Interactions of amyloidogenic proteins with mitochondrial protein import machinery in aging-related neurodegenerative diseases

por Reed, Ashley L., Mitchell, Wayne, Alexandrescu, Andrei T., Alder, Nathan N.
Publicado 2023

The Cell-Free Integration of a Polytopic Mitochondrial Membrane Protein into Liposomes Occurs Cotranslationally and in a Lipid-Dependent Manner

por Long, Ashley R., O'Brien, Catherine C., Alder, Nathan N.
Publicado 2012

The molecular mechanisms underlying BiP-mediated gating of the Sec61 translocon of the endoplasmic reticulum

por Alder, Nathan N., Shen, Ying, Brodsky, Jeffrey L., Hendershot, Linda M., Johnson, Arthur E.
Publicado 2005

Correction

por Alder, Nathan N., Shen, Ying, Brodsky, Jeffrey L., Hendershot, Linda M., Johnson, Arthur E.
Publicado 2005

Reduction of elevated proton leak rejuvenates mitochondria in the aged cardiomyocyte

por Zhang, Huiliang, Alder, Nathan N, Wang, Wang, Szeto, Hazel, Marcinek, David J, Rabinovitch, Peter S
Publicado 2020

A detergent-free strategy for the reconstitution of active enzyme complexes from native biological membranes into nanoscale discs

por Long, Ashley R, O’Brien, Catherine C, Malhotra, Ketan, Schwall, Christine T, Albert, Arlene D, Watts, Anthony, Alder, Nathan N
Publicado 2013

Cardiolipin mediates membrane and channel interactions of the mitochondrial TIM23 protein import complex receptor Tim50

por Malhotra, Ketan, Modak, Arnab, Nangia, Shivangi, Daman, Tyler H., Gunsel, Umut, Robinson, Victoria L., Mokranjac, Dejana, May, Eric R., Alder, Nathan N.
Publicado 2017

Phosphatidylethanolamine made in the inner mitochondrial membrane is essential for yeast cytochrome bc(1) complex function

por Calzada, Elizabeth, Avery, Erica, Sam, Pingdewinde N., Modak, Arnab, Wang, Chunyan, McCaffery, J. Michael, Han, Xianlin, Alder, Nathan N., Claypool, Steven M.
Publicado 2019

Structure-activity relationships of mitochondria-targeted tetrapeptide pharmacological compounds

por Mitchell, Wayne, Tamucci, Jeffrey D, Ng, Emery L, Liu, Shaoyi, Birk, Alexander V, Szeto, Hazel H, May, Eric R, Alexandrescu, Andrei T, Alder, Nathan N
Publicado 2022

The mitochondria-targeted peptide SS-31 binds lipid bilayers and modulates surface electrostatics as a key component of its mechanism of action

por Mitchell, Wayne, Ng, Emily A., Tamucci, Jeffrey D., Boyd, Kevin J., Sathappa, Murugappan, Coscia, Adrian, Pan, Meixia, Han, Xianlin, Eddy, Nicholas A., May, Eric R., Szeto, Hazel H., Alder, Nathan N.
Publicado 2020

Conserved cardiolipin-mitochondrial ADP/ATP carrier interactions assume distinct structural and functional roles that are clinically relevant

por Senoo, Nanami, Chinthapalli, Dinesh K., Baile, Matthew G., Golla, Vinaya K., Saha, Bodhisattwa, Ogunbona, Oluwaseun B., Saba, James A., Munteanu, Teona, Valdez, Yllka, Whited, Kevin, Chorev, Dror, Alder, Nathan N., May, Eric R., Robinson, Carol V., Claypool, Steven M.
Publicado 2023