Challenges in drug discovery targeting TriTryp diseases with an emphasis on leishmaniasis

por Alcântara, Laura M., Ferreira, Thalita C.S., Gadelha, Fernanda R., Miguel, Danilo C.
Publicado 2018

Expression of a Cutinase of Moniliophthora roreri with Polyester and PET-Plastic Residues Degradation Activity

por Vázquez-Alcántara, Laura, Oliart-Ros, Rosa María, García-Bórquez, Arturo, Peña-Montes, Carolina
Publicado 2021

Drug Discovery for Chagas Disease: Impact of Different Host Cell Lines on Assay Performance and Hit Compound Selection

por Franco, Caio Haddad, Alcântara, Laura Maria, Chatelain, Eric, Freitas-Junior, Lucio, Moraes, Carolina Borsoi
Publicado 2019

A Multi-Species Phenotypic Screening Assay for Leishmaniasis Drug Discovery Shows That Active Compounds Display a High Degree of Species-Specificity

por Alcântara, Laura M., Ferreira, Thalita C. S., Fontana, Vanessa, Chatelain, Eric, Moraes, Carolina B., Freitas-Junior, Lucio H.
Publicado 2020

Microscopy-based phenotypic profiling of infection by Staphylococcus aureus clinical isolates reveals intracellular lifestyle as a prevalent feature

por Rodrigues Lopes, Ines, Alcantara, Laura Maria, Silva, Ricardo Jorge, Josse, Jerome, Vega, Elena Pedrero, Cabrerizo, Ana Marina, Bonhomme, Melanie, Lopez, Daniel, Laurent, Frederic, Vandenesch, Francois, Mano, Miguel, Eulalio, Ana
Publicado 2022

Identification of Inhibitors to Trypanosoma cruzi Sirtuins Based on Compounds Developed to Human Enzymes

por Matutino Bastos, Tanira, Botelho Pereira Soares, Milena, Haddad Franco, Caio, Alcântara, Laura, Antonini, Lorenzo, Sabatino, Manuela, Mautone, Nicola, Holanda Freitas-Junior, Lucio, Moraes, Carolina Borsoi, Ragno, Rino, Rotili, Dante, Schenkman, Sergio, Mai, Antonello, Silvio Moretti, Nilmar
Publicado 2020

Chroman-4-One Derivatives Targeting Pteridine Reductase 1 and Showing Anti-Parasitic Activity

por Di Pisa, Flavio, Landi, Giacomo, Dello Iacono, Lucia, Pozzi, Cecilia, Borsari, Chiara, Ferrari, Stefania, Santucci, Matteo, Santarem, Nuno, Cordeiro-da-Silva, Anabela, Moraes, Carolina B., Alcantara, Laura M., Fontana, Vanessa, Freitas-Junior, Lucio H., Gul, Sheraz, Kuzikov, Maria, Behrens, Birte, Pöhner, Ina, Wade, Rebecca C., Costi, Maria Paola, Mangani, Stefano
Publicado 2017

Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery

por Linciano, Pasquale, Dawson, Alice, Pöhner, Ina, Costa, David M., Sá, Monica S., Cordeiro-da-Silva, Anabela, Luciani, Rosaria, Gul, Sheraz, Witt, Gesa, Ellinger, Bernhard, Kuzikov, Maria, Gribbon, Philip, Reinshagen, Jeanette, Wolf, Markus, Behrens, Birte, Hannaert, Véronique, Michels, Paul A. M., Nerini, Erika, Pozzi, Cecilia, di Pisa, Flavio, Landi, Giacomo, Santarem, Nuno, Ferrari, Stefania, Saxena, Puneet, Lazzari, Sandra, Cannazza, Giuseppe, Freitas-Junior, Lucio H., Moraes, Carolina B., Pascoalino, Bruno S., Alcântara, Laura M., Bertolacini, Claudia P., Fontana, Vanessa, Wittig, Ulrike, Müller, Wolfgang, Wade, Rebecca C., Hunter, William N., Mangani, Stefano, Costantino, Luca, Costi, Maria P.
Publicado 2017