Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines

por Scepanovic, Petar, Alanio, Cécile, Hammer, Christian, Hodel, Flavia, Bergstedt, Jacob, Patin, Etienne, Thorball, Christian W., Chaturvedi, Nimisha, Charbit, Bruno, Abel, Laurent, Quintana-Murci, Lluis, Duffy, Darragh, Albert, Matthew L., Fellay, Jacques
Publicado 2018

A comprehensive assessment of demographic, environmental, and host genetic associations with gut microbiome diversity in healthy individuals

por Scepanovic, Petar, Hodel, Flavia, Mondot, Stanislas, Partula, Valentin, Byrd, Allyson, Hammer, Christian, Alanio, Cécile, Bergstedt, Jacob, Patin, Etienne, Touvier, Mathilde, Lantz, Olivier, Albert, Matthew L., Duffy, Darragh, Quintana-Murci, Lluis, Fellay, Jacques
Publicado 2019

Vaccine-induced ICOS(+)CD38(+) circulating Tfh are sensitive biosensors of age-related changes in inflammatory pathways

por Herati, Ramin Sedaghat, Silva, Luisa Victoria, Vella, Laura A., Muselman, Alexander, Alanio, Cecile, Bengsch, Bertram, Kurupati, Raj K., Kannan, Senthil, Manne, Sasikanth, Kossenkov, Andrew V., Canaday, David H., Doyle, Susan A., Ertl, Hildegund C.J., Schmader, Kenneth E., Wherry, E. John
Publicado 2021

Primary immune responses are negatively impacted by persistent herpesvirus infections in older people: results from an observational study on healthy subjects and a vaccination tri...

por Nicoli, Francesco, Clave, Emmanuel, Wanke, Kerstin, von Braun, Amrei, Bondet, Vincent, Alanio, Cécile, Douay, Corinne, Baque, Margaux, Lependu, Claire, Marconi, Peggy, Stiasny, Karin, Heinz, Franz X., Muetsch, Margot, Duffy, Darragh, Boddaert, Jacques, Sauce, Delphine, Toubert, Antoine, Karrer, Urs, Appay, Victor
Publicado 2022

Cytomegalovirus Latent Infection is Associated with an Increased Risk of COVID-19-Related Hospitalization

por Alanio, Cécile, Verma, Anurag, Mathew, Divij, Gouma, Sigrid, Liang, Guanxiang, Dunn, Thomas, Oldridge, Derek A, Weaver, JoEllen, Kuri-Cervantes, Leticia, Pampena, M Betina, Betts, Michael R, Collman, Ronald G, Bushman, Frederic D, Meyer, Nuala J, Hensley, Scott E, Rader, Daniel, Wherry, E John
Publicado 2022

Bystander hyperactivation of preimmune CD8(+) T cells in chronic HCV patients

por Alanio, Cécile, Nicoli, Francesco, Sultanik, Philippe, Flecken, Tobias, Perot, Brieuc, Duffy, Darragh, Bianchi, Elisabetta, Lim, Annick, Clave, Emmanuel, van Buuren, Marit M, Schnuriger, Aurélie, Johnsson, Kerstin, Boussier, Jeremy, Garbarg-Chenon, Antoine, Bousquet, Laurence, Mottez, Estelle, Schumacher, Ton N, Toubert, Antoine, Appay, Victor, Heshmati, Farhad, Thimme, Robert, Pol, Stanislas, Mallet, Vincent, Albert, Matthew L
Publicado 2015

Neoadjuvant Selicrelumab, an Agonist CD40 Antibody, Induces Changes in the Tumor Microenvironment in Patients with Resectable Pancreatic Cancer

por Byrne, Katelyn T., Betts, Courtney B., Mick, Rosemarie, Sivagnanam, Shamilene, Bajor, David L., Laheru, Daniel A., Chiorean, E. Gabriela, O'Hara, Mark H., Liudahl, Shannon M., Newcomb, Craig, Alanio, Cécile, Ferreira, Ana P., Park, Byung S., Ohtani, Takuya, Huffman, Austin P., Väyrynen, Sara A., Dias Costa, Andressa, Kaiser, Judith C., Lacroix, Andreanne M., Redlinger, Colleen, Stern, Martin, Nowak, Jonathan A., Wherry, E. John, Cheever, Martin A., Wolpin, Brian M., Furth, Emma E., Jaffee, Elizabeth M., Coussens, Lisa M., Vonderheide, Robert H.
Publicado 2021

Seasonal human coronavirus antibodies are boosted upon SARS-CoV-2 infection but not associated with protection

por Anderson, Elizabeth M., Goodwin, Eileen C., Verma, Anurag, Arevalo, Claudia P., Bolton, Marcus J., Weirick, Madison E., Gouma, Sigrid, McAllister, Christopher M., Christensen, Shannon R., Weaver, JoEllen, Hicks, Phillip, Manzoni, Tomaz B., Oniyide, Oluwatosin, Ramage, Holly, Mathew, Divij, Baxter, Amy E., Oldridge, Derek A., Greenplate, Allison R., Wu, Jennifer E., Alanio, Cécile, D’Andrea, Kurt, Kuthuru, Oliva, Dougherty, Jeanette, Pattekar, Ajinkya, Kim, Justin, Han, Nicholas, Apostolidis, Sokratis A., Huang, Alex C., Vella, Laura A., Wherry, E. John, Meyer, Nuala J., Cherry, Sara, Bates, Paul, Rader, Daniel J., Hensley, Scott E.
Publicado 2020

