Selective inhibition of PfA-M1, over PfA-M17, by an amino-benzosuberone derivative blocks malaria parasites development in vitro and in vivo

por Bounaadja, Lotfi, Schmitt, Marjorie, Albrecht, Sébastien, Mouray, Elisabeth, Tarnus, Céline, Florent, Isabelle
Publicado 2017

Allosteric inhibition of aminopeptidase N functions related to tumor growth and virus infection

por Santiago, César, Mudgal, Gaurav, Reguera, Juan, Recacha, Rosario, Albrecht, Sébastien, Enjuanes, Luis, Casasnovas, José M.
Publicado 2017

Aminobenzosuberone Scaffold as a Modular Chemical Tool for the Inhibition of Therapeutically Relevant M1 Aminopeptidases

por Salomon, Emmanuel, Schmitt, Marjorie, Marapaka, Anil Kumar, Stamogiannos, Athanasios, Revelant, Germain, Schmitt, Céline, Alavi, Sarah, Florent, Isabelle, Addlagatta, Anthony, Stratikos, Efstratios, Tarnus, Céline, Albrecht, Sébastien
Publicado 2018

Discovery of Indoline-2-carboxamide Derivatives as a New Class of Brain-Penetrant Inhibitors of Trypanosoma brucei

por Cleghorn, Laura A. T., Albrecht, Sébastien, Stojanovski, Laste, Simeons, Frederick R. J., Norval, Suzanne, Kime, Robert, Collie, Iain T., De Rycker, Manu, Campbell, Lorna, Hallyburton, Irene, Frearson, Julie A., Wyatt, Paul G., Read, Kevin D., Gilbert, Ian H.
Publicado 2015

Development of a 2,4-Diaminothiazole Series for the Treatment of Human African Trypanosomiasis Highlights the Importance of Static–Cidal Screening of Analogues

por Cleghorn, Laura A. T., Wall, Richard J., Albrecht, Sébastien, MacGowan, Stuart A., Norval, Suzanne, De Rycker, Manu, Woodland, Andrew, Spinks, Daniel, Thompson, Stephen, Patterson, Stephen, Corpas Lopez, Victoriano, Dey, Gourav, Collie, Iain T., Hallyburton, Irene, Kime, Robert, Simeons, Frederick R. C., Stojanovski, Laste, Frearson, Julie A., Wyatt, Paul G., Read, Kevin D., Gilbert, Ian H., Wyllie, Susan
Publicado 2023