Pathology-specific experimental antivenoms for haemotoxic snakebite: The impact of immunogen diversity on the in vitro cross-reactivity and in vivo neutralisation of geographically...

por Alomran, Nessrin, Alsolaiss, Jaffer, Albulescu, Laura-Oana, Crittenden, Edouard, Harrison, Robert A., Ainsworth, Stuart, Casewell, Nicholas R.
Publicado 2021

Correction: Pathology-specific experimental antivenoms for haemotoxic snakebite: The impact of immunogen diversity on the in vitro cross-reactivity and in vivo neutralisation of ge...

por Alomran, Nessrin, Alsolaiss, Jaffer, Albulescu, Laura-Oana, Crittenden, Edouard, Harrison, Robert A., Ainsworth, Stuart, Casewell, Nicholas R.
Publicado 2022

A Quantitative, High-Throughput Reverse Genetic Screen Reveals Novel Connections between Pre–mRNA Splicing and 5′ and 3′ End Transcript Determinants

por Albulescu, Laura-Oana, Sabet, Nevin, Gudipati, Mohanram, Stepankiw, Nicholas, Bergman, Zane J., Huffaker, Tim C., Pleiss, Jeffrey A.
Publicado 2012

Neutralising effects of small molecule toxin inhibitors on nanofractionated coagulopathic Crotalinae snake venoms

por Xie, Chunfang, Slagboom, Julien, Albulescu, Laura-Oana, Somsen, Govert W., Vonk, Freek J., Casewell, Nicholas R., Kool, Jeroen
Publicado 2020

Neutralizing Effects of Small Molecule Inhibitors and Metal Chelators on Coagulopathic Viperinae Snake Venom Toxins

por Xie, Chunfang, Albulescu, Laura-Oana, Bittenbinder, Mátyás A., Somsen, Govert W., Vonk, Freek J., Casewell, Nicholas R., Kool, Jeroen
Publicado 2020

In Vitro Immunological Cross-Reactivity of Thai Polyvalent and Monovalent Antivenoms with Asian Viper Venoms

por Chaisakul, Janeyuth, Rusmili, Muhamad Rusdi Ahmad, Alsolaiss, Jaffer, Albulescu, Laura-Oana, Harrison, Robert A., Othman, Iekhsan, Casewell, Nicholas R.
Publicado 2020

The Search for Natural and Synthetic Inhibitors That Would Complement Antivenoms as Therapeutics for Snakebite Envenoming

por Gutiérrez, José María, Albulescu, Laura-Oana, Clare, Rachel H., Casewell, Nicholas R., Abd El-Aziz, Tarek Mohamed, Escalante, Teresa, Rucavado, Alexandra
Publicado 2021

RNase H2, mutated in Aicardi‐Goutières syndrome, resolves co-transcriptional R-loops to prevent DNA breaks and inflammation

por Cristini, Agnese, Tellier, Michael, Constantinescu, Flavia, Accalai, Clelia, Albulescu, Laura Oana, Heiringhoff, Robin, Bery, Nicolas, Sordet, Olivier, Murphy, Shona, Gromak, Natalia
Publicado 2022

Antivenom Neutralization of Coagulopathic Snake Venom Toxins Assessed by Bioactivity Profiling Using Nanofractionation Analytics

por Xie, Chunfang, Slagboom, Julien, Albulescu, Laura-Oana, Bruyneel, Ben, Still, Kristina B. M., Vonk, Freek J., Somsen, Govert W., Casewell, Nicholas R., Kool, Jeroen
Publicado 2020

Varespladib Inhibits the Phospholipase A(2) and Coagulopathic Activities of Venom Components from Hemotoxic Snakes

por Xie, Chunfang, Albulescu, Laura-Oana, Still, Kristina B. M., Slagboom, Julien, Zhao, Yumei, Jiang, Zhengjin, Somsen, Govert W., Vonk, Freek J., Casewell, Nicholas R., Kool, Jeroen
Publicado 2020

A therapeutic combination of two small molecule toxin inhibitors provides broad preclinical efficacy against viper snakebite

por Albulescu, Laura-Oana, Xie, Chunfang, Ainsworth, Stuart, Alsolaiss, Jaffer, Crittenden, Edouard, Dawson, Charlotte A., Softley, Rowan, Bartlett, Keirah E., Harrison, Robert A., Kool, Jeroen, Casewell, Nicholas R.
Publicado 2020

Author Correction: A therapeutic combination of two small molecule toxin inhibitors provides broad preclinical efficacy against viper snakebite

por Albulescu, Laura-Oana, Xie, Chunfang, Ainsworth, Stuart, Alsolaiss, Jaffer, Crittenden, Edouard, Dawson, Charlotte A., Softley, Rowan, Bartlett, Keirah E., Harrison, Robert A., Kool, Jeroen, Casewell, Nicholas R.
Publicado 2021

A Decoy-Receptor Approach Using Nicotinic Acetylcholine Receptor Mimics Reveals Their Potential as Novel Therapeutics Against Neurotoxic Snakebite

por Albulescu, Laura-Oana, Kazandjian, Taline, Slagboom, Julien, Bruyneel, Ben, Ainsworth, Stuart, Alsolaiss, Jaffer, Wagstaff, Simon C., Whiteley, Gareth, Harrison, Robert A., Ulens, Chris, Kool, Jeroen, Casewell, Nicholas R.
Publicado 2019

Solenodon genome reveals convergent evolution of venom in eulipotyphlan mammals

por Casewell, Nicholas R., Petras, Daniel, Card, Daren C., Suranse, Vivek, Mychajliw, Alexis M., Richards, David, Koludarov, Ivan, Albulescu, Laura-Oana, Slagboom, Julien, Hempel, Benjamin-Florian, Ngum, Neville M., Kennerley, Rosalind J., Brocca, Jorge L., Whiteley, Gareth, Harrison, Robert A., Bolton, Fiona M. S., Debono, Jordan, Vonk, Freek J., Alföldi, Jessica, Johnson, Jeremy, Karlsson, Elinor K., Lindblad-Toh, Kerstin, Mellor, Ian R., Süssmuth, Roderich D., Fry, Bryan G., Kuruppu, Sanjaya, Hodgson, Wayne C., Kool, Jeroen, Castoe, Todd A., Barnes, Ian, Sunagar, Kartik, Undheim, Eivind A. B., Turvey, Samuel T.
Publicado 2019