Design, synthesis, docking, and anticancer evaluations of new thiazolo[3,2-a] pyrimidines as topoisomerase II inhibitors

por El-Zoghbi, Mona S., El-Sebaey, Samiha A., AL-Ghulikah, Hanan A., Sobh, Eman A.
Publicado 2023

New Pyrimidine-5-Carbonitriles as COX-2 Inhibitors: Design, Synthesis, Anticancer Screening, Molecular Docking, and In Silico ADME Profile Studies

por AL-Ghulikah, Hanan A., El-Sebaey, Samiha A., Bass, Amr K. A., El-Zoghbi, Mona S.
Publicado 2022

Novel Aminopyrimidine-2,4-diones, 2-Thiopyrimidine-4-ones, and 6-Arylpteridines as Dual-Target Inhibitors of BRD4/PLK1: Design, Synthesis, Cytotoxicity, and Computational Studies

por El-Kalyoubi, Samar, El-Sebaey, Samiha A., Elfeky, Sherin M., AL-Ghulikah, Hanan A., El-Zoghbi, Mona S.
Publicado 2023

Synthesis, DFT calculations, and anti-proliferative evaluation of pyrimidine and selenadiazolopyrimidine derivatives as dual Topoisomerase II and HSP90 inhibitors

por El-Kalyoubi, Samar, El-Sebaey, Samiha A., Rashad, A. M., AL-Ghulikah, Hanan A., Ghorab, Mostafa M., Elfeky, Sherin M.
Publicado 2023

(E)-N-(3-(1-(2-(4-(2,2,2-Trifluoroacetamido)benzoyl)hydrazono)ethyl)phenyl)nicotinamide: A Novel Pyridine Derivative for Inhibiting Vascular Endothelial Growth Factor Receptor-2: S...

por Yousef, Reda G., Elkady, Hazem, Elkaeed, Eslam B., Gobaara, Ibraheem M. M., Al-ghulikah, Hanan A., Husein, Dalal Z., Ibrahim, Ibrahim M., Metwaly, Ahmed M., Eissa, Ibrahim H.
Publicado 2022

Molecular iodine-promoted oxidative cyclization for the synthesis of 1,3,4-thiadiazole-fused- [1,2,4]-thiadiazole incorporating 1,4-benzodioxine moiety as potent inhibitors of α-am...

por Hussain, Rafaqat, Shah, Mazloom, Iqbal, Shahid, Rehman, Wajid, Khan, Shoaib, Rasheed, Liaqat, Naz, Haseena, Al-ghulikah, Hanan A., Elkaeed, Eslam B., Pashameah, Rami Adel, Alzahrani, Eman, Farouk, Abd-ElAziem
Publicado 2022

Synthesis of Novel 2,3-Dihydro-1,5-Benzothiazepines as α-Glucosidase Inhibitors: In Vitro, In Vivo, Kinetic, SAR, Molecular Docking, and QSAR Studies

por Mehmood, Rabia, Mughal, Ehsan Ullah, Elkaeed, Eslam B., Obaid, Rami J., Nazir, Yasir, Al-Ghulikah, Hanan A., Naeem, Nafeesa, Al-Rooqi, Munirah M., Ahmed, Saleh A., Shah, Syed Wadood Ali, Sadiq, Amina
Publicado 2022

New Triazinoindole Bearing Benzimidazole/Benzoxazole Hybrids Analogs as Potent Inhibitors of Urease: Synthesis, In Vitro Analysis and Molecular Docking Studies

por Mumtaz, Sundas, Iqbal, Shahid, Shah, Mazloom, Hussain, Rafaqat, Rahim, Fazal, Rehman, Wajid, Khan, Shoaib, Abid, Obaid-ur-Rahman, Rasheed, Liaqat, Dera, Ayed A., Al-ghulikah, Hanan A., Kehili, Sana, Elkaeed, Eslam B., Alrbyawi, Hamad, Alahmdi, Mohammed Issa
Publicado 2022