Development of an imidazole salt catalytic system for the preparation of bis(indolyl)methanes and bis(naphthyl)methane

por Wang, Xu, Aldrich, Courtney C.
Publicado 2019

Mitsunobu Reactions Catalytic in Phosphine and a Fully Catalytic System

por Buonomo, Joseph A, Aldrich, Courtney C
Publicado 2015

Parameterization and Application of the General Amber Force Field to Model Fluoro Substituted Furanose Moieties and Nucleosides

por Escalante, Diego E., Aldrich, Courtney C., Ferguson, David M.
Publicado 2022

Blocking ADP-ribosylation expands the anti-mycobacterial spectrum of rifamycins

por Ganapathy, Uday S., Lan, Tian, Dartois, Véronique, Aldrich, Courtney C., Dick, Thomas
Publicado 2023

8-cyanobenzothiazinone analogs with potent antitubercular activity

por Zhang, Gang, Sheng, Li, Hegde, Pooja, Li, Yan, Aldrich, Courtney C.
Publicado 2021

Mutual potentiation drives synergy between trimethoprim and sulfamethoxazole

por Minato, Yusuke, Dawadi, Surendra, Kordus, Shannon L., Sivanandam, Abiram, Aldrich, Courtney C., Baughn, Anthony D.
Publicado 2018

Psoralen Derivatives as Inhibitors of Mycobacterium tuberculosis Proteasome

por Rožman, Kaja, Alexander, Evan M., Ogorevc, Eva, Bozovičar, Krištof, Sosič, Izidor, Aldrich, Courtney C., Gobec, Stanislav
Publicado 2020

Polyketide Intermediate Mimics as Probes for Revealing Cryptic Stereochemistry of Ketoreductase Domains

por Li, Yang, Fiers, William D., Bernard, Steffen M., Smith, Janet L., Aldrich, Courtney C., Fecik, Robert A.
Publicado 2014

Tylosin polyketide synthase module 3: stereospecificity, stereoselectivity and steady-state kinetic analysis of β-processing domains via diffusible, synthetic substrates

por Fiers, William D., Dodge, Greg J., Li, Yang, Smith, Janet L., Fecik, Robert A., Aldrich, Courtney C.
Publicado 2015

ADP-ribosylation-resistant rifabutin analogs show improved bactericidal activity against drug-tolerant M. abscessus in caseum surrogate

por Xie, Min, Ganapathy, Uday S., Lan, Tian, Osiecki, Paulina, Sarathy, Jansy P., Dartois, Véronique, Aldrich, Courtney C., Dick, Thomas
Publicado 2023

Methionine Antagonizes para-Aminosalicylic Acid Activity via Affecting Folate Precursor Biosynthesis in Mycobacterium tuberculosis

por Howe, Michael D., Kordus, Shannon L., Cole, Malcolm S., Bauman, Allison A., Aldrich, Courtney C., Baughn, Anthony D., Minato, Yusuke
Publicado 2018

Targeting intracellular p-aminobenzoic acid production potentiates the anti-tubercular action of antifolates

por Thiede, Joshua M., Kordus, Shannon L., Turman, Breanna J., Buonomo, Joseph A., Aldrich, Courtney C., Minato, Yusuke, Baughn, Anthony D.
Publicado 2016

Whole-Cell Screen of Fragment Library Identifies Gut Microbiota Metabolite Indole Propionic Acid as Antitubercular

por Negatu, Dereje A., Liu, Joe J. J., Zimmerman, Matthew, Kaya, Firat, Dartois, Véronique, Aldrich, Courtney C., Gengenbacher, Martin, Dick, Thomas
Publicado 2018

A Large-Scale High-Throughput Screen for Modulators of SERCA Activity

por Bidwell, Philip A., Yuen, Samantha L., Li, Ji, Berg, Kaja, Rebbeck, Robyn T., Aldrich, Courtney C., Roopnarine, Osha, Cornea, Razvan L., Thomas, David D.
Publicado 2022

Structures of Two Distinct Conformations of holo-Nonribosomal Peptide Synthetases

por Drake, Eric J., Miller, Bradley R., Shi, Ce, Tarrasch, Jeffrey T., Sundlov, Jesse A., Allen, C. Leigh, Skiniotis, Georgios, Aldrich, Courtney C., Gulick, Andrew M.
Publicado 2016

FRET assay for live-cell high-throughput screening of the cardiac SERCA pump yields multiple classes of small-molecule allosteric modulators

por Roopnarine, Osha, Yuen, Samantha L., Thompson, Andrew R., Roelike, Lauren N., Rebbeck, Robyn T., Bidwell, Phillip A., Aldrich, Courtney C., Cornea, Razvan L., Thomas, David D.
Publicado 2023

Fluorescence lifetime FRET assay for live-cell high-throughput screening of the cardiac SERCA pump yields multiple classes of small-molecule allosteric modulators

por Roopnarine, Osha, Yuen, Samantha L., Thompson, Andrew R., Roelike, Lauren N., Rebbeck, Robyn T., Bidwell, Philip A., Aldrich, Courtney C., Cornea, Razvan L., Thomas, David D.
Publicado 2023

Blocking Bacterial Naphthohydroquinone Oxidation and ADP-Ribosylation Improves Activity of Rifamycins against Mycobacterium abscessus

por Ganapathy, Uday S., Lan, Tian, Krastel, Philipp, Lindman, Marissa, Zimmerman, Matthew D., Ho, HsinPin, Sarathy, Jansy P., Evans, Joanna C., Dartois, Véronique, Aldrich, Courtney C., Dick, Thomas
Publicado 2021

Evaluating the Sensitivity of Mycobacterium tuberculosis to Biotin Deprivation Using Regulated Gene Expression

por Woong Park, Sae, Klotzsche, Marcus, Wilson, Daniel J., Boshoff, Helena I., Eoh, Hyungjin, Manjunatha, Ujjini, Blumenthal, Antje, Rhee, Kyu, Barry, Clifton E., Aldrich, Courtney C., Ehrt, Sabine, Schnappinger, Dirk
Publicado 2011

Redesign of Rifamycin Antibiotics to Overcome ADP‐Ribosylation‐Mediated Resistance

por Lan, Tian, Ganapathy, Uday S., Sharma, Sachin, Ahn, Yong‐Mo, Zimmerman, Matthew, Molodtsov, Vadim, Hegde, Pooja, Gengenbacher, Martin, Ebright, Richard H., Dartois, Véronique, Freundlich, Joel S., Dick, Thomas, Aldrich, Courtney C.
Publicado 2022