Signaling through FcγRIIA and the C5a-C5aR pathway mediates platelet hyperactivation in COVID-19

por Apostolidis, Sokratis A., Sarkar, Amrita, Giannini, Heather M., Goel, Rishi R., Mathew, Divij, Suzuki, Aae, Baxter, Amy E., Greenplate, Allison R., Alanio, Cécile, Abdel-Hakeem, Mohamed, Oldridge, Derek A., Giles, Josephine, Wu, Jennifer E., Chen, Zeyu, Huang, Yinghui Jane, Pattekar, Ajinkya, Manne, Sasikanth, Kuthuru, Oliva, Dougherty, Jeanette, Weiderhold, Brittany, Weisman, Ariel R., Ittner, Caroline A. G., Gouma, Sigrid, Dunbar, Debora, Frank, Ian, Huang, Alexander C., Vella, Laura A., Reilly, John P., Hensley, Scott E., Rauova, Lubica, Zhao, Liang, Meyer, Nuala J., Poncz, Mortimer, Abrams, Charles S., Wherry, E. John
Publicado 2021

Signaling Through FcγRIIA and the C5a-C5aR Pathway Mediate Platelet Hyperactivation in COVID-19

por Apostolidis, Sokratis A., Sarkar, Amrita, Giannini, Heather M., Goel, Rishi R., Mathew, Divij, Suzuki, Aae, Baxter, Amy E., Greenplate, Allison R., Alanio, Cécile, Abdel-Hakeem, Mohamed, Oldridge, Derek A., Giles, Josephine R., Wu, Jennifer E., Chen, Zeyu, Huang, Yinghui Jane, Belman, Jonathan, Pattekar, Ajinkya, Manne, Sasikanth, Kuthuru, Oliva, Dougherty, Jeanette, Weiderhold, Brittany, Weisman, Ariel R., Ittner, Caroline A. G., Gouma, Sigrid, Dunbar, Debora, Frank, Ian, Huang, Alexander C., Vella, Laura A., Reilly, John P., Hensley, Scott E., Rauova, Lubica, Zhao, Liang, Meyer, Nuala J., Poncz, Mortimer, Abrams, Charles S., Wherry, E. John
Publicado 2022

Deep immune profiling of COVID-19 patients reveals patient heterogeneity and distinct immunotypes with implications for therapeutic interventions

por Mathew, Divij, Giles, Josephine R., Baxter, Amy E., Greenplate, Allison R., Wu, Jennifer E., Alanio, Cécile, Oldridge, Derek A., Kuri-Cervantes, Leticia, Pampena, M. Betina, D’Andrea, Kurt, Manne, Sasikanth, Chen, Zeyu, Huang, Yinghui Jane, Reilly, John P., Weisman, Ariel R, Ittner, Caroline A.G., Kuthuru, Oliva, Dougherty, Jeanette, Nzingha, Kito, Han, Nicholas, Kim, Justin, Pattekar, Ajinkya, Goodwin, Eileen C., Anderson, Elizabeth M., Weirick, Madison E., Gouma, Sigrid, Arevalo, Claudia P., Bolton, Marcus J., Chen, Fang, Lacey, Simon F., Hensley, Scott E., Apostolidis, Sokratis, Huang, Alexander C., Vella, Laura A., Betts, Michael R., Meyer, Nuala J., Wherry, E. John
Publicado 2020

Seasonal human coronavirus antibodies are boosted upon SARS-CoV-2 infection but not associated with protection

por Anderson, Elizabeth M., Goodwin, Eileen C., Verma, Anurag, Arevalo, Claudia P., Bolton, Marcus J., Weirick, Madison E., Gouma, Sigrid, McAllister, Christopher M., Christensen, Shannon R., Weaver, JoEllen, Hicks, Philip, Manzoni, Tomaz B., Oniyide, Oluwatosin, Ramage, Holly, Mathew, Divij, Baxter, Amy E., Oldridge, Derek A., Greenplate, Allison R., Wu, Jennifer E., Alanio, Cécile, D’Andrea, Kurt, Kuthuru, Oliva, Dougherty, Jeanette, Pattekar, Ajinkya, Kim, Justin, Han, Nicholas, Apostolidis, Sokratis A., Huang, Alex C., Vella, Laura A., Kuri-Cervantes, Leticia, Pampena, M. Betina, Betts, Michael R., Wherry, E. John, Meyer, Nuala J., Cherry, Sara, Bates, Paul, Rader, Daniel J., Hensley, Scott E.
Publicado 2021

