Chemokine-Adjuvanted Plasmid DNA Induces Homing of Antigen-Specific and Non–Antigen-Specific B and T Cells to the Intestinal and Genital Mucosae

por Aldon, Yoann, Kratochvil, Sven, Shattock, Robin J., McKay, Paul F.
Publicado 2020

Inside out: optimization of lipid nanoparticle formulations for exterior complexation and in vivo delivery of saRNA

por Blakney, Anna K., McKay, Paul F., Yus, Bárbara Ibarzo, Aldon, Yoann, Shattock, Robin J.
Publicado 2019

Discrete partitioning of HIV-1 Env forms revealed by viral capture

por Stieh, Daniel J., King, Deborah F., Klein, Katja, Aldon, Yoann, McKay, Paul F., Shattock, Robin J.
Publicado 2015

Intravaginal immunisation using a novel antigen-releasing ring device elicits robust vaccine antigen-specific systemic and mucosal humoral immune responses

por McKay, Paul F., Mann, Jamie F.S., Pattani, Aditya, Kett, Vicky, Aldon, Yoann, King, Deborah, Malcolm, R. Karl, Shattock, Robin J.
Publicado 2017

Identification of potential biomarkers of vaccine inflammation in mice

por McKay, Paul F, Cizmeci, Deniz, Aldon, Yoann, Maertzdorf, Jeroen, Weiner, January, Kaufmann, Stefan HE, Lewis, David JM, van den Berg, Robert A, Del Giudice, Giuseppe, Shattock, Robin J
Publicado 2019

Immunogenicity of stabilized HIV-1 Env trimers delivered by self-amplifying mRNA

por Aldon, Yoann, McKay, Paul F., Moreno Herrero, Jorge, Vogel, Annette B., Lévai, Réka, Maisonnasse, Pauline, Dereuddre-Bosquet, Nathalie, Haas, Heinrich, Fábián, Katalin, Le Grand, Roger, Sahin, Ugur, Shattock, Robin J.
Publicado 2021

Probing Affinity, Avidity, Anticooperativity, and Competition in Antibody and Receptor Binding to the SARS-CoV-2 Spike by Single Particle Mass Analyses

por Yin, Victor, Lai, Szu-Hsueh, Caniels, Tom G., Brouwer, Philip J. M., Brinkkemper, Mitch, Aldon, Yoann, Liu, Hejun, Yuan, Meng, Wilson, Ian A., Sanders, Rogier W., van Gils, Marit J., Heck, Albert J. R.
Publicado 2021

Rational Design of DNA-Expressed Stabilized Native-Like HIV-1 Envelope Trimers

por Aldon, Yoann, McKay, Paul F., Allen, Joel, Ozorowski, Gabriel, Felfödiné Lévai, Réka, Tolazzi, Monica, Rogers, Paul, He, Linling, de Val, Natalia, Fábián, Katalin, Scarlatti, Gabriella, Zhu, Jiang, Ward, Andrew B., Crispin, Max, Shattock, Robin J.
Publicado 2018

Computed tomography and [(18)F]-FDG PET imaging provide additional readouts for COVID-19 pathogenesis and therapies evaluation in non-human primates

por Naninck, Thibaut, Kahlaoui, Nidhal, Lemaitre, Julien, Maisonnasse, Pauline, De Mori, Antoine, Pascal, Quentin, Contreras, Vanessa, Marlin, Romain, Relouzat, Francis, Delache, Benoît, Hérate, Cécile, Aldon, Yoann, van Gils, Marit, Zabaleta, Nerea, Ho Tsong Fang, Raphaël, Bosquet, Nathalie, Sanders, Rogier W., Vandenberghe, Luk H., Chapon, Catherine, Le Grand, Roger
Publicado 2022

Innate cell markers that predict anti-HIV neutralizing antibody titers in vaccinated macaques

por Van Tilbeurgh, Matthieu, Maisonnasse, Pauline, Palgen, Jean-Louis, Tolazzi, Monica, Aldon, Yoann, Dereuddre-Bosquet, Nathalie, Cavarelli, Mariangela, Beignon, Anne-Sophie, Marcos-Lopez, Ernesto, Gallouet, Anne-Sophie, Gilson, Emmanuel, Ozorowski, Gabriel, Ward, Andrew B., Bontjer, Ilja, McKay, Paul F., Shattock, Robin J., Scarlatti, Gabriella, Sanders, Rogier W., Le Grand, Roger
Publicado 2022

