Comprehensive Transcriptomic Profiling of Murine Osteoclast Differentiation Reveals Novel Differentially Expressed Genes and LncRNAs

por Toor, Salman M., Wani, Sachin, Albagha, Omar M. E.
Publicado 2021

Integrated epigenome, whole genome sequence and metabolome analyses identify novel multi-omics pathways in type 2 diabetes: a Middle Eastern study

por Yousri, Noha A., Albagha, Omar M. E., Hunt, Steven C.
Publicado 2023

Epigenetic DNA Methylation Signatures Associated With the Severity of Paget’s Disease of Bone

por Diboun, Ilhame, Wani, Sachin, Ralston, Stuart H., Albagha, Omar M. E.
Publicado 2022

Identification of a Gene Panel Predictive of Triple-Negative Breast Cancer Response to Neoadjuvant Chemotherapy Employing Transcriptomic and Functional Validation

por Vishnubalaji, Radhakrishnan, Abdel-Razeq, Hikmat, Gehani, Salahddin, Albagha, Omar M. E., Alajez, Nehad M.
Publicado 2022

Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits

por Thareja, Gaurav, Al-Sarraj, Yasser, Belkadi, Aziz, Almotawa, Maryam, Suhre, Karsten, Albagha, Omar M. E.
Publicado 2021

Identification of PCSK9-like human gene knockouts using metabolomics, proteomics, and whole-genome sequencing in a consanguineous population

por Belkadi, Aziz, Thareja, Gaurav, Abbaszadeh, Fatemeh, Badii, Ramin, Fauman, Eric, Albagha, Omar M.E., Suhre, Karsten
Publicado 2022

The Paget's disease of bone risk gene PML is a negative regulator of osteoclast differentiation and bone resorption

por Wani, Sachin, Daroszewska, Anna, Salter, Donald M., van ‘t Hof, Rob J., Ralston, Stuart H., Albagha, Omar M. E.
Publicado 2022

Optineurin Negatively Regulates Osteoclast Differentiation by Modulating NF-κB and Interferon Signaling: Implications for Paget’s Disease

por Obaid, Rami, Wani, Sachin E., Azfer, Asim, Hurd, Toby, Jones, Ruth, Cohen, Philip, Ralston, Stuart H., Albagha, Omar M.E.
Publicado 2015

Targeted sequencing of the Paget's disease associated 14q32 locus identifies several missense coding variants in RIN3 that predispose to Paget's disease of bone

por Vallet, Mahéva, Soares, Dinesh C., Wani, Sachin, Sophocleous, Antonia, Warner, Jon, Salter, Donald M., Ralston, Stuart H., Albagha, Omar M.E.
Publicado 2015

Transcriptome profiling and network enrichment analyses identify subtype-specific therapeutic gene targets for breast cancer and their microRNA regulatory networks

por Elango, Ramesh, Rashid, Sameera, Vishnubalaji, Radhakrishnan, Al-Sarraf, Reem, Akhtar, Mohammed, Ouararhni, Khalid, Decock, Julie, Albagha, Omar M. E., Alajez, Nehad M.
Publicado 2023

Family-Based Genome-Wide Association Study of Autism Spectrum Disorder in Middle Eastern Families

por Al-Sarraj, Yasser, Al-Dous, Eman, Taha, Rowaida Z., Ahram, Dina, Alshaban, Fouad, Tolfat, Mohammed, El-Shanti, Hatem, Albagha, Omar M.E.
Publicado 2021

Novel KRAS Gene Mutations in Sporadic Colorectal Cancer

por Naser, Walid M., Shawarby, Mohamed A., Al-Tamimi, Dalal M., Seth, Arun, Al-Quorain, Abdulaziz, Nemer, Areej M. Al, Albagha, Omar M. E.
Publicado 2014

The Genetic Spectrum of Maturity-Onset Diabetes of the Young (MODY) in Qatar, a Population-Based Study

por Elashi, Asma A., Toor, Salman M., Diboun, Ilhame, Al-Sarraj, Yasser, Taheri, Shahrad, Suhre, Karsten, Abou-Samra, Abdul Badi, Albagha, Omar M. E.
Publicado 2022

Ratios of Acetaminophen Metabolites Identify New Loci of Pharmacogenetic Relevance in a Genome-Wide Association Study

por Thareja, Gaurav, Evans, Anne M., Wood, Spencer D., Stephan, Nisha, Zaghlool, Shaza, Halama, Anna, Kastenmüller, Gabi, Belkadi, Aziz, Albagha, Omar M. E., Suhre, Karsten
Publicado 2022

The Prevalence and Genetic Spectrum of Familial Hypercholesterolemia in Qatar Based on Whole Genome Sequencing of 14,000 Subjects

por Diboun, Ilhame, Al-Sarraj, Yasser, Toor, Salman M., Mohammed, Shaban, Qureshi, Nadeem, Al Hail, Moza S. H., Jayyousi, Amin, Al Suwaidi, Jassim, Albagha, Omar M. E.
Publicado 2022

Differences and commonalities in the genetic architecture of protein quantitative trait loci in European and Arab populations

por Thareja, Gaurav, Belkadi, Aziz, Arnold, Matthias, Albagha, Omar M E, Graumann, Johannes, Schmidt, Frank, Grallert, Harald, Peters, Annette, Gieger, Christian, Consortium, The Qatar Genome Program Research, Suhre, Karsten
Publicado 2022

Metabolic and proteomic signatures of type 2 diabetes subtypes in an Arab population

por Zaghlool, Shaza B., Halama, Anna, Stephan, Nisha, Gudmundsdottir, Valborg, Gudnason, Vilmundur, Jennings, Lori L., Thangam, Manonanthini, Ahlqvist, Emma, Malik, Rayaz A., Albagha, Omar M. E., Abou‑Samra, Abdul Badi, Suhre, Karsten
Publicado 2022

Identification of Novel Circulating miRNAs in Patients with Acute Ischemic Stroke

por Aldous, Eman K., Toor, Salman M., Parray, Aijaz, Al-Sarraj, Yasser, Diboun, Ilhame, Abdelalim, Essam M., Arredouani, Abdelilah, El-Agnaf, Omar, Thornalley, Paul J., Akhtar, Naveed, Pananchikkal, Sajitha V., Shuaib, Ashfaq, Alajez, Nehad M., Albagha, Omar M. E.
Publicado 2022

Circulating MicroRNA Profiling Identifies Distinct MicroRNA Signatures in Acute Ischemic Stroke and Transient Ischemic Attack Patients

por Toor, Salman M., Aldous, Eman K., Parray, Aijaz, Akhtar, Naveed, Al-Sarraj, Yasser, Abdelalim, Essam M., Arredouani, Abdelilah, El-Agnaf, Omar, Thornalley, Paul J., Pananchikkal, Sajitha V., Pir, Ghulam Jeelani, Ayadathil, Raheem, Shuaib, Ashfaq, Alajez, Nehad M., Albagha, Omar M. E.
Publicado 2022

Identification of distinct circulating microRNAs in acute ischemic stroke patients with type 2 diabetes mellitus

por Toor, Salman M., Aldous, Eman K., Parray, Aijaz, Akhtar, Naveed, Al-Sarraj, Yasser, Abdelalim, Essam M., Arredouani, Abdelilah, El-Agnaf, Omar, Thornalley, Paul J., Pananchikkal, Sajitha V., Pir, Ghulam Jeelani, Kuni, Raheem Ayadathil Thazhhe, Shuaib, Ashfaq, Alajez, Nehad M., Albagha, Omar M. E.
Publicado 2022