Discovering functional modules by identifying recurrent and mutually exclusive mutational patterns in tumors

por Miller, Christopher A, Settle, Stephen H, Sulman, Erik P, Aldape, Kenneth D, Milosavljevic, Aleksandar
Publicado 2011

A Mosaic Mouse Model of Astrocytoma Identifies αvβ8 Integrin as an Essential Regulator of Tumor-Induced Angiogenesis

por Tchaicha, Jeremy H., Mobley, Aaron K., Hossain, Mohammad G., Aldape, Kenneth D., McCarty, Joseph H.
Publicado 2010

Dendritic cell vaccines for high-grade gliomas

por Eagles, Matthew E, Nassiri, Farshad, Badhiwala, Jetan H, Suppiah, Suganth, Almenawer, Saleh A, Zadeh, Gelareh, Aldape, Kenneth D
Publicado 2018

PTEN, NHERF1 and PHLPP form a tumor suppressor network that is disabled in glioblastoma

por Molina, Jennifer R., Agarwal, Nitin K., Morales, Fabiana C., Hayashi, Yuho, Aldape, Kenneth D., Cote, Gilbert, Georgescu, Maria-Magdalena
Publicado 2011

Fibrolamellar carcinoma transcriptomic-based treatment prediction: complete response after nivolumab and ipilimumab

por Berger, Raanan, Dinstag, Gal, Tirosh, Omer, Schiff, Eyal, Kleiner, David, Aldape, Kenneth D, Ruppin, Eytan, Beker, Tuvik, Kurzrock, Razelle
Publicado 2022

The central nervous system tumor methylation classifier changes neuro-oncology practice for challenging brain tumor diagnoses and directly impacts patient care

por Karimi, Shirin, Zuccato, Jeffrey A., Mamatjan, Yasin, Mansouri, Sheila, Suppiah, Suganth, Nassiri, Farshad, Diamandis, Phedias, Munoz, David G., Aldape, Kenneth D., Zadeh, Gelareh
Publicado 2019

αvβ8 integrin interacts with RhoGDI1 to regulate Rac1 and Cdc42 activation and drive glioblastoma cell invasion

por Reyes, Steve B., Narayanan, Anjana S., Lee, Hye Shin, Tchaicha, Jeremy H., Aldape, Kenneth D., Lang, Frederick F., Tolias, Kimberly F., McCarty, Joseph H.
Publicado 2013

Nuclear GSK3β promotes tumorigenesis by phosphorylating KDM1A and inducing its deubiquitination by USP22

por Zhou, Aidong, Lin, Kangyu, Zhang, Sicong, Chen, Yaohui, Zhang, Nu, Xue, Jianfei, Wang, Zhongyong, Aldape, Kenneth D., Xie, Keping, Woodgett, James R., Huang, Suyun
Publicado 2016

Global analysis of aberrant pre-mRNA splicing in glioblastoma using exon expression arrays

por Cheung, Hannah C, Baggerly, Keith A, Tsavachidis, Spiridon, Bachinski, Linda L, Neubauer, Valerie L, Nixon, Tamara J, Aldape, Kenneth D, Cote, Gilbert J, Krahe, Ralf
Publicado 2008

Stat3 orchestrates interaction between endothelial and tumor cells and inhibition of Stat3 suppresses brain metastasis of breast cancer cells

por Lee, Hsueh-Te, Xue, Jianfei, Chou, Ping-Chieh, Zhou, Aidong, Yang, Phillip, Conrad, Charles A., Aldape, Kenneth D., Priebe, Waldemar, Patterson, Cam, Sawaya, Raymond, Xie, Keping, Huang, Suyun
Publicado 2015

Targeting hexokinase 2 enhances response to radio-chemotherapy in glioblastoma

por Vartanian, Alenoush, Agnihotri, Sameer, Wilson, Mark R., Burrell, Kelly E., Tonge, Peter D., Alamsahebpour, Amir, Jalali, Shahrzad, Taccone, Michael S., Mansouri, Sheila, Golbourn, Brian, Aldape, Kenneth D., Zadeh, Gelareh
Publicado 2016

A 64‐year‐old woman with frontal lobe lesion and drug‐resistant epilepsy

por Jin, Xueting, Abdullaev, Zied, Butman, John A., Inati, Sara K., Rahman, Shareena A., Zaghloul, Kareem A., Papanicolau‐Sengos, Antonios, Pratt, Drew W., Aldape, Kenneth D., Quezado, Martha M.
Publicado 2022

