4-Arylthieno[2,3-b]pyridine-2-carboxamides Are a New Class of Antiplasmodial Agents

por Schweda, Sandra I., Alder, Arne, Gilberger, Tim, Kunick, Conrad
Publicado 2020

N-terminal phosphorylation regulates the activity of glycogen synthase kinase 3 from Plasmodium falciparum

por Pazicky, Samuel, Alder, Arne, Mertens, Haydyn, Svergun, Dmitri, Gilberger, Tim, Löw, Christian
Publicado 2022

Synthesis and Antiplasmodial Activity of Bisindolylcyclobutenediones

por Lande, Duc Hoàng, Nasereddin, Abed, Alder, Arne, Gilberger, Tim W., Dzikowski, Ron, Grünefeld, Johann, Kunick, Conrad
Publicado 2021

The role of Plasmodium V-ATPase in vacuolar physiology and antimalarial drug uptake

por Alder, Arne, Sanchez, Cecilia P., Russell, Matthew R. G., Collinson, Lucy M., Lanzer, Michael, Blackman, Michael J., Gilberger, Tim-Wolf, Matz, Joachim M.
Publicado 2023

Structure–activity relationships in a series of antiplasmodial thieno[2,3-b]pyridines

por Masch, Andreas, Nasereddin, Abed, Alder, Arne, Bird, Megan J., Schweda, Sandra I., Preu, Lutz, Doerig, Christian, Dzikowski, Ron, Gilberger, Tim W., Kunick, Conrad
Publicado 2019

Functional inactivation of Plasmodium falciparum glycogen synthase kinase GSK3 modulates erythrocyte invasion and blocks gametocyte maturation

por Alder, Arne, Wilcke, Louisa, Pietsch, Emma, von Thien, Heidrun, Pazicky, Samuel, Löw, Christian, Mesen-Ramirez, Paolo, Bachmann, Anna, Burda, Paul-Christian, Kunick, Conrad, Sondermann, Holger, Wilson, Danny, Gilberger, Tim-Wolf
Publicado 2022

PMRT1, a Plasmodium-Specific Parasite Plasma Membrane Transporter, Is Essential for Asexual and Sexual Blood Stage Development

por Wichers, Jan Stephan, Mesén-Ramírez, Paolo, Fuchs, Gwendolin, Yu-Strzelczyk, Jing, Stäcker, Jan, von Thien, Heidrun, Alder, Arne, Henshall, Isabelle, Liffner, Benjamin, Nagel, Georg, Löw, Christian, Wilson, Danny, Spielmann, Tobias, Gao, Shiqiang, Gilberger, Tim-Wolf, Bachmann, Anna, Strauss, Jan
Publicado 2022

Cell biological analysis reveals an essential role for Pfcerli2 in erythrocyte invasion by malaria parasites

por Liffner, Benjamin, Balbin, Juan Miguel, Shami, Gerald J., Siddiqui, Ghizal, Strauss, Jan, Frölich, Sonja, Heinemann, Gary K., Edwards, Ella May, Alder, Arne, Wichers, Jan Stephan, Creek, Darren J., Tilley, Leann, Dixon, Matthew W. A., Gilberger, Tim-Wolf, Wilson, Danny W.
Publicado 2022

CRISPR/Cas9-engineered inducible gametocyte producer lines as a valuable tool for Plasmodium falciparum malaria transmission research

por Boltryk, Sylwia D., Passecker, Armin, Alder, Arne, Carrington, Eilidh, van de Vegte-Bolmer, Marga, van Gemert, Geert-Jan, van der Starre, Alex, Beck, Hans-Peter, Sauerwein, Robert W., Kooij, Taco W. A., Brancucci, Nicolas M. B., Proellochs, Nicholas I., Gilberger, Tim-Wolf, Voss, Till S.
Publicado 2021