Wahaibi, Lamya H., Mostafa, Yaser A., Abdelrahman, Mostafa H., El-Bahrawy, Ali H., Trembleau, Laurent, Youssif, Bahaa G. M.
Publicado 2022

Design, Synthesis, and Antibacterial Screening of Some Novel Heteroaryl-Based Ciprofloxacin Derivatives as DNA Gyrase and Topoisomerase IV Inhibitors

por Al-Wahaibi, Lamya H., Amer, Amer A., Marzouk, Adel A., Gomaa, Hesham A. M., Youssif, Bahaa G. M., Abdelhamid, Antar A.
Publicado 2021

Design, Synthesis, Antiproliferative Actions, and DFT Studies of New Bis–Pyrazoline Derivatives as Dual EGFR/BRAF(V600E) Inhibitors

por Al-Wahaibi, Lamya H., Abou-Zied, Hesham A., Beshr, Eman A. M., Youssif, Bahaa G. M., Hayallah, Alaa M., Abdel-Aziz, Mohamed
Publicado 2023

A combined crystallographic and theoretical investigation of noncovalent interactions in 1,3,4-oxadiazole-2-thione-N-Mannich derivatives: in vitro bioactivity and molecular docking

por Al-Wahaibi, Lamya H., Alagappan, Kowsalya, Gomila, Rosa M., Blacque, Olivier, Frontera, Antonio, Percino, M. Judith, El-Emam, Ali A., Thamotharan, Subbiah
Publicado 2023

Design, synthesis, apoptotic, and antiproliferative effects of 5-chloro-3- (2-methoxyvinyl)-indole-2-carboxamides and pyrido[3,4-b]indol-1-ones as potent EGFR(WT/)EGFR(T790M) inhib...

por Al-Wahaibi, Lamya H., Mohammed, Anber F., Abdel Rahman, Fatema El-Zahraa S., Abdelrahman, Mostafa H., Gu, Xuyuan, Trembleau, Laurent, Youssif, Bahaa G. M.
Publicado 2023

Structural Insights of Three 2,4-Disubstituted Dihydropyrimidine-5-carbonitriles as Potential Dihydrofolate Reductase Inhibitors

por Al-Wahaibi, Lamya H., Shaik, Althaf, Elmorsy, Mohammed A., Abdelbaky, Mohammed S. M., Garcia-Granda, Santiago, Thamotharan, Subbiah, Thiruvenkatam, Vijay, El-Emam, Ali A.
Publicado 2021

Structural and Energetic Properties of Weak Noncovalent Interactions in Two Closely Related 3,6-Disubstituted-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole Derivatives: In Vitro Cycloox...

por Al-Wahaibi, Lamya H., Karthikeyan, Sekar, Blacque, Olivier, El-Masry, Amal A., Hassan, Hanan M., Percino, M. Judith, El-Emam, Ali A., Thamotharan, Subbiah
Publicado 2022

X-ray Structures and Computational Studies of Two Bioactive 2-(Adamantane-1-carbonyl)-N-substituted Hydrazine-1-carbothioamides

por Al-Wahaibi, Lamya H., Alagappan, Kowsalya, Blacque, Olivier, Mohamed, Ahmed A. B., Hassan, Hanan M., Percino, María Judith, El-Emam, Ali A., Thamotharan, Subbiah
Publicado 2022

Metabolites Profiling and In Vitro Biological Characterization of Different Fractions of Cliona sp. Marine Sponge from the Red Sea Egypt

por Hassan, Wafaa H. B., El Sayed, Zeinab I., Al-Wahaibi, Lamya H., Abdel-Aal, Mahmoud M., Abdel-Mageed, Wael M., Abdelsalam, Eman, Abdelaziz, Sahar
Publicado 2023