Mutations in the TERC template sequence can be incorporated into the telomeres of human tumors

por Sharaf, Radwa, Frampton, Garrett M., Albacker, Lee A.
Publicado 2022

A pan-cancer landscape of telomeric content shows that RAD21 and HGF alterations are associated with longer telomeres

por Sharaf, Radwa, Montesion, Meagan, Hopkins, Julia F., Song, Jiarong, Frampton, Garrett M., Albacker, Lee A.
Publicado 2022

Pan-cancer analysis of the effect of biopsy site on tumor mutational burden observations

por Papillon-Cavanagh, Simon, Hopkins, Julia F., Ramkissoon, Shakti H., Albacker, Lee A., Walsh, Alice M.
Publicado 2021

Genomic analysis of 63,220 tumors reveals insights into tumor uniqueness and targeted cancer immunotherapy strategies

por Hartmaier, Ryan J., Charo, Jehad, Fabrizio, David, Goldberg, Michael E., Albacker, Lee A., Pao, William, Chmielecki, Juliann
Publicado 2017

Loss of function JAK1 mutations occur at high frequency in cancers with microsatellite instability and are suggestive of immune evasion

por Albacker, Lee A., Wu, Jeremy, Smith, Peter, Warmuth, Markus, Stephens, Philip J., Zhu, Ping, Yu, Lihua, Chmielecki, Juliann
Publicado 2017

Deletions on 9p21 are associated with worse outcomes after anti-PD-1/PD-L1 monotherapy but not chemoimmunotherapy

por Ebot, Ericka M., Duncan, Daniel L., Tolba, Khaled, Fabrizio, David, Frampton, Garrett M., Comment, Leah A., Albacker, Lee A.
Publicado 2022

A pan-sarcoma landscape of telomeric content shows that alterations in RAD51B and GID4 are associated with higher telomeric content

por Sharaf, Radwa, Jin, Dexter X., Grady, John, Napier, Christine, Ebot, Ericka, Frampton, Garrett M., Albacker, Lee A., Thomas, David M., Montesion, Meagan
Publicado 2023

Response to rapamycin analogs but not PD-1 inhibitors in PTEN-mutated metastatic non-small-cell lung cancer with high tumor mutational burden

por Parikh, Ankur R, Ali, Siraj M, Schrock, Alexa B, Albacker, Lee A, Miller, Vincent A, Stephens, Phil J, Crilley, Pamela, Markman, Maurie
Publicado 2018

The genomic landscape of metastatic breast cancer: Insights from 11,000 tumors

por Rinaldi, Jacob, Sokol, Ethan S., Hartmaier, Ryan J., Trabucco, Sally E., Frampton, Garrett M., Goldberg, Michael E., Albacker, Lee A., Daemen, Anneleen, Manning, Gerard
Publicado 2020

Pan-cancer landscape of CD274 (PD-L1) rearrangements in 283,050 patient samples, its correlation with PD-L1 protein expression, and immunotherapy response

por Kelly, Andrew D, Murugesan, Karthikeyan, Kuang, Zheng, Montesion, Meagan, Ross, Jeffrey S, Albacker, Lee A, Huang, Richard S P, Lin, Douglas I, Demirci, Umut, Creeden, James
Publicado 2021

A Fungal Glycosphingolipid Directly Activates Natural Killer T Cells and Rapidly Induces Airways Disease

por Albacker, Lee A., Chaudhary, Vinod, Chang, Ya-Jen, Kim, Hye Young, Chuang, Ya-Ting, Pichavant, Muriel, DeKruyff, Rosemarie H., Savage, Paul B., Umetsu, Dale T.
Publicado 2013

Pan-cancer landscape of CD274 (PD-L1) copy number changes in 244 584 patient samples and the correlation with PD-L1 protein expression

por Huang, Richard S.P., Murugesan, Karthikeyan, Montesion, Meagan, Pavlick, Dean C., Mata, Douglas A., Hiemenz, Matthew C., Decker, Brennan, Frampton, Garrett, Albacker, Lee A., Ross, Jeffrey S.
Publicado 2021