Exploratory Analysis of the Copy Number Alterations in Glioblastoma Multiforme

por Freire, Pablo, Vilela, Marco, Deus, Helena, Kim, Yong-Wan, Koul, Dimpy, Colman, Howard, Aldape, Kenneth D., Bogler, Oliver, Yung, W. K. Alfred, Coombes, Kevin, Mills, Gordon B., Vasconcelos, Ana T., Almeida, Jonas S.
Publicado 2008

Activating NTRK2 and ALK receptor tyrosine kinase fusions extend the molecular spectrum of pleomorphic xanthoastrocytomas of early childhood: a diagnostic overlap with infant-type...

por Lucas, Calixto-Hope G., Abdullaev, Zied, Bruggers, Carol S., Mirchia, Kanish, Whipple, Nicholas S., Alashari, Mouied M., Lowichik, Amy, Cheshier, Samuel, Phillips, Joanna J., Devine, Patrick, Solomon, David A., Quezado, Martha, Aldape, Kenneth D., Perry, Arie
Publicado 2021

Anti-vascular endothelial growth factor therapy-induced glioma invasion is associated with accumulation of Tie2-expressing monocytes

por Gabrusiewicz, Konrad, Liu, Dan, Cortes-Santiago, Nahir, Hossain, Mohammad B., Conrad, Charles A., Aldape, Kenneth D., Fuller, Gregory N., Marini, Frank C., Alonso, Marta M., Idoate, Miguel Angel, Gilbert, Mark R., Fueyo, Juan, Gomez-Manzano, Candelaria
Publicado 2014

A BRCA1 deficient-like signature is enriched in breast cancer brain metastases and predicts DNA damage-induced poly (ADP-ribose) polymerase inhibitor sensitivity

por McMullin, Ryan P, Wittner, Ben S, Yang, Chuanwei, Denton-Schneider, Benjamin R, Hicks, Daniel, Singavarapu, Raj, Moulis, Sharon, Lee, Jeongeun, Akbari, Mohammad R, Narod, Steven A, Aldape, Kenneth D, Steeg, Patricia S, Ramaswamy, Sridhar, Sgroi, Dennis C
Publicado 2014

A gene expression signature predicts recurrence-free survival in meningioma

por Olar, Adriana, Goodman, Lindsey D., Wani, Khalida M., Boehling, Nicholas S., Sharma, Devi S., Mody, Reema R., Gumin, Joy, Claus, Elizabeth B., Lang, Frederick F., Cloughesy, Timothy F., Lai, Albert, Aldape, Kenneth D., DeMonte, Franco, Sulman, Erik P.
Publicado 2018

Biphasic components of sarcomatoid clear cell renal cell carcinomas are molecularly similar to each other, but distinct from, non‐sarcomatoid renal carcinomas

por Sircar, Kanishka, Yoo, Suk‐Young, Majewski, Tadeusz, Wani, Khalida, Patel, Lalit R., Voicu, Horatiu, Torres‐Garcia, Wandaliz, Verhaak, Roel G. W., Tannir, Nizar, Karam, Jose A., Jonasch, Eric, Wood, Christopher G., Tamboli, Pheroze, Baggerly, Keith A., Aldape, Kenneth D., Czerniak, Bogdan
Publicado 2015

Molecular Subtypes of Glioblastoma Are Relevant to Lower Grade Glioma

por Guan, Xiaowei, Vengoechea, Jaime, Zheng, Siyuan, Sloan, Andrew E., Chen, Yanwen, Brat, Daniel J., O’Neill, Brian Patrick, de Groot, John, Yust-Katz, Shlomit, Yung, Wai-Kwan Alfred, Cohen, Mark L., Aldape, Kenneth D., Rosenfeld, Steven, Verhaak, Roeland G. W., Barnholtz-Sloan, Jill S.
Publicado 2014

Therapeutic radiation for childhood cancer drives structural aberrations of NF2 in meningiomas

por Agnihotri, Sameer, Suppiah, Suganth, Tonge, Peter D., Jalali, Shahrzad, Danesh, Arnavaz, Bruce, Jeffery P., Mamatjan, Yasin, Klironomos, George, Gonen, Lior, Au, Karolyn, Mansouri, Sheila, Karimi, Sharin, Sahm, Felix, von Deimling, Andreas, Taylor, Michael D., Laperriere, Normand J., Pugh, Trevor J., Aldape, Kenneth D., Zadeh, Gelareh
Publicado 2017