Targeting SHP2 phosphatase in breast cancer overcomes RTK-mediated resistance to PI3K inhibitors

por Heynen, Guus J. J. E., Lisek, Kamil, Vogel, Regina, Wulf-Goldenberg, Annika, Alcaniz, Joshua, Montaudon, Elodie, Marangoni, Elisabetta, Birchmeier, Walter
Publicado 2022

Clinically relevant glioblastoma patient-derived xenograft models to guide drug development and identify molecular signatures

por Alcaniz, Joshua, Winkler, Lars, Dahlmann, Mathias, Becker, Michael, Orthmann, Andrea, Haybaeck, Johannes, Krassnig, Stefanie, Skofler, Christina, Kratzsch, Tobias, Kuhn, Susanne A., Jödicke, Andreas, Linnebacher, Michael, Fichtner, Iduna, Walther, Wolfgang, Hoffmann, Jens
Publicado 2023

Decreased eukaryotic initiation factors expression upon temozolomide treatment—potential novel implications for eIFs in glioma therapy

por Krassnig, Stefanie, Leber, Stefan L., Orthmann, Andrea, Golob-Schwarzl, Nicole, Huber, Heinrich Johann, Wohlrab, Christina, Skofler, Christina, Pennauer, Mirjam, Raicht, Andrea, Birkl-Toeglhofer, Anna Maria, Naumann, Michael, Mahdy-Ali, Kariem, von Campe, Gord, Leoni, Marlene, Alcaniz, Joshua, Hoffmann, Jens, Wälchli, Thomas, Weis, Serge, Benesch, Martin, Haybaeck, Johannes
Publicado 2023