Tissue expression of PD-L1 mediates peripheral T cell tolerance

por Keir, Mary E., Liang, Spencer C., Guleria, Indira, Latchman, Yvette E., Qipo, Andi, Albacker, Lee A., Koulmanda, Maria, Freeman, Gordon J., Sayegh, Mohamed H., Sharpe, Arlene H.
Publicado 2006

Computational and Functional Analyses of HER2 Mutations Reveal Allosteric Activation Mechanisms and Altered Pharmacologic Effects

por Ishiyama, Noboru, O'Connor, Matthew, Salomatov, Andrei, Romashko, Darlene, Thakur, Shalabh, Mentes, Ahmet, Hopkins, Julia F., Frampton, Garrett M., Albacker, Lee A., Kohlmann, Anna, Roberts, Christopher, Buck, Elizabeth
Publicado 2023

Evaluation of tissue- and plasma-derived tumor mutational burden (TMB) and genomic alterations of interest in CheckMate 848, a study of nivolumab combined with ipilimumab and nivol...

por He, Jie, Kalinava, Natallia, Doshi, Parul, Pavlick, Dean C, Albacker, Lee A, Ebot, Ericka M, Tukachinsky, Hanna, Pratt, James, Fusaro, Gina, Oxnard, Geoffrey R, Green, George, Fabrizio, David, Baden, Jonathan
Publicado 2023

Predictive Biomarkers for Immune Checkpoint Inhibitors in Metastatic Breast Cancer

por Sivapiragasam, Abirami, Ashok Kumar, Prashanth, Sokol, Ethan S., Albacker, Lee A., Killian, Jonathan K., Ramkissoon, Shakti H., Huang, Richard S. P., Severson, Eric A., Brown, Charlotte A., Danziger, Natalie, McGregor, Kimberly, Ross, Jeffrey S.
Publicado 2020

Deletion of the MAD2L1 spindle assembly checkpoint gene is tolerated in mouse models of acute T-cell lymphoma and hepatocellular carcinoma

por Foijer, Floris, Albacker, Lee A, Bakker, Bjorn, Spierings, Diana C, Yue, Ying, Xie, Stephanie Z, Davis, Stephanie, Lutum-Jehle, Annegret, Takemoto, Darin, Hare, Brian, Furey, Brinley, Bronson, Roderick T, Lansdorp, Peter M, Bradley, Allan, Sorger, Peter K
Publicado 2017

HRAS Mutations Define a Distinct Subgroup in Head and Neck Squamous Cell Carcinoma

por Coleman, Niamh, Marcelo, Kathrina L., Hopkins, Julia F., Khan, Nusrat Israr, Du, Robyn, Hong, Lingzhi, Park, Edward, Balsara, Binaifer, Leoni, Mollie, Pickering, Curtis, Myers, Jeffrey, Heymach, John, Albacker, Lee A., Hong, David, Gillison, Maura, Le, Xiuning
Publicado 2023

Association of CD274 (PD-L1) Copy Number Changes with Immune Checkpoint Inhibitor Clinical Benefit in Non-Squamous Non-Small Cell Lung Cancer

por Murugesan, Karthikeyan, Jin, Dexter X, Comment, Leah A, Fabrizio, David, Hegde, Priti S, Elvin, Julia A, Alexander, Brian, Levy, Mia A, Frampton, Garrett M, Montesion, Meagan, Roychowdhury, Sameek, Kurzrock, Razelle, Ross, Jeffrey S, Albacker, Lee A, Huang, Richard S P
Publicado 2022

Predicting EGFR mutational status from pathology images using a real-world dataset

por Pao, James J., Biggs, Mikayla, Duncan, Daniel, Lin, Douglas I., Davis, Richard, Huang, Richard S. P., Ferguson, Donna, Janovitz, Tyler, Hiemenz, Matthew C., Eddy, Nathanial R., Lehnert, Erik, Cabili, Moran N., Frampton, Garrett M., Hegde, Priti S., Albacker, Lee A.
Publicado 2023