Sotigalimab and/or nivolumab with chemotherapy in first-line metastatic pancreatic cancer: clinical and immunologic analyses from the randomized phase 2 PRINCE trial

por Padrón, Lacey J., Maurer, Deena M., O’Hara, Mark H., O’Reilly, Eileen M., Wolff, Robert A., Wainberg, Zev A., Ko, Andrew H., Fisher, George, Rahma, Osama, Lyman, Jaclyn P., Cabanski, Christopher R., Yu, Jia Xin, Pfeiffer, Shannon M., Spasic, Marko, Xu, Jingying, Gherardini, Pier Federico, Karakunnel, Joyson, Mick, Rosemarie, Alanio, Cécile, Byrne, Katelyn T., Hollmann, Travis J., Moore, Jonni S., Jones, Derek D., Tognetti, Marco, Chen, Richard O., Yang, Xiaodong, Salvador, Lisa, Wherry, E. John, Dugan, Ute, O’Donnell-Tormey, Jill, Butterfield, Lisa H., Hubbard-Lucey, Vanessa M., Ibrahim, Ramy, Fairchild, Justin, Bucktrout, Samantha, LaVallee, Theresa M., Vonderheide, Robert H.
Publicado 2022

Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications

por Mathew, Divij, Giles, Josephine R., Baxter, Amy E., Oldridge, Derek A., Greenplate, Allison R., Wu, Jennifer E., Alanio, Cécile, Kuri-Cervantes, Leticia, Pampena, M. Betina, D’Andrea, Kurt, Manne, Sasikanth, Chen, Zeyu, Huang, Yinghui Jane, Reilly, John P., Weisman, Ariel R., Ittner, Caroline A. G., Kuthuru, Oliva, Dougherty, Jeanette, Nzingha, Kito, Han, Nicholas, Kim, Justin, Pattekar, Ajinkya, Goodwin, Eileen C., Anderson, Elizabeth M., Weirick, Madison E., Gouma, Sigrid, Arevalo, Claudia P., Bolton, Marcus J., Chen, Fang, Lacey, Simon F., Ramage, Holly, Cherry, Sara, Hensley, Scott E., Apostolidis, Sokratis A., Huang, Alexander C., Vella, Laura A., Betts, Michael R., Meyer, Nuala J., Wherry, E. John
Publicado 2020

Deep immune profiling of MIS-C demonstrates marked but transient immune activation compared to adult and pediatric COVID-19

por Vella, Laura A., Giles, Josephine R., Baxter, Amy E., Oldridge, Derek A., Diorio, Caroline, Kuri-Cervantes, Leticia, Alanio, Cécile, Pampena, M. Betina, Wu, Jennifer E., Chen, Zeyu, Huang, Yinghui Jane, Anderson, Elizabeth M., Gouma, Sigrid, McNerney, Kevin O., Chase, Julie, Burudpakdee, Chakkapong, Lee, Jessica H., Apostolidis, Sokratis A., Huang, Alexander C., Mathew, Divij, Kuthuru, Oliva, Goodwin, Eileen C., Weirick, Madison E., Bolton, Marcus J., Arevalo, Claudia P., Ramos, Andre, Jasen, CJ, Conrey, Peyton E, Sayed, Samir, Giannini, Heather M., D’Andrea, Kurt, Meyer, Nuala J., Behrens, Edward M., Bassiri, Hamid, Hensley, Scott E., Henrickson, Sarah E., Teachey, David T., Betts, Michael R., Wherry, E. John
Publicado 2021

CD8 T cells compensate for impaired humoral immunity in COVID-19 patients with hematologic cancer

por Bange, Erin M., Han, Nicholas A., Wileyto, Paul, Kim, Justin Y., Gouma, Sigrid, Robinson, James, Greenplate, Allison R., Porterfield, Florence, Owoyemi, Olutosin, Naik, Karan, Zheng, Cathy, Galantino, Michael, Weisman, Ariel R., Ittner, Caroline A.G., Kugler, Emily M., Baxter, Amy E., Oniyide, Olutwatosin, Agyekum, Roseline S., Dunn, Thomas G., Jones, Tiffanie K., Giannini, Heather M., Weirick, Madison E., McAllister, Christopher M., Babady, N. Esther, Kumar, Anita, Widman, Adam J, DeWolf, Susan, Boutemine, Sawsan R, Roberts, Charlotte, Budzik, Krista R, Tollett, Susan, Wright, Carla, Perloff, Tara, Sun, Lova, Mathew, Divij, Giles, Josephine R., Oldridge, Derek A., Wu, Jennifer E., Alanio, Cécile, Adamski, Sharon, Garfall, Alfred L., Vella, Laura, Kerr, Samuel J., Cohen, Justine V., Oyer, Randall A., Massa, Ryan, Maillard, Ivan P., Maxwell, Kara N., Reilly, John P., Maslak, Peter G., Vonderheide, Robert H., Wolchok, Jedd D., Hensley, Scott E., Wherry, E. John, Meyer, Nuala, DeMichele, Angela M., Vardhana, Santosha A., Mamtani, Ronac, Huang, Alexander C.
Publicado 2021