Profound structural conservation of chemically cross-linked HIV-1 envelope glycoprotein experimental vaccine antigens

por Martin, Gregory M., Russell, Rebecca A., Mundsperger, Philip, Harris, Scarlett, Jovanoska, Lu, Trajano, Luiza Farache, Schiffner, Torben, Fabian, Katalin, Tolazzi, Monica, Scarlatti, Gabriella, McFarlane, Leon, Cheeseman, Hannah, Aldon, Yoann, Schermer, Edith E., Breemen, Marielle, Sliepen, Kwinten, Katinger, Dietmar, Kunert, Renate, Sanders, Rogier W., Shattock, Robin, Ward, Andrew B., Sattentau, Quentin J.
Publicado 2023

A Phase 1 Human Immunodeficiency Virus Vaccine Trial for Cross-Profiling the Kinetics of Serum and Mucosal Antibody Responses to CN54gp140 Modulated by Two Homologous Prime-Boost V...

por Kratochvil, Sven, McKay, Paul F., Kopycinski, Jakub T., Bishop, Cynthia, Hayes, Peter John, Muir, Luke, Pinder, Christopher L., Cizmeci, Deniz, King, Deborah, Aldon, Yoann, Wines, Bruce D., Hogarth, P. Mark, Chung, Amy W., Kent, Stephen J., Held, Kathrin, Geldmacher, Christof, Dally, Len, Santos, Nelson S., Cole, Tom, Gilmour, Jill, Fidler, Sarah, Shattock, Robin J.
Publicado 2017

Persistent immunogenicity of integrase defective lentiviral vectors delivering membrane-tethered native-like HIV-1 envelope trimers

por Gallinaro, Alessandra, Pirillo, Maria Franca, Aldon, Yoann, Cecchetti, Serena, Michelini, Zuleika, Tinari, Antonella, Borghi, Martina, Canitano, Andrea, McKay, Paul F., Bona, Roberta, Vescio, Maria Fenicia, Grasso, Felicia, Blasi, Maria, Baroncelli, Silvia, Scarlatti, Gabriella, LaBranche, Celia, Montefiori, David, Klotman, Mary E., Sanders, Rogier W., Shattock, Robin J., Negri, Donatella, Cara, Andrea
Publicado 2022

The effect of spike mutations on SARS-CoV-2 neutralization

por Rees-Spear, Chloe, Muir, Luke, Griffith, Sarah A., Heaney, Judith, Aldon, Yoann, Snitselaar, Jonne L., Thomas, Peter, Graham, Carl, Seow, Jeffrey, Lee, Nayung, Rosa, Annachiara, Roustan, Chloe, Houlihan, Catherine F., Sanders, Rogier W., Gupta, Ravindra K., Cherepanov, Peter, Stauss, Hans J., Nastouli, Eleni, Doores, Katie J., van Gils, Marit J., McCoy, Laura E.
Publicado 2021

Enhancing glycan occupancy of soluble HIV-1 envelope trimers to mimic the native viral spike

por Derking, Ronald, Allen, Joel D., Cottrell, Christopher A., Sliepen, Kwinten, Seabright, Gemma E., Lee, Wen-Hsin, Aldon, Yoann, Rantalainen, Kimmo, Antanasijevic, Aleksandar, Copps, Jeffrey, Yasmeen, Anila, Cupo, Albert, Portillo, Victor M. Cruz, Poniman, Meliawati, Bol, Niki, van der Woude, Patricia, de Taeye, Steven W., van den Kerkhof, Tom L.G.M., Klasse, P.J., Ozorowski, Gabriel, van Gils, Marit J., Moore, John P., Ward, Andrew B., Crispin, Max, Sanders, Rogier W.
Publicado 2021

A public antibody class recognizes an S2 epitope exposed on open conformations of SARS-CoV-2 spike

por Claireaux, Mathieu, Caniels, Tom G., de Gast, Marlon, Han, Julianna, Guerra, Denise, Kerster, Gius, van Schaik, Barbera D. C., Jongejan, Aldo, Schriek, Angela I., Grobben, Marloes, Brouwer, Philip J. M., van der Straten, Karlijn, Aldon, Yoann, Capella-Pujol, Joan, Snitselaar, Jonne L., Olijhoek, Wouter, Aartse, Aafke, Brinkkemper, Mitch, Bontjer, Ilja, Burger, Judith A., Poniman, Meliawati, Bijl, Tom P. L., Torres, Jonathan L., Copps, Jeffrey, Martin, Isabel Cuella, de Taeye, Steven W., de Bree, Godelieve J., Ward, Andrew B., Sliepen, Kwinten, van Kampen, Antoine H. C., Moerland, Perry D., Sanders, Rogier W., van Gils, Marit J.
Publicado 2022

