Tools to develop antibiotic combinations that target drug tolerance in Mycobacterium tuberculosis

por Greenstein, Talia, Aldridge, Bree B.
Publicado 2023

Stable Regulation of Cell Cycle Events in Mycobacteria: Insights From Inherently Heterogeneous Bacterial Populations

por Logsdon, Michelle M., Aldridge, Bree B.
Publicado 2018

Prediction of ultra-high-order antibiotic combinations based on pairwise interactions

por Katzir, Itay, Cokol, Murat, Aldridge, Bree B., Alon, Uri
Publicado 2019

Exploitation of Mycobacterium tuberculosis Reporter Strains to Probe the Impact of Vaccination at Sites of Infection

por Sukumar, Neelima, Tan, Shumin, Aldridge, Bree B., Russell, David G.
Publicado 2014

Lyapunov exponents and phase diagrams reveal multi-factorial control over TRAIL-induced apoptosis

por Aldridge, Bree B, Gaudet, Suzanne, Lauffenburger, Douglas A, Sorger, Peter K
Publicado 2011

Efficient measurement and factorization of high-order drug interactions in Mycobacterium tuberculosis

por Cokol, Murat, Kuru, Nurdan, Bicak, Ece, Larkins-Ford, Jonah, Aldridge, Bree B.
Publicado 2017

Design principles to assemble drug combinations for effective tuberculosis therapy using interpretable pairwise drug response measurements

por Larkins-Ford, Jonah, Degefu, Yonatan N., Van, Nhi, Sokolov, Artem, Aldridge, Bree B.
Publicado 2022

Fuzzy Logic Analysis of Kinase Pathway Crosstalk in TNF/EGF/Insulin-Induced Signaling

por Aldridge, Bree B., Saez-Rodriguez, Julio, Muhlich, Jeremy L., Sorger, Peter K., Lauffenburger, Douglas A.
Publicado 2009

Transcriptomic Signatures Predict Regulators of Drug Synergy and Clinical Regimen Efficacy against Tuberculosis

por Ma, Shuyi, Jaipalli, Suraj, Larkins-Ford, Jonah, Lohmiller, Jenny, Aldridge, Bree B., Sherman, David R., Chandrasekaran, Sriram
Publicado 2019

Stress-Induced Reorganization of the Mycobacterial Membrane Domain

por Hayashi, Jennifer M., Richardson, Kirill, Melzer, Emily S., Sandler, Steven J., Aldridge, Bree B., Siegrist, M. Sloan, Morita, Yasu S.
Publicado 2018

Systematic measurement of combination-drug landscapes to predict in vivo treatment outcomes for tuberculosis

por Larkins-Ford, Jonah, Greenstein, Talia, Van, Nhi, Degefu, Yonatan N., Olson, Michaela C., Sokolov, Artem, Aldridge, Bree B.
Publicado 2021

Semi-automated colony-forming unit counting for biosafety level 3 laboratories

por Janakiraman, Soorya, Engels, Sophie, Nanda, Pariksheet, Budak, Maral, Greenstein, Talia, Moraes, Mariana Pereira, Aldridge, Bree B., Kirschner, Denise E.
Publicado 2023

Protein Complexes and Proteolytic Activation of the Cell Wall Hydrolase RipA Regulate Septal Resolution in Mycobacteria

por Chao, Michael C., Kieser, Karen J., Minami, Shoko, Mavrici, Daniela, Aldridge, Bree B., Fortune, Sarah M., Alber, Tom, Rubin, Eric J.
Publicado 2013

Rv0004 is a new essential member of the mycobacterial DNA replication machinery

por Mann, Katherine M., Huang, Deborah L., Hooppaw, Anna J., Logsdon, Michelle M., Richardson, Kirill, Lee, Hark Joon, Kimmey, Jacqueline M., Aldridge, Bree B., Stallings, Christina L.
Publicado 2017

Multiscale Model Identifies Improved Schedule for Treatment of Acute Myeloid Leukemia In Vitro With the Mcl‐1 Inhibitor AZD5991

por Goliaei, Ardeshir, Woods, Haley A., Tron, Adriana E., Belmonte, Matthew A., Secrist, J. Paul, Ferguson, Douglas, Drew, Lisa, Fretland, Adrian J., Aldridge, Bree B., Gibbons, Francis D.
Publicado 2020

Localization of EccA(3) at the growing pole in Mycobacterium smegmatis

por Kriel, Nastassja L., Newton-Foot, Mae, Bennion, Owen T., Aldridge, Bree B., Mehaffy, Carolina, Belisle, John T., Walzl, Gerhard, Warren, Robin M., Sampson, Samantha L., Gey van Pittius, Nico C.
Publicado 2022

Novel Synergies and Isolate Specificities in the Drug Interaction Landscape of Mycobacterium abscessus

por Van, Nhi, Degefu, Yonatan N., Leus, Pathricia A., Larkins-Ford, Jonah, Klickstein, Jacob, Maurer, Florian P., Stone, David, Poonawala, Husain, Thorpe, Cheleste M., Smith, Trever C., Aldridge, Bree B.
Publicado 2023

Morphological profiling of tubercle bacilli identifies drug pathways of action

por Smith, Trever C., Pullen, Krista M., Olson, Michaela C., McNellis, Morgan E., Richardson, Ian, Hu, Sophia, Larkins-Ford, Jonah, Wang, Xin, Freundlich, Joel S., Ando, D. Michael, Aldridge, Bree B.
Publicado 2020

Identification of cell wall synthesis inhibitors active against Mycobacterium tuberculosis by competitive activity-based protein profiling

por Li, Michael, Patel, Hiren V., Cognetta, Armand B., Smith, Trever C., Mallick, Ivy, Cavalier, Jean-François, Previti, Mary L., Canaan, Stéphane, Aldridge, Bree B., Cravatt, Benjamin F., Seeliger, Jessica C.
Publicado 2022

Pharmacokinetics and Target Attainment of SQ109 in Plasma and Human-Like Tuberculosis Lesions in Rabbits

por Egbelowo, Oluwaseun, Sarathy, Jansy P., Gausi, Kamunkhwala, Zimmerman, Matthew D., Wang, Han, Wijnant, Gert-Jan, Kaya, Firat, Gengenbacher, Martin, Van, Nhi, Degefu, Yonatan, Nacy, Carol, Aldridge, Bree B., Carter, Claire L., Denti, Paolo, Dartois, Véronique
Publicado 2021