Germline-targeting HIV-1 Env vaccination induces VRC01-class antibodies with rare insertions

por Caniels, Tom G., Medina-Ramírez, Max, Zhang, Jinsong, Sarkar, Anita, Kumar, Sonu, LaBranche, Alex, Derking, Ronald, Allen, Joel D., Snitselaar, Jonne L., Capella-Pujol, Joan, Sánchez, Iván del Moral, Yasmeen, Anila, Diaz, Marilyn, Aldon, Yoann, Bijl, Tom P.L., Venkatayogi, Sravani, Martin Beem, Joshua S., Newman, Amanda, Jiang, Chuancang, Lee, Wen-Hsin, Pater, Maarten, Burger, Judith A., van Breemen, Mariëlle J., de Taeye, Steven W., Rantalainen, Kimmo, LaBranche, Celia, Saunders, Kevin O., Montefiori, David, Ozorowski, Gabriel, Ward, Andrew B., Crispin, Max, Moore, John P., Klasse, Per Johan, Haynes, Barton F., Wilson, Ian A., Wiehe, Kevin, Verkoczy, Laurent, Sanders, Rogier W.
Publicado 2023

Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability

por Brouwer, Philip J. M., Caniels, Tom G., van der Straten, Karlijn, Snitselaar, Jonne L., Aldon, Yoann, Bangaru, Sandhya, Torres, Jonathan L., Okba, Nisreen M. A., Claireaux, Mathieu, Kerster, Gius, Bentlage, Arthur E. H., van Haaren, Marlies M., Guerra, Denise, Burger, Judith A., Schermer, Edith E., Verheul, Kirsten D., van der Velde, Niels, van der Kooi, Alex, van Schooten, Jelle, van Breemen, Mariëlle J., Bijl, Tom P. L., Sliepen, Kwinten, Aartse, Aafke, Derking, Ronald, Bontjer, Ilja, Kootstra, Neeltje A., Wiersinga, W. Joost, Vidarsson, Gestur, Haagmans, Bart L., Ward, Andrew B., de Bree, Godelieve J., Sanders, Rogier W., van Gils, Marit J.
Publicado 2020

Two-component spike nanoparticle vaccine protects macaques from SARS-CoV-2 infection

por Brouwer, Philip J.M., Brinkkemper, Mitch, Maisonnasse, Pauline, Dereuddre-Bosquet, Nathalie, Grobben, Marloes, Claireaux, Mathieu, de Gast, Marlon, Marlin, Romain, Chesnais, Virginie, Diry, Ségolène, Allen, Joel D., Watanabe, Yasunori, Giezen, Julia M., Kerster, Gius, Turner, Hannah L., van der Straten, Karlijn, van der Linden, Cynthia A., Aldon, Yoann, Naninck, Thibaut, Bontjer, Ilja, Burger, Judith A., Poniman, Meliawati, Mykytyn, Anna Z., Okba, Nisreen M.A., Schermer, Edith E., van Breemen, Marielle J., Ravichandran, Rashmi, Caniels, Tom G., van Schooten, Jelle, Kahlaoui, Nidhal, Contreras, Vanessa, Lemaître, Julien, Chapon, Catherine, Fang, Raphaël Ho Tsong, Villaudy, Julien, Sliepen, Kwinten, van der Velden, Yme U., Haagmans, Bart L., de Bree, Godelieve J., Ginoux, Eric, Ward, Andrew B., Crispin, Max, King, Neil P., van der Werf, Sylvie, van Gils, Marit J., Le Grand, Roger, Sanders, Rogier W.
Publicado 2021

COVA1-18 neutralizing antibody protects against SARS-CoV-2 in three preclinical models

por Maisonnasse, Pauline, Aldon, Yoann, Marc, Aurélien, Marlin, Romain, Dereuddre-Bosquet, Nathalie, Kuzmina, Natalia A., Freyn, Alec W., Snitselaar, Jonne L., Gonçalves, Antonio, Caniels, Tom G., Burger, Judith A., Poniman, Meliawati, Bontjer, Ilja, Chesnais, Virginie, Diry, Ségolène, Iershov, Anton, Ronk, Adam J., Jangra, Sonia, Rathnasinghe, Raveen, Brouwer, Philip J. M., Bijl, Tom P. L., van Schooten, Jelle, Brinkkemper, Mitch, Liu, Hejun, Yuan, Meng, Mire, Chad E., van Breemen, Mariëlle J., Contreras, Vanessa, Naninck, Thibaut, Lemaître, Julien, Kahlaoui, Nidhal, Relouzat, Francis, Chapon, Catherine, Ho Tsong Fang, Raphaël, McDanal, Charlene, Osei-Twum, Mary, St-Amant, Natalie, Gagnon, Luc, Montefiori, David C., Wilson, Ian A., Ginoux, Eric, de Bree, Godelieve J., García-Sastre, Adolfo, Schotsaert, Michael, Coughlan, Lynda, Bukreyev, Alexander, van der Werf, Sylvie, Guedj, Jérémie, Sanders, Rogier W., van Gils, Marit J., Le Grand, Roger
Publicado 2021